C4B63_12g218

Zinc finger HIT domain-containing protein 1
Trypanosoma cruzi Dm28c 2018 OG6: OG6_104246 OG7: OG7_0009320 47 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 47 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_42g85
conserved hypothetical protein
— OG7
C4B63_168g31 ⚠
dynein arm light chain
— OG7
C4B63_9g328 ⚠
conserved hypothetical protein
— OG7
C4B63_204g23 ⚠
Axonemal inner arm dynein light chain
— OG7
C4B63_2g203 ⚠
synaptojanin (N-terminal domain)
— OG7
C4B63_153g40 ⚠
inositol 5-phosphatase 1
— OG7
C4B63_112g14 ⚠
neurobeachin/beige-like protein
— OG7
C4B63_102g78 ⚠
dynein arm light chain
— OG7
C4B63_2g826
conserved hypothetical protein
— OG7
C4B63_41g73 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_25g218 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_13g297 ⚠
Axonemal inner arm dynein light chain
— OG7
C4B63_52g48 ⚠
conserved hypothetical protein
— OG7
C4B63_20g38 ⚠
Synaptojanin
— OG7
C4B63_48g122 ⚠
neurobeachin/beige protein
— OG7
C4B63_28g111 ⚠
synaptojanin
— OG7
C4B63_248g25 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_8g48 ⚠
dynein arm light chain
— OG7
C4B63_112g13 ⚠
neurobeachin/beige-like protein(fragment)
— OG7
C4B63_13g334
conserved hypothetical protein
— OG7
C4B63_153g41 ⚠
inositol 5-phosphatase 1(fragment)
— OG7
C4B63_25g219 ⚠
conserved hypothetical protein
— OG7
C4B63_10g409
Present in the outer mitochondrial membrane p
— OG7
C4B63_396g8 ⚠
synaptojanin (N-terminal domain)
— OG7
C4B63_48g124 ⚠
neurobeachin/beige protein
— OG7
C4B63_7g56 ⚠
Protein transport protein sec71
— OG7
C4B63_81g14 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_7g55 ⚠
conserved hypothetical protein
— OG7
C4B63_87g21 ⚠
conserved hypothetical protein
— OG7
C4B63_7g57 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_87g20 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_7g67 ⚠
Sec7 guanine-nucleotide exchange factor
— OG7
C4B63_7g68 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_271g11 ⚠
conserved hypothetical protein
— OG7
C4B63_28g113 ⚠
dynein arm light chain
— OG7
C4B63_9g329 ⚠
Beige/BEACH domain
— OG7
C4B63_81g15 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_48g123 ⚠
neurobeachin/beige protein
— OG7
C4B63_2g359
DDB1- and CUL4-associated factor 1
— OG7
C4B63_72g79 ⚠
inositol 5-phosphatase 1
— OG7
C4B63_6g252 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_52g47 ⚠
conserved hypothetical protein
— OG7
C4B63_9g327 ⚠
conserved hypothetical protein
— OG7
C4B63_13g257 ⚠
endonuclease/exonuclease/phosphatase
— OG7
C4B63_43g203 ⚠
conserved hypothetical protein
— OG7
C4B63_2g13
Centrosomal protein of 131 kDa
— OG7
C4B63_26g245 ⚠
inositol/phosphatidylinositol phosphatase
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.