C4B63_2g243

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_108008 OG7: OG7_0013020 250 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 250 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_6g521 ⚠
DIS3-like exonuclease
— +1 more Both
C4B63_30g129 ⚠
rrp44p homologue
— Both
C4B63_355g19 ⚠
inositol-3-phosphate synthase(fragment)
— Both
C4B63_19g179 ⚠
protein kinase
— Both
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_101g36 ⚠
inositol-3-phosphate synthase
— Both
C4B63_271g80c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
C4B63_2g1123c ⚠
small nuclear ribonucleoprotein Sm-F
— OG7
C4B63_144g102c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
C4B63_69g174c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
C4B63_206g3 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_47g96 ⚠
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminoc
— OG7
C4B63_20g49 ⚠
conserved hypothetical protein
— OG7
C4B63_3g864 ⚠
Mucin-associated surface protein (MASP)
— OG7
C4B63_14g27 ⚠
flagellum transition zone component
— OG7
C4B63_14g19 ⚠
flagellum transition zone component
— OG7
C4B63_2g431 ⚠
GTPase protein
— OG7
C4B63_2g345 ⚠
GTP-binding protein
— OG7
C4B63_91g35 ⚠
GTPase
— OG7
C4B63_8g202 ⚠
GTP-binding protein
— OG7
C4B63_56g32 ⚠
GTPase
— OG7
C4B63_45g221 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_21g245 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_207g22 ⚠
ATP-dependent RNA helicase HEL67
— OG7
C4B63_31g58 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_4g90 ⚠
ATP-dependent RNA helicase HEL67
— OG7
C4B63_81g40 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_94g58 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_2g567 ⚠
mRNA export factor MEX67
— OG7
C4B63_348g23 ⚠
cytochrome b5
— OG7
C4B63_25g1526c ⚠
Acyl-lipid (8-3)-desaturase
— OG7
C4B63_10g403 ⚠
cytochrome b5
— OG7
C4B63_8g211 ⚠
cytochrome b
— OG7
C4B63_1g121c ⚠
cytochrome b5-like protein
— OG7
C4B63_70g572c ⚠
cytochrome b5
— OG7
C4B63_122g20 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
C4B63_11g473 ⚠
DNL-type zinc finger protein
— Both
C4B63_56g85 ⚠
conserved hypothetical protein
— Both
C4B63_56g84 ⚠
conserved hypothetical protein
— Both
C4B63_34g118 ⚠
conserved hypothetical protein
— Both
C4B63_109g37 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
C4B63_93g64 ⚠
amidohydrolase
— Both
C4B63_93g65 ⚠
amidohydrolase
— Both
C4B63_49g166 ⚠
alanyl-tRNA synthetase
— Both
C4B63_49g164 ⚠
alanyl-tRNA synthetase
— Both
C4B63_19g137 ⚠
cleavage and polyadenylation specificity fact
— Both
C4B63_49g165 ⚠
alanyl-tRNA synthetase
— Both
C4B63_14g97 ⚠
isoleucyl-tRNA synthetase
— Both
C4B63_20g12 ⚠
Vacuolar protein sorting-associated protein 2
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.