C4B63_28g47

Serine/threonine-protein phosphatase 4 regulatory subunit 4
Trypanosoma cruzi Dm28c 2018 OG6: OG6_105675 OG7: OG7_0009082 59 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 59 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_56g58 ⚠
ankyrin,
— OG7
C4B63_7g173 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_7g169 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_7g161 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_2g785
conserved hypothetical protein
— Both
C4B63_20g6 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_63g95 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_148g30 ⚠
conserved hypothetical protein
— Both
C4B63_87g16 ⚠
pitrilysin-like metalloprotease
— Both
C4B63_297g16 ⚠
cholinephosphate cytidylyltransferase A
— Both
C4B63_102g71 ⚠
Programmed cell death protein 2, C-terminal d
— Both
C4B63_24g246 ⚠
kynureninase
— Both
C4B63_212g12 ⚠
anion-transporting ATPase-like
— Both
C4B63_9g323
conserved hypothetical protein
— Both
C4B63_9g293 ⚠
Mitochondrial-processing peptidase subunit al
— Both
C4B63_16g30 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_4g244 ⚠
ankyrin repeat family protein
— OG7
C4B63_7g323 ⚠
conserved hypothetical protein
— OG7
C4B63_4g272 ⚠
cholinephosphate cytidylyltransferase A
— OG7
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_6g521 ⚠
DIS3-like exonuclease
— OG7
C4B63_2g74 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_2g828 ⚠
ankyrin repeat protein
— OG7
C4B63_2g352 ⚠
nucleolar GTP-binding protein 1(fragment)
— OG7
C4B63_2g75 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_7g324 ⚠
Programmed cell death protein 2, C-terminal d
— OG7
C4B63_263g16 ⚠
Programmed cell death protein 2-like
— OG7
C4B63_58g112 ⚠
mitochondrial processing peptidase alpha subu
— OG7
C4B63_95g34 ⚠
mitochondrial processing peptidase alpha subu
— OG7
C4B63_51g96
UPF0301 protein BT 1078
— Both
C4B63_2g70
conserved hypothetical protein
— Both
C4B63_160g6 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_30g129 ⚠
rrp44p homologue
— Both
C4B63_8g494
Protein ApaG
— Both
C4B63_147g45 ⚠
kynureninase
— Both
C4B63_70g101
conserved hypothetical protein
— Both
C4B63_4g234 ⚠
5-oxoprolinase
— Both
C4B63_2g362
conserved hypothetical protein
— Both
C4B63_20g11 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_20g10 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_17g71 ⚠
cholinephosphate cytidylyltransferase A
— Both
C4B63_17g239 ⚠
conserved hypothetical protein
— Both
C4B63_44g214
conserved hypothetical protein
— Both
C4B63_7g165 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_32g22
Uncharacterized WD repeat-containing protein
— Both
C4B63_11g71
conserved hypothetical protein
— Both
C4B63_20g3 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
C4B63_4g356
RNA-binding protein 29
— Both
C4B63_4g235 ⚠
5-oxoprolinase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.