C4B63_244g1

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_158040 OG7: OG7_0051920 44 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 44 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_4g265 ⚠
pre-RNA processing PIH1/Nop17
— OG7
C4B63_63g101 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
C4B63_22g113 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_7g424 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_2g215 ⚠
PIH1 domain-containing protein 1
— OG7
C4B63_30g206 ⚠
conserved hypothetical protein
— Both
C4B63_23g143 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_10g280 ⚠
dihydrolipoamide dehydrogenase
— OG7
C4B63_137g47 ⚠
receptor for activated C kinase 1
— OG7
C4B63_137g46 ⚠
receptor for activated C kinase 1
— OG7
C4B63_18g20 ⚠
Protein will die slowly
— OG7
C4B63_137g48 ⚠
receptor for activated C kinase 1
— OG7
C4B63_137g44 ⚠
receptor for activated C kinase 1
— OG7
C4B63_6g320 ⚠
receptor for activated C kinase 1
— OG7
C4B63_6g321 ⚠
receptor for activated C kinase 1
— OG7
C4B63_137g45 ⚠
receptor for activated C kinase 1
— OG7
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— Both
C4B63_48g96 ⚠
conserved hypothetical protein
— Both
C4B63_14g216 ⚠
conserved hypothetical protein
— Both
C4B63_40g114 ⚠
glycosyl hydrolase
— Both
C4B63_84g22 ⚠
conserved hypothetical protein
— Both
C4B63_84g21 ⚠
conserved hypothetical protein
— Both
C4B63_80g31 ⚠
Dynein assembly factor 4, axonemal
— Both
C4B63_19g266 ⚠
conserved hypothetical protein
— Both
C4B63_4g228 ⚠
conserved hypothetical protein
— Both
C4B63_19g265 ⚠
F-box protein dre-1
— Both
C4B63_19g267 ⚠
Right handed beta helix region containing pro
— Both
C4B63_113g53 ⚠
trans-splicing factor
— Both
C4B63_249g22 ⚠
dihydrolipoamide dehydrogenase
— Both
C4B63_326g15 ⚠
dihydrolipoamide dehydrogenase
— Both
C4B63_97g31 ⚠
NADH-ubiquinone oxidoreductase complex I subu
— Both
C4B63_358g1 ⚠
dihydrolipoamide dehydrogenase
— Both
C4B63_249g23 ⚠
dihydrolipoamide dehydrogenase
— Both
C4B63_326g16 ⚠
dihydrolipoamide dehydrogenase
— Both
C4B63_43g214 ⚠
U4/U6 small nuclear ribonuclear protein
— Both
C4B63_232g18 ⚠
exosome complex exonuclease
— Both
C4B63_25g310 ⚠
conserved hypothetical protein
— Both
C4B63_4g264 ⚠
Protein kintoun
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.