C4B63_10g106

kinesin
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146781 OG7: OG7_0000136 97 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 97 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_17g128 ⚠
cleavage and polyadenylation specificity fact
— OG6
C4B63_17g276 ⚠
TRAF3-interacting protein 1
— OG6
C4B63_63g98 ⚠
ubiquitin-protein ligase
— OG6
C4B63_18g71 ⚠
cyclosome subunit
— OG6
C4B63_278g6 ⚠
endosomal trafficking protein RME-8
— OG6
C4B63_17g45 ⚠
kinesin
— OG6
C4B63_4g103 ⚠
intraflagellar transport protein 140
— OG6
C4B63_80g9 ⚠
conserved hypothetical protein
— OG6
C4B63_80g10 ⚠
E3 ubiquitin-protein ligase HECTD3
— OG6
C4B63_7g424 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG6
C4B63_48g153 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG6
C4B63_4g531 ⚠
Cleavage stimulation factor subunit 1
— OG6
C4B63_48g157 ⚠
Putative vacuolar protein sorting-associated
— OG6
C4B63_48g156 ⚠
conserved hypothetical protein
— OG6
C4B63_23g82 ⚠
conserved hypothetical protein
— OG6
C4B63_48g154 ⚠
conserved hypothetical protein
— OG6
C4B63_42g254 ⚠
conserved hypothetical protein
— OG6
C4B63_63g101 ⚠
Phosphatidylinositol 3-kinase tor1
— OG6
C4B63_11g50 ⚠
General negative regulator of transcription s
— OG6
C4B63_4g480 ⚠
Flagellum attachment zone protein 7(fragment)
— OG6
C4B63_4g481 ⚠
Flagellum attachment zone protein 7
— OG6
C4B63_79g36 ⚠
CCR4-NOT transcription complex subunit 1
— OG6
C4B63_86g69 ⚠
mucin TcMUCII
— OG6
C4B63_6g418 ⚠
protein kinase
— OG6
C4B63_128g60 ⚠
zinc-finger protein family member
— OG6
C4B63_24g196 ⚠
microtubule-associated protein
— OG6
C4B63_76g43 ⚠
proteasome regulatory ATPase subunit 1
— OG6
C4B63_1g57 ⚠
AAA ATPase
— OG6
C4B63_28g123 ⚠
conserved hypothetical protein
— OG6
C4B63_28g122 ⚠
conserved hypothetical protein
— OG6
C4B63_49g160 ⚠
ATP-dependent DEAD/H RNA helicase
— OG6
C4B63_293g23 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g24 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g21 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g22 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_89g42 ⚠
translation initiation factor EIF-2b alpha su
— OG6
C4B63_41g200 ⚠
Anaphase-promoting complex subunit 8
— OG6
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— OG6
C4B63_24g194 ⚠
microtubule-associated protein
— OG6
C4B63_24g195 ⚠
microtubule-associated protein
— OG6
C4B63_52g40 ⚠
immunodominant antigen
— OG6
C4B63_19g83 ⚠
Regulatory-associated protein of TOR1
— OG6
C4B63_4g244 ⚠
ankyrin repeat family protein
— OG6
C4B63_18g72 ⚠
cyclosome subunit
— OG6
C4B63_18g325 ⚠
endosomal trafficking protein RME-8
— OG6
C4B63_186g7 ⚠
cleavage and polyadenylation specificity fact
— OG6
C4B63_13g334 ⚠
conserved hypothetical protein
— OG6
C4B63_127g30 ⚠
Flagellum attachment zone protein 14
— OG6
C4B63_48g155 ⚠
conserved hypothetical protein
— OG6
C4B63_9g224 ⚠
Cilia- and flagella-associated protein 57
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.