C4B63_14g216

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_108229 OG7: OG7_0012620 52 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 52 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_2g41 ⚠
Protein kinase domain
— OG7
C4B63_63g95 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_63g30
Histone-lysine N-methyltransferase ATXR2
— OG6
C4B63_21g76
Adenosine deaminase-like protein
— Both
C4B63_40g159
translation initiation factor 2 subunit
— Both
C4B63_17g239 ⚠
conserved hypothetical protein
— Both
C4B63_148g30 ⚠
conserved hypothetical protein
— Both
C4B63_18g280 ⚠
conserved hypothetical protein
— OG7
C4B63_10g286 ⚠
diphthamide synthesis protein
— OG7
C4B63_2g74 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_2g75 ⚠
poly(A)-specific ribonuclease PARN(fragment)
— OG7
C4B63_23g150 ⚠
diphthamide synthesis protein
— OG7
C4B63_70g84 ⚠
serine/threonine protein kinase
— OG7
C4B63_16g30 ⚠
poly(A)-specific ribonuclease PARN
— Both
C4B63_70g82 ⚠
protein kinase
— OG7
C4B63_2g833 ⚠
Probable C-terminal domain small phosphatase
— OG7
C4B63_11g24 ⚠
TFIIF-stimulated CTD phosphatase
— OG7
C4B63_48g7 ⚠
NLI interacting factor-like phosphatase
— OG7
C4B63_23g189 ⚠
Uncharacterized protein C2F7.02c
— OG7
C4B63_54g5 ⚠
TFIIF-stimulated CTD phosphatase
— OG7
C4B63_63g31 ⚠
Carboxy-terminal domain RNA polymerase II pol
— OG7
C4B63_301g7 ⚠
conserved hypothetical protein
— OG7
C4B63_44g246 ⚠
nucleolar protein
— OG7
C4B63_9g484 ⚠
5-methylcytosine rRNA methyltransferase NSUN4
— OG7
C4B63_6g420 ⚠
Probable 28S rRNA (cytosine-C(5))-methyltrans
— OG7
C4B63_23g124 ⚠
NOL1/NOP2/sun family
— OG7
C4B63_21g89
conserved hypothetical protein
— Both
C4B63_429g2 ⚠
leucine-rich repeat-containing protein
— Both
C4B63_19g266 ⚠
conserved hypothetical protein
— Both
C4B63_232g18
exosome complex exonuclease
— Both
C4B63_19g265 ⚠
F-box protein dre-1
— Both
C4B63_4g228
conserved hypothetical protein
— Both
C4B63_48g96
conserved hypothetical protein
— Both
C4B63_25g325 ⚠
conserved hypothetical protein
— Both
C4B63_19g267 ⚠
Right handed beta helix region containing pro
— Both
C4B63_244g1 ⚠
conserved hypothetical protein
— Both
C4B63_11g10
KIF1-binding protein
— Both
C4B63_11g99 ⚠
Putative methyltransferase NSUN6
— Both
C4B63_107g3 ⚠
Putative methyltransferase NSUN6
— Both
C4B63_23g85 ⚠
leucine-rich repeat-containing protein
— Both
C4B63_79g23 ⚠
conserved hypothetical protein
— Both
C4B63_51g86
conserved hypothetical protein
— Both
C4B63_32g225
3-hydroxy-3-methylglutaryl-CoA synthase
— Both
C4B63_6g113
ribonucleoside-diphosphate reductase large ch
— Both
C4B63_18g142
conserved hypothetical protein
— Both
C4B63_2g388
conserved hypothetical protein
— Both
C4B63_187g35 ⚠
protein kinase
— Both
C4B63_187g34 ⚠
protein kinase
— Both
C4B63_32g322 ⚠
protein kinase
— Both
C4B63_160g6 ⚠
poly(A)-specific ribonuclease PARN
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.