C4B63_56g95

paraflagellar rod protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_134897 OG7: OG7_0037847 181 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 181 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_25g220 ⚠
5'-3' exoribonuclease B
— OG7
C4B63_4g480 ⚠
Flagellum attachment zone protein 7(fragment)
— OG6
C4B63_48g155 ⚠
conserved hypothetical protein
— OG6
C4B63_8g48 ⚠
dynein arm light chain
— Both
C4B63_58g144
Cilia- and flagella-associated protein 70
— Both
C4B63_45g70 ⚠
conserved hypothetical protein
— OG6
C4B63_127g30 ⚠
Flagellum attachment zone protein 14
— Both
C4B63_13g334
conserved hypothetical protein
— Both
C4B63_13g243
intraflagellar transport protein 122B(fragmen
— Both
C4B63_16g103 ⚠
conserved hypothetical protein
— Both
C4B63_1g57
AAA ATPase
— Both
C4B63_86g55 ⚠
Probable E3 ubiquitin-protein ligase HERC3
— OG6
C4B63_186g7 ⚠
cleavage and polyadenylation specificity fact
— Both
C4B63_18g325 ⚠
endosomal trafficking protein RME-8
— Both
C4B63_42g174
conserved hypothetical protein
— Both
C4B63_49g160 ⚠
ATP-dependent DEAD/H RNA helicase
— OG6
C4B63_18g72 ⚠
cyclosome subunit
— Both
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— Both
C4B63_52g40
immunodominant antigen
— Both
C4B63_35g116 ⚠
VPS13A C
— OG6
C4B63_21g49
conserved hypothetical protein
— Both
C4B63_45g69 ⚠
Dynein heavy chain 1, axonemal
— OG6
C4B63_85g63
Rab-GTPase-TBC domain containing protein
— Both
C4B63_38g151 ⚠
tetratricopeptide repeat protein (TPR)
— Both
C4B63_38g152 ⚠
tetratricopeptide repeat protein (TPR)
— Both
C4B63_23g242 ⚠
radial spoke protein RSP10
— Both
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— Both
C4B63_128g60
zinc-finger protein family member
— Both
C4B63_2g552 ⚠
inner dynein arm I1 intermediate chain, axone
— Both
C4B63_19g131
conserved hypothetical protein
— Both
C4B63_24g272 ⚠
Zn-finger in Ran binding protein and others/S
— Both
C4B63_24g273 ⚠
Probable E3 ubiquitin-protein ligase HERC1
— Both
C4B63_4g82 ⚠
conserved hypothetical protein
— Both
C4B63_25g316
inositol polyphosphate kinase-like protein
— Both
C4B63_102g33 ⚠
tyrosine protein kinase
— Both
C4B63_207g12 ⚠
leucine-rich repeat protein (LRRP)
— Both
C4B63_79g41 ⚠
tyrosine protein kinase
— Both
C4B63_4g83 ⚠
conserved hypothetical protein
— Both
C4B63_33g8 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— OG7
C4B63_29g3 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— OG7
C4B63_56g104 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— OG7
C4B63_22g288
Midasin
— OG7
C4B63_42g199 ⚠
conserved hypothetical protein
— OG7
C4B63_31g98
Autophagy protein Apg6
— OG7
C4B63_28g113 ⚠
dynein arm light chain
— OG7
C4B63_12g196
conserved hypothetical protein
— OG7
C4B63_21g61 ⚠
guanine nucleotide exchange factor subunit GC
— OG7
C4B63_13g297 ⚠
Axonemal inner arm dynein light chain
— OG7
C4B63_281g8 ⚠
translation initiation factor eIF2B delta sub
— OG7
C4B63_2g729 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.