C4B63_45g235

ubiquitin-protein ligase-like
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101783 OG7: OG7_0000785 138 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 138 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_4g103 ⚠
intraflagellar transport protein 140
— OG6
C4B63_26g246 ⚠
protein kinase
— OG6
C4B63_80g17 ⚠
ATP binding protein-like protein
— OG6
C4B63_293g23 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_17g45 ⚠
kinesin
— OG6
C4B63_149g16 ⚠
conserved hypothetical protein
— OG6
C4B63_45g71 ⚠
conserved hypothetical protein
— OG6
C4B63_2g826 ⚠
conserved hypothetical protein
— OG6
C4B63_25g218 ⚠
Centrosomal protein of 164 kDa
— OG6
C4B63_278g6 ⚠
endosomal trafficking protein RME-8
— OG6
C4B63_43g141 ⚠
conserved hypothetical protein
— OG6
C4B63_42g85 ⚠
conserved hypothetical protein
— OG6
C4B63_49g186 ⚠
ccr4-not transcription complex subunit
— OG6
C4B63_63g98 ⚠
ubiquitin-protein ligase
— OG6
C4B63_24g196 ⚠
microtubule-associated protein
— OG6
C4B63_17g276 ⚠
TRAF3-interacting protein 1
— OG6
C4B63_10g105 ⚠
kinesin protein
— OG6
C4B63_28g111 ⚠
synaptojanin
— OG6
C4B63_4g480 ⚠
Flagellum attachment zone protein 7(fragment)
— OG6
C4B63_8g48 ⚠
dynein arm light chain
— OG6
C4B63_58g144 ⚠
Cilia- and flagella-associated protein 70
— OG6
C4B63_45g70 ⚠
conserved hypothetical protein
— OG6
C4B63_13g334 ⚠
conserved hypothetical protein
— OG6
C4B63_127g30 ⚠
Flagellum attachment zone protein 14
— OG6
C4B63_16g103 ⚠
conserved hypothetical protein
— OG6
C4B63_13g243 ⚠
intraflagellar transport protein 122B(fragmen
— OG6
C4B63_25g219 ⚠
conserved hypothetical protein
— OG6
C4B63_1g57 ⚠
AAA ATPase
— OG6
C4B63_42g174 ⚠
conserved hypothetical protein
— OG6
C4B63_49g160 ⚠
ATP-dependent DEAD/H RNA helicase
— OG6
C4B63_18g325 ⚠
endosomal trafficking protein RME-8
— OG6
C4B63_186g7 ⚠
cleavage and polyadenylation specificity fact
— OG6
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG6
C4B63_52g40 ⚠
immunodominant antigen
— OG6
C4B63_45g69 ⚠
Dynein heavy chain 1, axonemal
— OG6
C4B63_21g49 ⚠
conserved hypothetical protein
— OG6
C4B63_12g396 ⚠
proteasome alpha 7 subunit
— OG6
C4B63_52g35 ⚠
RNA editing 3' terminal uridylyl transferase
— OG6
C4B63_528g2 ⚠
RNA editing 3' terminal uridylyl transferase
— OG6
C4B63_528g3 ⚠
RNA editing 3' terminal uridylyl transferase
— OG6
C4B63_528g4 ⚠
RNA editing 3' terminal uridylyl transferase
— OG6
C4B63_252g22 ⚠
T-complex protein 1, beta subunit
— OG6
C4B63_2g485 ⚠
T-complex protein 1, beta subunit
— OG6
C4B63_11g73 ⚠
conserved hypothetical protein
— OG6
C4B63_11g72 ⚠
conserved hypothetical protein
— OG6
C4B63_163g31 ⚠
conserved hypothetical protein
— OG6
C4B63_70g80 ⚠
proteasome alpha 7 subunit
— OG6
C4B63_149g23 ⚠
conserved hypothetical protein
— OG6
C4B63_20g172 ⚠
chaperonin alpha subunit
— OG6
C4B63_4g431 ⚠
intraflagellar transport protein 52
— OG6
Page 1 of 3
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.