C4B63_18g239

aldehyde dehydrogenase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_108000 OG7: OG7_0000714 21 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 21 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_8g221 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_28g60 ⚠
fumarate hydratase
— Both
C4B63_23g130 ⚠
Fumarate hydratase class I, cytosolic
— Both
C4B63_41g203 ⚠
alanine aminotransferase
— Both
C4B63_41g205 ⚠
alanine aminotransferase
— Both
C4B63_23g105 ⚠
C-8 sterol isomerase
— Both
C4B63_20g208 ⚠
conserved hypothetical protein
— Both
C4B63_18g232 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— OG6
C4B63_150g38 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_57g67 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_26g353 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_46g82 ⚠
adenylosuccinate synthetase
— Both
C4B63_50g7 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_81g63 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_8g249 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_18g233 ⚠
glyceraldehyde 3-phosphate dehydrogenase
— OG6
C4B63_37g364 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
C4B63_18g164 ⚠
S-adenosylmethionine synthetase
— Both
C4B63_2g784 ⚠
glycerol kinase, glycosomal
— Both
C4B63_2g299 ⚠
conserved hypothetical protein
— Both
C4B63_170g28 ⚠
adenylosuccinate synthetase
— Both
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.