C4B63_52g157

serine hydroxymethyltransferase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100262 OG7: OG7_0003031 164 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 164 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_54g28
conserved hypothetical protein
— Both
C4B63_52g138
proline racemase
— OG6
C4B63_184g38 ⚠
TPR-repeat protein
— OG6
C4B63_13g167 ⚠
stress-inducible protein STI1-like
— OG6
C4B63_175g8 ⚠
TPR-repeat protein
— OG6
C4B63_23g110 ⚠
UDP-glucose:glycoprotein glucosyltransferase
— Both
C4B63_23g109 ⚠
UDP-glucose:glycoprotein glucosyltransferase
— Both
C4B63_93g69
tRNA (Uracil-5-)-methyltransferase
— Both
C4B63_49g164 ⚠
alanyl-tRNA synthetase
— Both
C4B63_19g137 ⚠
cleavage and polyadenylation specificity fact
— Both
C4B63_49g165 ⚠
alanyl-tRNA synthetase
— Both
C4B63_49g166 ⚠
alanyl-tRNA synthetase
— Both
C4B63_6g521 ⚠
DIS3-like exonuclease
— Both
C4B63_18g130 ⚠
glutamyl-tRNA synthetase
— Both
C4B63_21g251
conserved hypothetical protein
— Both
C4B63_109g37 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
C4B63_52g161 ⚠
tyrosyl-tRNA synthetase
— Both
C4B63_82g71 ⚠
tryptophanyl-tRNA synthetase
— OG6
C4B63_10g517 ⚠
tryptophanyl-tRNA synthetase
— OG6
C4B63_34g118 ⚠
conserved hypothetical protein
— Both
C4B63_56g84 ⚠
conserved hypothetical protein
— Both
C4B63_56g85 ⚠
conserved hypothetical protein
— Both
C4B63_175g9 ⚠
heat shock protein DNAJ
— OG6
C4B63_58g135 ⚠
heat shock protein DNAJ
— OG6
C4B63_184g39 ⚠
heat shock protein DNAJ(fragment)
— OG6
C4B63_14g97 ⚠
isoleucyl-tRNA synthetase
— Both
C4B63_14g96 ⚠
isoleucil-tRNA synthetase
— Both
C4B63_40g52
conserved hypothetical protein
— Both
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_23g248 ⚠
inorganic pyrophosphatase
— Both
C4B63_70g77 ⚠
acidocalcisomal pyrophosphatase
— Both
C4B63_149g26
GDP-mannose pyrophosphorylase
— Both
C4B63_42g42
co-chaperone GrpE
— Both
C4B63_61g23 ⚠
tRNA-dihydrouridine synthase 3
— Both
C4B63_339g3 ⚠
tRNA-dihydrouridine synthase 3
— Both
C4B63_30g129 ⚠
rrp44p homologue
— OG7
C4B63_193g9 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_294g17 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_13g118 ⚠
tRNA-dihydrouridine synthase 2
— OG7
C4B63_20g51 ⚠
tRNA-dihydrouridine synthase 4
— OG7
C4B63_336g10 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_313g3 ⚠
dihydrouridine synthase (Dus)(fragment)
— OG7
C4B63_350g11 ⚠
dihydrouridine synthase (Dus)
— OG7
C4B63_25g216 ⚠
conserved hypothetical protein
— OG7
C4B63_4g245 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
C4B63_25g215 ⚠
tRNA (cytosine(34)-C(5))-methyltransferase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.