C4B63_35g116

VPS13A C
Trypanosoma cruzi Dm28c 2018 OG6: OG6_139067 OG7: OG7_0001856 48 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 48 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_186g7 ⚠
cleavage and polyadenylation specificity fact
— OG6
C4B63_4g103 ⚠
intraflagellar transport protein 140
— OG6
C4B63_6g418 ⚠
protein kinase
— OG6
C4B63_278g6 ⚠
endosomal trafficking protein RME-8
— OG6
C4B63_18g71 ⚠
cyclosome subunit
— OG6
C4B63_28g123 ⚠
conserved hypothetical protein
— OG6
C4B63_10g105 ⚠
kinesin protein
— OG6
C4B63_48g156 ⚠
conserved hypothetical protein
— OG6
C4B63_48g155 ⚠
conserved hypothetical protein
— OG6
C4B63_4g480 ⚠
Flagellum attachment zone protein 7(fragment)
— OG6
C4B63_127g30 ⚠
Flagellum attachment zone protein 14
— OG6
C4B63_86g55 ⚠
Probable E3 ubiquitin-protein ligase HERC3
— OG6
C4B63_9g223 ⚠
Cilia- and flagella-associated protein 57
— OG6
C4B63_18g325 ⚠
endosomal trafficking protein RME-8
— OG6
C4B63_18g72 ⚠
cyclosome subunit
— OG6
C4B63_143g33 ⚠
inorganic polyphosphate/ATP-NAD kinase
— OG6
C4B63_30g176 ⚠
inorganic polyphosphate/ATP-NAD kinase
— OG6
C4B63_85g63 ⚠
Rab-GTPase-TBC domain containing protein
— OG6
C4B63_38g151 ⚠
tetratricopeptide repeat protein (TPR)
— OG6
C4B63_38g152 ⚠
tetratricopeptide repeat protein (TPR)
— OG6
C4B63_128g60 ⚠
zinc-finger protein family member
— OG6
C4B63_34g309 ⚠
proteasome regulatory non-ATPase subunit 6
— OG6
C4B63_41g200 ⚠
Anaphase-promoting complex subunit 8
— OG6
C4B63_1g57 ⚠
AAA ATPase
— OG6
C4B63_61g130 ⚠
Regulator of chromosome condensation (RCC1) r
— OG6
C4B63_14g250 ⚠
Anaphase-promoting complex subunit 3
— OG6
C4B63_89g51 ⚠
FYVE zinc-finger containing protein
— OG6
C4B63_56g95 ⚠
paraflagellar rod protein
— OG6
C4B63_10g106 ⚠
kinesin
— OG6
C4B63_2g291 ⚠
regulator of chromosome condensation (RCC1)
— OG6
C4B63_8g495 ⚠
Regulator of chromosome condensation (RCC1) r
— OG6
C4B63_19g83 ⚠
Regulatory-associated protein of TOR1
— OG6
C4B63_4g481 ⚠
Flagellum attachment zone protein 7
— OG6
C4B63_42g254 ⚠
conserved hypothetical protein
— OG6
C4B63_48g154 ⚠
conserved hypothetical protein
— OG6
C4B63_23g82 ⚠
conserved hypothetical protein
— OG6
C4B63_26g246 ⚠
protein kinase
— OG6
C4B63_17g128 ⚠
cleavage and polyadenylation specificity fact
— OG6
C4B63_48g157 ⚠
Putative vacuolar protein sorting-associated
— OG6
C4B63_32g247 ⚠
conserved hypothetical protein
— OG6
C4B63_48g153 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG6
C4B63_28g122 ⚠
conserved hypothetical protein
— OG6
C4B63_80g10 ⚠
E3 ubiquitin-protein ligase HECTD3
— OG6
C4B63_19g137 ⚠
cleavage and polyadenylation specificity fact
— OG6
C4B63_4g244 ⚠
ankyrin repeat family protein
— OG6
C4B63_80g9 ⚠
conserved hypothetical protein
— OG6
C4B63_8g493 ⚠
regulator of chromosome condensation
— OG6
C4B63_9g224 ⚠
Cilia- and flagella-associated protein 57
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.