C4B63_2g336

Proteinaceous RNase P 2
Trypanosoma cruzi Dm28c 2018 OG6: OG6_142709 OG7: OG7_0008141 22 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 22 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_8g520 ⚠
DNA polymerase sigma-like protein
— OG7
C4B63_6g115 ⚠
endonuclease/exonuclease/phosphatase
— OG7
C4B63_6g116 ⚠
endonuclease/exonuclease/phosphatase
— OG7
C4B63_28g211 ⚠
translation initiation factor IF-2
— OG7
C4B63_28g210 ⚠
translation initiation factor IF-2
— OG7
C4B63_216g37 ⚠
translation initiation factor IF-2
— OG7
C4B63_49g80 ⚠
translation initiation factor IF-2
— OG7
C4B63_32g9 ⚠
translation initiation factor IF-2
— OG7
C4B63_28g212 ⚠
translation initiation factor IF-2
— OG7
C4B63_38g158 ⚠
Poly(A) RNA polymerase cid14
— OG7
C4B63_45g105 ⚠
DNA polymerase sigma
— OG7
C4B63_137g49 ⚠
conserved hypothetical protein
— Both
C4B63_271g10 ⚠
conserved hypothetical protein
— OG7
C4B63_2g376 ⚠
ribosome assembly protein RRB1
— OG7
C4B63_43g202 ⚠
hook complex protein, conserved
— OG7
C4B63_49g81 ⚠
translation initiation factor IF-2
— Both
C4B63_28g57 ⚠
E3 ubiquitin-protein ligase listerin
— Both
C4B63_7g88 ⚠
2',5'-phosphodiesterase 12
— Both
C4B63_391g10 ⚠
conserved hypothetical protein
— Both
C4B63_84g58 ⚠
conserved hypothetical protein
— Both
C4B63_6g322 ⚠
conserved hypothetical protein
— Both
C4B63_4g140 ⚠
conserved hypothetical protein
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.