C4B63_2g564

mRNA export factor MEX67
Trypanosoma cruzi Dm28c 2018 OG6: OG6_143364 OG7: OG7_0027177 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_30g203 ⚠
conserved hypothetical protein
— Both
C4B63_32g257 ⚠
Cyclin-U3-1
— Both
C4B63_26g317 ⚠
Alanyl-tRNA editing protein Aarsd1-B
— Both
C4B63_136g36 ⚠
Alanyl-tRNA editing protein Aarsd1
— Both
C4B63_136g37 ⚠
tRNA synthetases class II (A)/Threonyl and Al
— Both
C4B63_128g53 ⚠
serine/threonine protein phosphatase
— OG6
C4B63_27g214 ⚠
serine/threonine protein phosphatase
— OG6
C4B63_87g21 ⚠
conserved hypothetical protein
— Both
C4B63_87g20 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— Both
C4B63_2g567 ⚠
mRNA export factor MEX67
— Both
C4B63_128g54 ⚠
phosphoprotein phosphatase
— OG6
C4B63_12g220 ⚠
pyruvate phosphate dikinase
— Both
C4B63_12g221 ⚠
pyruvate phosphate dikinase
— Both
C4B63_193g9 ⚠
metallo-peptidase, Clan MF, Family M17
— +1 more Both
C4B63_70g129 ⚠
metallo-peptidase, Clan MF, Family M17
— +1 more Both
C4B63_12g153 ⚠
metallo-peptidase, Clan MF, Family M17
— +1 more Both
C4B63_128g63 ⚠
GTP-binding protein
— Both
C4B63_128g62 ⚠
50S ribosome-binding GTPase
— Both
C4B63_128g61 ⚠
50S ribosome-binding GTPase
— Both
C4B63_25g241 ⚠
conserved hypothetical protein
— Both
C4B63_25g257 ⚠
zinc-finger protein ZPR1
— Both
C4B63_27g1 ⚠
acyl-CoA binding protein
— Both
C4B63_122g18 ⚠
acyl-CoA binding protein
— Both
C4B63_51g180 ⚠
N-acetyltransferase complex ARD1 subunit
— Both
C4B63_8g52 ⚠
tRNA pseudouridine(31) synthase
— Both
C4B63_30g129 ⚠
rrp44p homologue
— Both
C4B63_2g243 ⚠
conserved hypothetical protein
— Both
C4B63_18g29 ⚠
phosphopantothenoylcysteine decarboxylase
— Both
C4B63_23g103
cdc2-related kinase 1
— OG6
C4B63_2g244 ⚠
conserved hypothetical protein
— Both
C4B63_18g79 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_2g450 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
C4B63_20g12 ⚠
Vacuolar protein sorting-associated protein 2
— Both
C4B63_18g78 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_42g201 ⚠
conserved hypothetical protein
— Both
C4B63_2g66
helicase
— OG6
C4B63_18g219 ⚠
tRNA methyltransferase 10 homolog A
— Both
C4B63_8g522 ⚠
conserved hypothetical protein
— Both
C4B63_85g64 ⚠
DNA-damage inducible protein DDI1-like protei
— Both
C4B63_25g188 ⚠
Phosphorylated CTD interacting factor 1 WW do
— Both
C4B63_51g110 ⚠
Importin beta-like SAD2
— Both
C4B63_101g36 ⚠
inositol-3-phosphate synthase
— Both
C4B63_355g19 ⚠
inositol-3-phosphate synthase(fragment)
— Both
C4B63_12g22 ⚠
conserved hypothetical protein
— Both
C4B63_35g171 ⚠
tRNA (guanine(37)-N1)-methyltransferase 1
— Both
C4B63_57g115 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
C4B63_28g150 ⚠
pre-mRNA-splicing factor ATP-dependent RNA he
— OG6
C4B63_3g1119 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
C4B63_93g65 ⚠
amidohydrolase
— Both
C4B63_93g64 ⚠
amidohydrolase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.