C4B63_14g250

Anaphase-promoting complex subunit 3
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101939 OG7: OG7_0003813 120 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 120 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_4g525 ⚠
anaphase promoting complex, subunit 10-like p
— +2 more Both
C4B63_41g200 ⚠
Anaphase-promoting complex subunit 8
— Both
C4B63_30g273 ⚠
conserved hypothetical protein
— Both
C4B63_163g31 ⚠
conserved hypothetical protein
— Both
C4B63_42g168 ⚠
CDC16
— +2 more Both
C4B63_28g122 ⚠
conserved hypothetical protein
— +2 more Both
C4B63_18g72 ⚠
cyclosome subunit
— +2 more Both
C4B63_28g123 ⚠
conserved hypothetical protein
— +2 more Both
C4B63_18g71 ⚠
cyclosome subunit
— +2 more Both
C4B63_2g828 ⚠
ankyrin repeat protein
— OG7
C4B63_87g21 ⚠
conserved hypothetical protein
— OG7
C4B63_7g57 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_87g20 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_7g67 ⚠
Sec7 guanine-nucleotide exchange factor
— OG7
C4B63_7g68 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_22g288 ⚠
Midasin
— OG7
C4B63_42g199 ⚠
conserved hypothetical protein
— OG7
C4B63_31g98 ⚠
Autophagy protein Apg6
— OG7
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_7g424 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_56g58 ⚠
ankyrin,
— OG7
C4B63_10g125 ⚠
ankyrin
— OG7
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_42g198 ⚠
conserved hypothetical protein
— OG7
C4B63_43g187 ⚠
structural maintenance of chromosome protein
— OG7
C4B63_220g9 ⚠
conserved hypothetical protein
— OG7
C4B63_63g101 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
C4B63_127g31 ⚠
Flagellum attachment zone protein 14
— OG7
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— OG7
C4B63_14g249 ⚠
structural maintenance of chromosome 3
— OG7
C4B63_32g248 ⚠
conserved hypothetical protein
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_4g111 ⚠
conserved hypothetical protein
— OG7
C4B63_205g20 ⚠
conserved hypothetical protein
— OG7
C4B63_7g306 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_13g243 ⚠
intraflagellar transport protein 122B(fragmen
— OG7
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_42g174 ⚠
conserved hypothetical protein
— OG7
C4B63_10g132 ⚠
conserved hypothetical protein
— OG7
C4B63_205g22 ⚠
Abnormal spindle-like microcephaly-associated
— OG7
C4B63_20g154 ⚠
Flagellar Member 7
— OG7
C4B63_31g1443c ⚠
RING-box protein 1
— OG7
C4B63_58g35 ⚠
E3 ubiquitin-protein ligase RBX1
— OG7
C4B63_31g221 ⚠
RING-box protein 1A
— OG7
C4B63_46g32 ⚠
E3 ubiquitin-protein ligase HERC2
— OG7
C4B63_43g216 ⚠
Tetratricopeptide repeat
— OG7
C4B63_205g21 ⚠
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.