C4B63_4g494

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_109594 OG7: OG7_0013700 22 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 22 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_83g79 ⚠
RNA pseudouridylate synthase
— Both
C4B63_72g98 ⚠
RNA pseudouridylate synthase protein
— OG7
C4B63_8g52 ⚠
tRNA pseudouridine(31) synthase
— OG7
C4B63_63g81 ⚠
protein transport protein Sec23A
— OG7
C4B63_56g51 ⚠
RNA-binding protein
— OG7
C4B63_56g50 ⚠
Surp module,
— OG7
C4B63_17g182
phosphatidylinositol 3-kinase catalytic subun
— OG7
C4B63_47g49 ⚠
tRNA pseudouridine synthase 1
— OG7
C4B63_4g514 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
C4B63_8g527 ⚠
pseudouridylate synthase I
— OG7
C4B63_4g181
Sestrin-3
— Both
C4B63_21g264 ⚠
protein transport protein SEC23
— Both
C4B63_42g49
Protein aardvark
— Both
C4B63_44g113 ⚠
conserved hypothetical protein
— Both
C4B63_18g32 ⚠
pseudouridine synthase A-like protein
— Both
C4B63_22g94
cyclophilin 15
— Both
C4B63_58g128
conserved hypothetical protein
— Both
C4B63_44g114 ⚠
conserved hypothetical protein
— Both
C4B63_22g77
conserved hypothetical protein
— Both
C4B63_45g129 ⚠
conserved hypothetical protein
— Both
C4B63_45g130 ⚠
conserved hypothetical protein
— Both
C4B63_45g128 ⚠
conserved hypothetical protein
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.