CFAC1_150007000

GDP-mannose pyrophosphorylase
Crithidia fasciculata strain Cf-Cl OG6: OG6_100460 OG7: OG7_0001668 188 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 188 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
CFAC1_180020900
glutamine synthetase, putative
— Both
CFAC1_130007400 ⚠
acidocalcisomal pyrophosphatase
— Both
CFAC1_070006300 ⚠
inorganic pyrophosphatase, putative
— Both
CFAC1_110018200 ⚠
inositol-3-phosphate synthase
— Both
CFAC1_110027100 ⚠
inositol-3-phosphate synthase
— Both
CFAC1_280011900 ⚠
heat shock protein 83
— +2 more Both
CFAC1_300056700 ⚠
Serine hydrolase (FSH1)/RWD domain/50S riboso
— OG7
CFAC1_210035800 ⚠
GTP binding protein, putative
— OG7
CFAC1_250008200 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
CFAC1_070007600 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
CFAC1_080017200 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
CFAC1_300050100 ⚠
Methyltransferase TYW3, putative
— OG7
CFAC1_290063800 ⚠
cleavage and polyadenylation specificity fact
— OG7
CFAC1_300009300 ⚠
rrp44p homologue, putative
— OG7
CFAC1_230031000 ⚠
aminopeptidase, putative
— OG7
CFAC1_230031100 ⚠
aminopeptidase, putative
— OG7
CFAC1_270051900
hypothetical protein, conserved
— Both
CFAC1_250050600
tubulin folding cofactor D, putative
— Both
CFAC1_260024100
hypothetical protein, conserved
— Both
CFAC1_280047500
paraflagellar rod component, putative
— OG6
CFAC1_240032600
vacuolar ATP synthase subunit d, putative
— Both
CFAC1_230009300
Leucine Rich repeats (2 copies), putative
— Both
CFAC1_160020400 ⚠
hypothetical protein, conserved
— Both
CFAC1_040020800 ⚠
hypothetical protein, conserved
— Both
CFAC1_300047800
Gar1/Naf1 RNA binding region containing prote
— Both
CFAC1_200008000 ⚠
ubiquitin-activating enzyme-like protein
— Both
CFAC1_280012000 ⚠
heat shock protein 83
— +2 more Both
CFAC1_130027700
ATP synthase F1 subunit gamma protein, putati
— Both
CFAC1_280071900 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
CFAC1_150014700 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
CFAC1_300039800 ⚠
serine hydroxymethyltranferase (SHMT-S)
— Both
CFAC1_280033600
hypothetical protein, conserved
— Both
CFAC1_090009400 ⚠
Dihydrouridine synthase (Dus), putative
— Both
CFAC1_110012600 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
CFAC1_230008100
Pleckstrin homology domain, putative
— Both
CFAC1_170030800
tRNA (Uracil-5-)-methyltransferase, putative
— Both
CFAC1_020007900
dihydrolipoamide branched chain transacylase,
— Both
CFAC1_110027400 ⚠
tyrosyl-tRNA synthetase, putative
— Both
CFAC1_250008000
PUB domain containing protein, putative
— Both
CFAC1_110025900 ⚠
serine hydroxymethyltranferase (SHMT-S)
— Both
CFAC1_300082100 ⚠
protein kinase, putative
— OG7
CFAC1_290048100
Zeta toxin, putative
— Both
CFAC1_100018800 ⚠
heat shock protein 90, putative
— +2 more Both
CFAC1_130012000
methionyl-tRNA synthetase
— Both
CFAC1_200009900
WD domain, G-beta repeat, putative
— Both
CFAC1_040008800
Exonuclease, putative
— Both
CFAC1_100026700
transcription factor-like protein
— Both
CFAC1_100026300 ⚠
tryptophanyl-tRNA synthetase, putative
— Both
CFAC1_200013100 ⚠
mitochondrial DNA polymerase beta
— Both
CFAC1_150010500
pteridine reductase 1
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.