C4B63_21g264

protein transport protein SEC23
Trypanosoma cruzi Dm28c 2018 OG6: OG6_147026 OG7: OG7_0004996 164 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 164 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_41g125 ⚠
conserved hypothetical protein
— OG7
C4B63_21g261 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
C4B63_19g185 ⚠
isocitrate dehydrogenase
— Both
C4B63_7g59 ⚠
protein phosphatase 2C
— OG6
C4B63_7g58 ⚠
protein phosphatase 2C
— OG6
C4B63_31g99 ⚠
WD repeat-containing protein 17
— Both
C4B63_114g23 ⚠
UBX domain-containing protein 3
— Both
C4B63_13g192 ⚠
Elongation factor G1, mitochondrial
— Both
C4B63_14g183 ⚠
mitochondrial intermediate peptidase
— Both
C4B63_3g1122 ⚠
choline/ethanolamine kinase
— Both
C4B63_3g1118 ⚠
choline/ethanolamine kinase
— Both
C4B63_4g189 ⚠
alcohol dehydrogenase
— Both
C4B63_11g76 ⚠
molecular chaperone HscB
— Both
C4B63_4g226 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— Both
C4B63_2g522 ⚠
choline kinase
— OG7
C4B63_267g6 ⚠
protein transport protein Sec24C(fragment)
— OG7
C4B63_12g309 ⚠
protein transport protein Sec24C
— OG7
C4B63_10g497 ⚠
protein transport protein Sec24C
— OG7
C4B63_10g494 ⚠
thymine-7-hydroxylase
— OG7
C4B63_282g13 ⚠
Elongation factor G 2, mitochondrial
— OG7
C4B63_6g395 ⚠
Elongation factor G 2, mitochondrial
— OG7
C4B63_6g234 ⚠
Elongation factor G 2, mitochondrial
— OG7
C4B63_56g50 ⚠
Surp module,
— OG7
C4B63_56g51 ⚠
RNA-binding protein
— OG7
C4B63_157g19 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_17g50 ⚠
Outer row dynein-assembly protein 7
— OG7
C4B63_171g22 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_8g52 ⚠
tRNA pseudouridine(31) synthase
— OG7
C4B63_61g81 ⚠
conserved hypothetical protein
— OG7
C4B63_6g252 ⚠
Centrosomal protein of 164 kDa
— OG7
C4B63_8g527 ⚠
pseudouridylate synthase I
— OG7
C4B63_63g41 ⚠
replication factor C, subunit 3
— OG7
C4B63_21g245 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_41g119 ⚠
conserved hypothetical protein
— OG7
C4B63_4g577 ⚠
eukaryotic translation initiation factor 4E (
— OG7
C4B63_22g108 ⚠
Replication Factor C Subunit 1-related protei
— OG7
C4B63_2g782 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_2g762 ⚠
replication factor C, subunit 3
— OG7
C4B63_25g219 ⚠
conserved hypothetical protein
— OG7
C4B63_78g9 ⚠
conserved hypothetical protein
— OG7
C4B63_78g13 ⚠
Proteasome activator complex subunit 4
— OG7
C4B63_78g10 ⚠
conserved hypothetical protein
— OG7
C4B63_17g182 ⚠
phosphatidylinositol 3-kinase catalytic subun
— OG7
C4B63_10g524 ⚠
nuclear transcription factor
— OG7
C4B63_47g49 ⚠
tRNA pseudouridine synthase 1
— OG7
C4B63_45g221 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_330g12 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.