C4B63_76g43

proteasome regulatory ATPase subunit 1
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101899 OG7: OG7_0000949 97 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 97 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_46g106
proteasome regulatory ATPase subunit 2
— OG6
C4B63_80g34
proteasome regulatory non-ATPase subunit 7
— OG6
C4B63_79g26 ⚠
proteasome regulatory non-ATP-ase subunit 5
— OG6
C4B63_23g31
26S protease regulatory subunit
— OG6
C4B63_76g37
proteasome regulatory ATPase subunit 5
— OG6
C4B63_14g170
19S proteasome regulatory subunit
— OG6
C4B63_79g28 ⚠
proteasome regulatory non-ATP-ase subunit 5
— OG6
C4B63_47g88
proteasome regulatory non-ATPase subunit 11
— OG6
C4B63_78g44
proteasome regulatory non-ATPase subunit
— OG6
C4B63_202g4 ⚠
proteasome regulatory ATPase subunit 3
— OG6
C4B63_89g62 ⚠
proteasome regulatory ATPase subunit 3
— OG6
C4B63_17g111
proteasome regulatory non-ATP-ase subunit
— OG6
C4B63_4g528
proteasome regulatory non-ATP-ase subunit 9
— OG6
C4B63_34g309
proteasome regulatory non-ATPase subunit 6
— OG6
C4B63_2g527
proteasome regulatory non-ATPase subunit 3
— OG6
C4B63_4g531
Cleavage stimulation factor subunit 1
— OG6
C4B63_4g92
19S proteasome non-atpase subunit 8
— OG6
C4B63_10g510 ⚠
26S proteasome regulatory non-ATPase subunit
— OG6
C4B63_10g511 ⚠
26S proteasome regulatory non-ATPase subunit
— OG6
C4B63_6g421
proteasome regulatory non-ATPase subunit 2
— OG6
C4B63_4g481 ⚠
Flagellum attachment zone protein 7
— OG6
C4B63_79g36 ⚠
CCR4-NOT transcription complex subunit 1
— OG6
C4B63_86g69 ⚠
mucin TcMUCII
— OG6
C4B63_4g480 ⚠
Flagellum attachment zone protein 7(fragment)
— OG6
C4B63_6g523
conserved hypothetical protein
— OG6
C4B63_52g40
immunodominant antigen
— OG6
C4B63_89g42
translation initiation factor EIF-2b alpha su
— OG6
C4B63_1g57
AAA ATPase
— OG6
C4B63_34g361
phosphatidylinositol kinase related protein
— OG6
C4B63_38g152 ⚠
tetratricopeptide repeat protein (TPR)
— OG6
C4B63_10g106 ⚠
kinesin
— OG6
C4B63_63g101 ⚠
Phosphatidylinositol 3-kinase tor1
— OG6
C4B63_49g160 ⚠
ATP-dependent DEAD/H RNA helicase
— OG6
C4B63_293g22 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_38g151 ⚠
tetratricopeptide repeat protein (TPR)
— OG6
C4B63_9g224 ⚠
Cilia- and flagella-associated protein 57
— OG6
C4B63_16g103 ⚠
conserved hypothetical protein
— OG6
C4B63_13g334
conserved hypothetical protein
— OG6
C4B63_8g48
dynein arm light chain
— OG6
C4B63_24g196 ⚠
microtubule-associated protein
— OG6
C4B63_17g276
TRAF3-interacting protein 1
— OG6
C4B63_10g105 ⚠
kinesin protein
— OG6
C4B63_63g98
ubiquitin-protein ligase
— OG6
C4B63_17g45
kinesin
— OG6
C4B63_293g23 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_4g103
intraflagellar transport protein 140
— OG6
C4B63_9g223 ⚠
Cilia- and flagella-associated protein 57
— OG6
C4B63_16g102 ⚠
conserved hypothetical protein
— OG6
C4B63_7g424 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG6
C4B63_24g194 ⚠
microtubule-associated protein
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.