C4B63_16g19

5'-3' exoribonuclease C
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146922 OG7: OG7_0044562 72 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 72 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_10g524 ⚠
nuclear transcription factor
— OG7
C4B63_17g50 ⚠
Outer row dynein-assembly protein 7
— OG7
C4B63_157g19 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_41g128 ⚠
conserved hypothetical protein
— OG7
C4B63_224g16 ⚠
conserved hypothetical protein
— OG7
C4B63_41g122 ⚠
conserved hypothetical protein
— OG7
C4B63_41g125 ⚠
conserved hypothetical protein
— OG7
C4B63_41g119 ⚠
conserved hypothetical protein
— OG7
C4B63_30g245
conserved hypothetical protein
— OG7
C4B63_171g22 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_57g94 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_78g11 ⚠
conserved hypothetical protein
— OG7
C4B63_78g12 ⚠
conserved hypothetical protein
— OG7
C4B63_234g11 ⚠
conserved hypothetical protein
— OG7
C4B63_78g9 ⚠
conserved hypothetical protein
— OG7
C4B63_78g13 ⚠
Proteasome activator complex subunit 4
— OG7
C4B63_78g10 ⚠
conserved hypothetical protein
— OG7
C4B63_63g81 ⚠
protein transport protein Sec23A
— OG7
C4B63_61g82 ⚠
Chromosome transmission fidelity protein 18 h
— OG7
C4B63_39g340 ⚠
replication factor C, subunit 4
— OG7
C4B63_330g12 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_513g4 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_6g269 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
C4B63_18g277 ⚠
replication factor C, subunit 2
— OG7
C4B63_2g551 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_25g219 ⚠
conserved hypothetical protein
— OG7
C4B63_40g163 ⚠
leucine-rich repeat protein (LRRP)
— OG7
C4B63_2g762 ⚠
replication factor C, subunit 3
— OG7
C4B63_22g108 ⚠
Replication Factor C Subunit 1-related protei
— OG7
C4B63_4g577 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_63g41 ⚠
replication factor C, subunit 3
— OG7
C4B63_61g81 ⚠
conserved hypothetical protein
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_2g297
conserved hypothetical protein
— Both
C4B63_2g435
Flagellum attachment zone protein 12
— Both
C4B63_6g400 ⚠
conserved hypothetical protein
— Both
C4B63_2g553
Programmed cell death 6-interacting protein
— Both
C4B63_28g129 ⚠
replication factor C, subunit 1
— Both
C4B63_32g239 ⚠
tubulin folding cofactor D
— Both
C4B63_42g204 ⚠
Eukaryotic translation initiation factor 4E-4
— Both
C4B63_9g322
translation initiation factor IF-2
— Both
C4B63_42g205 ⚠
Eukaryotic translation initiation factor 4E-4
— Both
C4B63_2g368
conserved hypothetical protein
— Both
C4B63_42g187
conserved hypothetical protein
— Both
C4B63_82g92 ⚠
conserved hypothetical protein
— Both
C4B63_77g26 ⚠
conserved hypothetical protein
— Both
C4B63_23g275 ⚠
ATP-dependent DEAD/H RNA helicase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.