C4B63_2g567

mRNA export factor MEX67
Trypanosoma cruzi Dm28c 2018 OG6: OG6_145561 OG7: OG7_0027177 94 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 94 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_12g22 ⚠
conserved hypothetical protein
— OG7
C4B63_114g1 ⚠
N-acetyltransferase
— OG7
C4B63_25g188 ⚠
Phosphorylated CTD interacting factor 1 WW do
— OG7
C4B63_4g63 ⚠
polyprenyl synthase
— OG7
C4B63_25g257 ⚠
zinc-finger protein ZPR1
— OG7
C4B63_11g473 ⚠
DNL-type zinc finger protein
— OG7
C4B63_101g36 ⚠
inositol-3-phosphate synthase
— OG7
C4B63_355g19 ⚠
inositol-3-phosphate synthase(fragment)
— OG7
C4B63_25g241 ⚠
conserved hypothetical protein
— OG7
C4B63_35g171 ⚠
tRNA (guanine(37)-N1)-methyltransferase 1
— OG7
C4B63_206g3 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_47g96 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_51g180 ⚠
N-acetyltransferase complex ARD1 subunit
— OG7
C4B63_93g64 ⚠
amidohydrolase
— OG7
C4B63_93g65 ⚠
amidohydrolase
— OG7
C4B63_2g431 ⚠
GTPase protein
— OG7
C4B63_128g61 ⚠
50S ribosome-binding GTPase
— OG7
C4B63_128g62 ⚠
50S ribosome-binding GTPase
— OG7
C4B63_2g345 ⚠
GTP-binding protein
— OG7
C4B63_91g35 ⚠
GTPase
— OG7
C4B63_8g202 ⚠
GTP-binding protein
— OG7
C4B63_56g32 ⚠
GTPase
— OG7
C4B63_128g63 ⚠
GTP-binding protein
— OG7
C4B63_85g64 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
C4B63_7g67 ⚠
Sec7 guanine-nucleotide exchange factor
— OG7
C4B63_30g203 ⚠
conserved hypothetical protein
— OG7
C4B63_8g522 ⚠
conserved hypothetical protein
— OG7
C4B63_17g63 ⚠
CYC2-like cyclin(fragment)
— OG7
C4B63_19g86 ⚠
CYC2-like cyclin 6
— OG7
C4B63_32g257 ⚠
Cyclin-U3-1
— OG7
C4B63_32g259 ⚠
Cyclin-U4-1
— OG7
C4B63_18g174 ⚠
cyclin
— OG7
C4B63_56g69 ⚠
CYC2-like cyclin
— OG7
C4B63_297g7 ⚠
CYC2-like cyclin(fragment)
— OG7
C4B63_243g9 ⚠
CYC2-like cyclin
— OG7
C4B63_7g68 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_12g220 ⚠
pyruvate phosphate dikinase
— OG7
C4B63_21g298c ⚠
nuclear transport factor 2
— OG7
C4B63_7g56 ⚠
Protein transport protein sec71
— OG7
C4B63_81g15 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_7g57 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG7
C4B63_7g55 ⚠
conserved hypothetical protein
— OG7
C4B63_81g14 ⚠
guanine-nucleotide exchange factor, Sec7
— OG7
C4B63_72g98 ⚠
RNA pseudouridylate synthase protein
— OG7
C4B63_83g79 ⚠
RNA pseudouridylate synthase
— OG7
C4B63_8g52 ⚠
tRNA pseudouridine(31) synthase
— OG7
C4B63_76g60 ⚠
N-acetyltransferase
— OG7
C4B63_34g156 ⚠
Acyl-CoA-binding domain-containing protein 4
— OG7
C4B63_20g12 ⚠
Vacuolar protein sorting-associated protein 2
— OG7
C4B63_14g19 ⚠
flagellum transition zone component
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.