C4B63_16g147

Ring finger domain containing protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_156425 OG7: OG7_0000431 22 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 22 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_28g91 ⚠
Kinesin-13 3
— OG6
C4B63_4g181 ⚠
Sestrin-3
— OG6
C4B63_18g68 ⚠
Zinc finger protein 277
— OG6
C4B63_35g171 ⚠
tRNA (guanine(37)-N1)-methyltransferase 1
— OG6
C4B63_32g18 ⚠
protein kinase
— OG6
C4B63_34g118 ⚠
conserved hypothetical protein
— OG6
C4B63_109g37 ⚠
Gar1/Naf1 RNA binding region containing prote
— OG6
C4B63_18g222 ⚠
Ubiquitin carboxyl-terminal hydrolase MINDY-1
— OG6
C4B63_20g55 ⚠
Ribosome maturation protein SBDS
— OG6
C4B63_163g28 ⚠
conserved hypothetical protein
— OG6
C4B63_9g308 ⚠
ubiquitin activating enzyme
— OG6
C4B63_23g131 ⚠
protein farnesyltransferase alpha subunit
— OG6
C4B63_17g98 ⚠
E3 ubiquitin-protein ligase UPL3
— OG6
C4B63_22g94 ⚠
cyclophilin 15
— OG6
C4B63_13g295 ⚠
pumilio/PUF RNA binding protein 6
— OG6
C4B63_97g23 ⚠
pumilio/PUF RNA binding protein 2
— OG6
C4B63_204g19 ⚠
pumilio/PUF RNA binding protein 6
— OG6
C4B63_16g11 ⚠
5'-AMP-activated protein kinase subunit beta
— OG6
C4B63_314g10 ⚠
5'-AMP-activated protein kinase subunit beta
— OG6
C4B63_2g376 ⚠
ribosome assembly protein RRB1
— OG6
C4B63_18g32 ⚠
pseudouridine synthase A-like protein
— OG6
C4B63_18g147 ⚠
calmodulin
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.