C4B63_13g334

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_139733 OG7: OG7_0034031 138 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 138 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— Both
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— Both
C4B63_63g101 ⚠
Phosphatidylinositol 3-kinase tor1
— Both
C4B63_7g424 ⚠
phosphatidylinositol 3-kinase(fragment)
— Both
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_22g113 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_24g196 ⚠
microtubule-associated protein
— Both
C4B63_61g125
ssm4 protein
— Both
C4B63_89g42 ⚠
translation initiation factor EIF-2b alpha su
— Both
C4B63_293g22 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g21 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g24 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g23 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_49g160 ⚠
ATP-dependent DEAD/H RNA helicase
— OG6
C4B63_1g57
AAA ATPase
— Both
C4B63_76g43
proteasome regulatory ATPase subunit 1
— OG6
C4B63_55g168 ⚠
Cilia- and flagella-associated protein 57
— OG7
C4B63_281g8 ⚠
translation initiation factor eIF2B delta sub
— OG7
C4B63_21g61 ⚠
guanine nucleotide exchange factor subunit GC
— OG7
C4B63_19g15 ⚠
translation initiation factor eIF2B delta sub
— OG7
C4B63_81g15 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_7g56 ⚠
Protein transport protein sec71
— OG7
C4B63_81g14 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_7g55 ⚠
conserved hypothetical protein
— OG7
C4B63_7g57 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_7g67 ⚠
Sec7 guanine-nucleotide exchange factor
— OG7
C4B63_7g68 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_6g252 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_41g73 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_248g25 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_43g154 ⚠
TRAF3-interacting protein 1
— OG7
C4B63_42g199 ⚠
conserved hypothetical protein
— OG7
C4B63_42g198 ⚠
conserved hypothetical protein
— OG7
C4B63_12g218
Zinc finger HIT domain-containing protein 1
— OG7
C4B63_271g11 ⚠
conserved hypothetical protein
— OG7
C4B63_43g203 ⚠
conserved hypothetical protein
— OG7
C4B63_13g257 ⚠
endonuclease/exonuclease/phosphatase
— OG7
C4B63_52g48 ⚠
conserved hypothetical protein
— OG7
C4B63_25g220 ⚠
5'-3' exoribonuclease B
— OG7
C4B63_31g46 ⚠
structural maintenance of chromosome 3 protei
— OG7
C4B63_2g729 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
C4B63_2g203 ⚠
synaptojanin (N-terminal domain)
— OG7
C4B63_153g40 ⚠
inositol 5-phosphatase 1
— OG7
C4B63_72g79 ⚠
inositol 5-phosphatase 1
— OG7
C4B63_396g8 ⚠
synaptojanin (N-terminal domain)
— OG7
C4B63_80g15 ⚠
cAMP response protein 1
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.