C4B63_26g246

protein kinase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_156902 OG7: OG7_0000432 153 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 153 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_45g232 ⚠
ubiquitin-protein ligase-like
— OG6
C4B63_45g235 ⚠
ubiquitin-protein ligase-like
— OG6
C4B63_45g234 ⚠
ubiquitin-protein ligase-like
— OG6
C4B63_45g236 ⚠
ubiquitin-protein ligase
— OG6
C4B63_4g103
intraflagellar transport protein 140
— OG6
C4B63_3g241 ⚠
mucin TcMUC
— OG6
C4B63_86g55 ⚠
Probable E3 ubiquitin-protein ligase HERC3
— OG6
C4B63_186g7 ⚠
cleavage and polyadenylation specificity fact
— OG6
C4B63_18g325 ⚠
endosomal trafficking protein RME-8
— OG6
C4B63_49g160 ⚠
ATP-dependent DEAD/H RNA helicase
— OG6
C4B63_18g72 ⚠
cyclosome subunit
— OG6
C4B63_35g116 ⚠
VPS13A C
— OG6
C4B63_22g262c
DNA-directed RNA polymerase 2, RPB12 subunit
— OG6
C4B63_14g249
structural maintenance of chromosome 3
— OG6
C4B63_43g6 ⚠
T-complex protein 1, delta subunit
— OG6
C4B63_149g23
conserved hypothetical protein
— OG6
C4B63_52g35 ⚠
RNA editing 3' terminal uridylyl transferase
— OG6
C4B63_528g2 ⚠
RNA editing 3' terminal uridylyl transferase
— OG6
C4B63_43g135
proteasome alpha 2 subunit
— OG6
C4B63_528g3 ⚠
RNA editing 3' terminal uridylyl transferase
— OG6
C4B63_528g4 ⚠
RNA editing 3' terminal uridylyl transferase
— OG6
C4B63_168g37 ⚠
T-complex protein 1, delta subunit
— OG6
C4B63_9g523
U5 small nuclear ribonucleoprotein component
— OG6
C4B63_14g250
Anaphase-promoting complex subunit 3
— OG6
C4B63_28g113
dynein arm light chain
— OG6
C4B63_51g179
conserved hypothetical protein
— OG6
C4B63_89g51
FYVE zinc-finger containing protein
— OG6
C4B63_87g21 ⚠
conserved hypothetical protein
— OG6
C4B63_87g20 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG6
C4B63_56g95
paraflagellar rod protein
— OG6
C4B63_281g16 ⚠
intraflagellar transport protein 88
— OG6
C4B63_19g23 ⚠
intraflagellar transport protein 88
— OG6
C4B63_2g155 ⚠
PRP8 protein homologue
— OG6
C4B63_2g690
chaperonin alpha subunit
— OG6
C4B63_143g33 ⚠
inorganic polyphosphate/ATP-NAD kinase
— OG6
C4B63_2g154 ⚠
PRP8 protein homologue
— OG6
C4B63_30g176 ⚠
inorganic polyphosphate/ATP-NAD kinase
— OG6
C4B63_6g572 ⚠
5'-3' exoribonuclease A
— OG6
C4B63_3g494 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_4g431
intraflagellar transport protein 52
— OG6
C4B63_128g60
zinc-finger protein family member
— OG6
C4B63_162g33 ⚠
chaperonin TCP20
— OG6
C4B63_46g11 ⚠
chaperonin TCP20
— OG6
C4B63_252g22 ⚠
T-complex protein 1, beta subunit
— OG6
C4B63_2g485 ⚠
T-complex protein 1, beta subunit
— OG6
C4B63_11g73 ⚠
conserved hypothetical protein
— OG6
C4B63_11g72 ⚠
conserved hypothetical protein
— OG6
C4B63_12g396
proteasome alpha 7 subunit
— OG6
C4B63_2g302
proteasome alpha 1 subunit
— OG6
C4B63_52g147
conserved hypothetical protein
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.