C4B63_2g203

synaptojanin (N-terminal domain)
Trypanosoma cruzi Dm28c 2018 OG6: OG6_137054 OG7: OG7_0000974 129 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 129 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_24g190 ⚠
Exportin-7
— OG7
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— OG7
C4B63_12g218 ⚠
Zinc finger HIT domain-containing protein 1
— OG7
C4B63_17g69 ⚠
phenylalanyl-tRNA synthetase alpha chain
— OG7
C4B63_297g14 ⚠
phenylalanyl-tRNA synthetase alpha chain
— OG7
C4B63_271g11 ⚠
conserved hypothetical protein
— OG7
C4B63_122g21 ⚠
ubiquitin ligase
— OG7
C4B63_4g116 ⚠
FACT complex subunit ssrp1-B
— OG7
C4B63_43g203 ⚠
conserved hypothetical protein
— OG7
C4B63_27g4 ⚠
ubiquitin ligase
— OG7
C4B63_16g105 ⚠
coronin
— OG7
C4B63_101g15 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
C4B63_70g126 ⚠
conserved hypothetical protein
— OG7
C4B63_7g417 ⚠
snoRNP protein GAR1
— OG7
C4B63_80g25 ⚠
ubiquitin hydrolase
— OG7
C4B63_32g255 ⚠
WD domain, G-beta repeat
— OG7
C4B63_2g83 ⚠
ubiquitin hydrolase
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_32g256 ⚠
PFU (PLAA family ubiquitin binding)
— OG7
C4B63_2g502 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_252g9 ⚠
ubiquitin carboxyl-terminal hydrolase
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_2g513 ⚠
conserved hypothetical protein
— OG7
C4B63_2g566 ⚠
phenylalanyl-tRNA synthetase
— OG7
C4B63_204g23 ⚠
Axonemal inner arm dynein light chain
— OG7
C4B63_102g78 ⚠
dynein arm light chain
— OG7
C4B63_28g113 ⚠
dynein arm light chain
— OG7
C4B63_168g31 ⚠
dynein arm light chain
— OG7
C4B63_13g297 ⚠
Axonemal inner arm dynein light chain
— OG7
C4B63_8g48 ⚠
dynein arm light chain
— OG7
C4B63_7g395 ⚠
conserved hypothetical protein
— OG7
C4B63_83g73 ⚠
ribonucleoprotein p18, mitochondrial precurso
— OG7
C4B63_10g409 ⚠
Present in the outer mitochondrial membrane p
— OG7
C4B63_13g334 ⚠
conserved hypothetical protein
— OG7
C4B63_112g13 ⚠
neurobeachin/beige-like protein(fragment)
— OG7
C4B63_48g122 ⚠
neurobeachin/beige protein
— OG7
C4B63_42g85 ⚠
conserved hypothetical protein
— OG7
C4B63_2g826 ⚠
conserved hypothetical protein
— OG7
C4B63_112g14 ⚠
neurobeachin/beige-like protein
— OG7
C4B63_9g328 ⚠
conserved hypothetical protein
— OG7
C4B63_2g13 ⚠
Centrosomal protein of 131 kDa
— OG7
C4B63_9g327 ⚠
conserved hypothetical protein
— OG7
C4B63_2g359 ⚠
DDB1- and CUL4-associated factor 1
— OG7
C4B63_48g123 ⚠
neurobeachin/beige protein
— OG7
C4B63_48g124 ⚠
neurobeachin/beige protein
— OG7
C4B63_9g329 ⚠
Beige/BEACH domain
— OG7
C4B63_32g238 ⚠
tubulin folding cofactor D
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.