C4B63_12g315

Nuclear protein localization protein 4 homolog
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101880 OG7: OG7_0007128 172 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 172 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_13g109 ⚠
protein phosphatase 2C-like
— OG6
C4B63_17g249 ⚠
protein phosphatase 2C
— OG6
C4B63_184g9 ⚠
protein phosphatase 2C
— OG6
C4B63_6g395 ⚠
Elongation factor G 2, mitochondrial
— OG7
C4B63_47g40 ⚠
CS domain containing protein
— Both
C4B63_2g235 ⚠
Co-chaperone protein P23
— Both
C4B63_20g212 ⚠
enoyl-CoA hydratase/isomerase family protein
— Both
C4B63_20g213 ⚠
enoyl-CoA hydratase/isomerase family protein
— Both
C4B63_27g188 ⚠
conserved hypothetical protein
— Both
C4B63_18g278 ⚠
RNA-binding protein
— OG6
C4B63_253g15 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_54g69 ⚠
aspartate aminotransferase
— Both
C4B63_6g146 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_28g64 ⚠
aspartate aminotransferase
— Both
C4B63_6g148 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_10g148 ⚠
carnitine/choline acetyltransferase
— OG6
C4B63_10g147 ⚠
carnitine O-acetyltransferase(fragment)
— OG6
C4B63_17g73 ⚠
Probable protein phosphatase methylesterase 1
— Both
C4B63_18g30 ⚠
epsilon-adaptin
— Both
C4B63_297g19 ⚠
Protein phosphatase methylesterase 1
— Both
C4B63_7g361 ⚠
phosphomannomutase-like protein
— Both
C4B63_17g188 ⚠
Phosphopantetheine adenylyltransferase
— Both
C4B63_30g144 ⚠
Cilia- and flagella-associated protein 52
— Both
C4B63_30g145 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
C4B63_16g163 ⚠
Pyridoxal phosphate homeostasis protein
— Both
C4B63_114g23 ⚠
UBX domain-containing protein 3
— Both
C4B63_23g200 ⚠
Flagellum attachment zone protein 19
— Both
C4B63_6g385 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
C4B63_230g26 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
C4B63_69g27 ⚠
35 kDa cyclophilin
— OG6
C4B63_14g176 ⚠
ATP-dependent DEAD/H RNA helicase
— Both
C4B63_163g32 ⚠
rac serine-threonine kinase
— OG6
C4B63_14g193 ⚠
PSP1 C-terminal conserved region
— OG6
C4B63_14g175 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— Both
C4B63_81g41 ⚠
Suppressor of disruption of TFIIS
— Both
C4B63_6g430 ⚠
conserved hypothetical protein
— Both
C4B63_14g192 ⚠
PSP1 C-terminal conserved region
— OG6
C4B63_30g274 ⚠
rac serine-threonine kinase
— OG6
C4B63_44g252 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_279g8 ⚠
ubiquitin carboxyl-terminal hydrolase
— Both
C4B63_19g259 ⚠
conserved hypothetical protein
— Both
C4B63_48g23 ⚠
nicotinate phosphoribosyltransferase
— Both
C4B63_9g331 ⚠
transcription elongation factor s-II
— Both
C4B63_23g248 ⚠
inorganic pyrophosphatase
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_16g91 ⚠
Bis(5'-adenosyl)-triphosphatase
— Both
C4B63_25g220 ⚠
5'-3' exoribonuclease B
— OG7
C4B63_112g33 ⚠
haloacid dehalogenase hydrolase
— OG7
C4B63_30g112 ⚠
haloacid dehalogenase hydrolase
— OG7
C4B63_27g9 ⚠
conserved hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.