C4B63_14g249

structural maintenance of chromosome 3
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101492 OG7: OG7_0001761 272 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 272 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_220g9 ⚠
conserved hypothetical protein
— OG7
C4B63_263g3 ⚠
conserved hypothetical protein
— OG7
C4B63_2g60 ⚠
conserved hypothetical protein
— OG7
C4B63_175g16 ⚠
Pre-mRNA-processing factor 19
— OG7
C4B63_42g232 ⚠
ubiquitin hydrolase
— OG7
C4B63_204g23 ⚠
Axonemal inner arm dynein light chain
— OG7
C4B63_18g295 ⚠
conserved hypothetical protein
— OG7
C4B63_17g128 ⚠
cleavage and polyadenylation specificity fact
— OG7
C4B63_255g16 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_31g109 ⚠
ribose-phosphate pyrophosphokinase
— OG7
C4B63_81g51 ⚠
conserved hypothetical protein
— OG7
C4B63_4g111 ⚠
conserved hypothetical protein
— OG7
C4B63_43g196 ⚠
adenylate kinase 1
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
C4B63_2g61 ⚠
conserved hypothetical protein
— OG7
C4B63_32g248 ⚠
conserved hypothetical protein
— OG7
C4B63_199g20 ⚠
conserved hypothetical protein
— OG7
C4B63_42g107 ⚠
conserved hypothetical protein
— OG7
C4B63_51g192 ⚠
protein kinase A regulatory subunit
— OG7
C4B63_127g31 ⚠
Flagellum attachment zone protein 14
— OG7
C4B63_4g478 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
C4B63_358g16 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_40g106 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
C4B63_63g32 ⚠
adaptin-related protein-like
— OG7
C4B63_9g328 ⚠
conserved hypothetical protein
— OG7
C4B63_14g147 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
C4B63_14g87 ⚠
conserved hypothetical protein
— OG7
C4B63_19g266 ⚠
conserved hypothetical protein
— OG7
C4B63_30g181 ⚠
rRNA methyltransferase 1, mitochondrial
— OG7
C4B63_104g75 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_104g76 ⚠
RNA polymerase IIA largest subunit
— OG7
C4B63_14g103 ⚠
beta adaptin
— OG7
C4B63_17g49 ⚠
Pab1p-dependent poly(A) ribonuclease subunit
— OG7
C4B63_168g31 ⚠
dynein arm light chain
— OG7
C4B63_4g201 ⚠
Protein ILITYHIA
— OG7
C4B63_48g123 ⚠
neurobeachin/beige protein
— OG7
C4B63_48g124 ⚠
neurobeachin/beige protein
— OG7
C4B63_55g67 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
C4B63_7g87 ⚠
Alpha,alpha-trehalose phosphorylase
— OG7
C4B63_80g25 ⚠
ubiquitin hydrolase
— OG7
C4B63_9g329 ⚠
Beige/BEACH domain
— OG7
C4B63_59g118 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
C4B63_19g123 ⚠
RNA-binding protein
— OG7
C4B63_173g3 ⚠
histone deacetylase
— OG7
C4B63_4g202 ⚠
Periodic tryptophan protein 2 homolog
— OG7
C4B63_31g166 ⚠
histone deacetylase 4
— OG7
C4B63_173g4 ⚠
histone deacetylase
— OG7
C4B63_28g113 ⚠
dynein arm light chain
— OG7
C4B63_60g174 ⚠
adenylate kinase
— OG7
C4B63_44g250 ⚠
DNA-directed RNA polymerase II subunit 2
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.