CFAC1_130012000

methionyl-tRNA synthetase

Crithidia fasciculata strain Cf-Cl OG6: OG6_101119 OG7: OG7_0003306 135 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 135 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
CFAC1_260024900 histidyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003126 ↔ TCSYLVIO_007991 OG6 Tb927.10.1500 ↔ Tb927.6.2060 OG7 TCSYLVIO_003126 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.6.2060	Both
CFAC1_110027400 ⚠ tyrosyl-tRNA synthetase, putative	—	OG6 Tb927.10.1500 ↔ Tb927.7.3620 OG6 TCSYLVIO_007991 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.7.3620 +2 more	Both
CFAC1_240011400 ⚠ Putative tRNA binding domain containing prote	—	OG6 Tb927.10.1500 ↔ Tb927.7.2400 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.7.3620 +2 more	Both
CFAC1_120020900 ⚠ tyrosyl or methionyl-tRNA synthetase-like pro	—	OG6 Tb927.10.1500 ↔ Tb927.7.2400 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.7.3620 +2 more	Both
CFAC1_260056300 valyl-tRNA synthetase, putative	—	OG6 Tb927.10.1500 ↔ Tb927.6.4480 OG6 TCSYLVIO_003345 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.6.4480 OG7 TCSYLVIO_003345 ↔ TCSYLVIO_007991	Both
CFAC1_220039800 leucyl-tRNA synthetase, putative	—	OG6 Tb927.10.1500 ↔ Tb927.11.3730 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.11.3730 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007991	Both
CFAC1_240029700 hypothetical protein, conserved	—	OG6 TCSYLVIO_005083 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_005083 ↔ TCSYLVIO_007991	Both
CFAC1_250041400 ⚠ translation initiation factor IF-2, putative	—	OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007991	OG7
CFAC1_280020900 hypothetical protein, conserved	—	OG6 TCSYLVIO_004910 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004910 ↔ TCSYLVIO_007991	Both
CFAC1_230031100 ⚠ aminopeptidase, putative	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_007991	Both
CFAC1_230031000 ⚠ aminopeptidase, putative	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_007991	Both
CFAC1_180019300 Pre-mRNA-splicing factor 38, putative	—	OG6 TCSYLVIO_007337 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_007337 ↔ TCSYLVIO_007991	Both
CFAC1_260058100 UV excision repair RAD23-like protein	—	OG6 TCSYLVIO_003361 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_007991	Both
CFAC1_160026600 WD domain, G-beta repeat, putative	—	OG6 TCSYLVIO_005180 ↔ TCSYLVIO_007991	OG6
CFAC1_140005900 ⚠ kinetoplast polyadenylation/uridylation facto	—	OG6 TCSYLVIO_000834 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_007991	Both
CFAC1_230011400 hypothetical protein, conserved	—	OG6 TCSYLVIO_006404 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_006404 ↔ TCSYLVIO_007991	Both
CFAC1_140006800 ⚠ alpha glucosidase II subunit, putative	—	OG6 TCSYLVIO_006140 ↔ TCSYLVIO_007991 OG6 TCSYLVIO_006141 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_006140 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_006141 ↔ TCSYLVIO_007991	Both
CFAC1_300065900 ⚠ alpha glucosidase II subunit, putative	—	OG6 TCSYLVIO_006140 ↔ TCSYLVIO_007991 OG6 TCSYLVIO_006141 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_006140 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_006141 ↔ TCSYLVIO_007991	Both
CFAC1_240029900 hypothetical protein, conserved	—	OG6 TCSYLVIO_005084 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_005084 ↔ TCSYLVIO_007991	Both
CFAC1_240019900 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007991	Both
CFAC1_200028800 UDP-glucose:Glycoprotein Glucosyltransferase,	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_007991	Both
CFAC1_250032800 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007991	Both
CFAC1_200033300 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007991	Both
CFAC1_250007300 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007991	OG6
CFAC1_210029800 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007991	OG6
CFAC1_220008900 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_005414 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007991	Both
CFAC1_240023800 alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007991	Both
CFAC1_280063200 isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007991	Both
CFAC1_260023100 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007991	Both
CFAC1_130014800 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007991	Both
CFAC1_300010400 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007991 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007991	Both
CFAC1_150007000 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_007991	Both
CFAC1_260026300 ⚠ co-chaperone GrpE, putative	—	OG6 TCSYLVIO_003139 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003139 ↔ TCSYLVIO_007991	Both
CFAC1_300047800 Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007991	Both
CFAC1_130007400 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007991	Both
CFAC1_070006300 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007991	Both
CFAC1_070011900 ⚠ aminopeptidase, putative	—	OG7 TCSYLVIO_005560 ↔ TCSYLVIO_007991	OG7
CFAC1_300009300 ⚠ rrp44p homologue, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007991	OG7
CFAC1_070012000 ⚠ aminopeptidase, putative	—	OG7 TCSYLVIO_005560 ↔ TCSYLVIO_007991	OG7
CFAC1_260006100 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_006877 ↔ TCSYLVIO_007991	OG7
CFAC1_300079500 ⚠ pentatricopeptide repeat domain containing pr	—	OG7 TCSYLVIO_000834 ↔ TCSYLVIO_007991	OG7
CFAC1_280011900 ⚠ heat shock protein 83	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_007991	OG7
CFAC1_280012000 ⚠ heat shock protein 83	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_007991	OG7
CFAC1_100018800 ⚠ heat shock protein 90, putative	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_007991	OG7
CFAC1_090019600 ⚠ NOL1/NOP2/sun family, putative	—	OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007991	OG7
CFAC1_140020500 ⚠ Multisite-specific tRNA:(cytosine-C(5))-methy	—	OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007991	OG7
CFAC1_260006200 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_006877 ↔ TCSYLVIO_007991	OG7
CFAC1_260026400 ⚠ heat shock protein grpe	—	OG7 TCSYLVIO_003139 ↔ TCSYLVIO_007991	OG7
CFAC1_260025800 ⚠ nuclear movement protein, putative	—	OG7 TCSYLVIO_007991 ↔ TCSYLVIO_010327	OG7
CFAC1_250011700 ⚠ dihydrouridine synthase domain protein-like p	—	OG7 TCSYLVIO_007991 ↔ TCSYLVIO_009102	OG7

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