CFAC1_280063200

isoleucyl-tRNA synthetase, putative

Crithidia fasciculata strain Cf-Cl OG6: OG6_100811 OG7: OG7_0003029 203 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 203 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
CFAC1_170031400 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1	OG6
CFAC1_110027400 ⚠ tyrosyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010624 OG7 Tb927.10.9190 ↔ Tb927.8.5330	Both
CFAC1_010015200 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1	OG6
CFAC1_170031200 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1	OG6
CFAC1_240011400 ⚠ Putative tRNA binding domain containing prote	—	OG6 Tb927.10.9190 ↔ Tb927.8.5330 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010624 +1 more	Both
CFAC1_120020900 ⚠ tyrosyl or methionyl-tRNA synthetase-like pro	—	OG6 Tb927.10.9190 ↔ Tb927.8.5330 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010624 +1 more	Both
CFAC1_290052300 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 Tb927.10.9190 ↔ Tb927.4.2310 OG6 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 +1 more	Both
CFAC1_220039800 leucyl-tRNA synthetase, putative	—	OG6 Tb927.10.9190 ↔ Tb927.11.3730 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.11.3730 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004705	Both
CFAC1_010015000 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1	OG6
CFAC1_010015400 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1	OG6
CFAC1_260034200 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1	OG6
CFAC1_070011900 ⚠ aminopeptidase, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
CFAC1_070012000 ⚠ aminopeptidase, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
CFAC1_290014800 ⚠ amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1	OG6
CFAC1_170031300 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1	OG6
CFAC1_010015100 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1	OG6
CFAC1_010015300 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1	OG6
CFAC1_230031000 ⚠ aminopeptidase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005560 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
CFAC1_230031100 ⚠ aminopeptidase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005560 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
CFAC1_130014800 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.4.2310	Both
CFAC1_260023100 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.4.2310	Both
CFAC1_220008900 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005414 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005414	Both
CFAC1_190020400 ⚠ small nuclear ribonucleoprotein, putative	—	OG7 LdBPK_354530.1 ↔ LdBPK_365870.1 OG7 LdBPK_301270.1 ↔ LdBPK_365870.1	OG7
CFAC1_230016000 ⚠ LSM domain containing protein, putative	—	OG7 LdBPK_354530.1 ↔ LdBPK_365870.1 OG7 LdBPK_301270.1 ↔ LdBPK_365870.1	OG7
CFAC1_050006700 ⚠ LSM domain containing protein, putative	—	OG7 LdBPK_354530.1 ↔ LdBPK_365870.1 OG7 LdBPK_301270.1 ↔ LdBPK_365870.1	OG7
CFAC1_260041100 ⚠ 3-oxoacid CoA-transferase, A subunit, putativ	—	OG7 LdBPK_301910.1 ↔ LdBPK_365870.1	OG7
CFAC1_190034100 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_070810.1 ↔ LdBPK_365870.1	OG7
CFAC1_300009300 ⚠ rrp44p homologue, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004705	OG7
CFAC1_010008700 ⚠ ornithine decarboxylase, putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_365870.1 OG7 LdBPK_120105.1 ↔ LdBPK_365870.1	Both
CFAC1_160015600 ⚠ diaminopimelate decarboxylase, putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_365870.1	OG6
CFAC1_220011400 Translation initiation factor SUI1, putative	—	OG6 LdBPK_250420.1 ↔ LdBPK_365870.1 OG7 LdBPK_250420.1 ↔ LdBPK_365870.1	Both
CFAC1_070006300 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004705	Both
CFAC1_130007400 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004705	Both
CFAC1_300047800 Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_004705	Both
CFAC1_260026300 ⚠ co-chaperone GrpE, putative	—	OG6 TCSYLVIO_003139 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003139 ↔ TCSYLVIO_004705	Both
CFAC1_100020600 ⚠ NF-X1 type zinc finger containing protein, pu	—	OG6 LdBPK_290620.1 ↔ LdBPK_365870.1 OG7 LdBPK_290620.1 ↔ LdBPK_365870.1	Both
CFAC1_300010400 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004705	Both
CFAC1_170008700 ⚠ polyprenyl synthase, putative	—	OG6 LdBPK_190210.1 ↔ LdBPK_365870.1 OG7 LdBPK_190210.1 ↔ LdBPK_365870.1	Both
CFAC1_170016800 ⚠ ABC transport system ATP-binding protein, put	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006012 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006012	Both
CFAC1_300065900 ⚠ alpha glucosidase II subunit, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006141	Both
CFAC1_280057800 VHS domain containing protein, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008292 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008292	Both
CFAC1_110025900 ⚠ serine hydroxymethyltranferase (SHMT-S)	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010621	Both
CFAC1_130012000 methionyl-tRNA synthetase	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007991	Both
CFAC1_260012000 la RNA binding protein, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006827 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006827	Both
CFAC1_280045100 hypothetical protein, conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008197 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008197	Both
CFAC1_300076500 acyl-CoA dehydrogenase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005872 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005872	Both
CFAC1_200033300 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_004998 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_004998	Both
CFAC1_280020900 hypothetical protein, conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_004910 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_004910	Both
CFAC1_230037000 arginyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005509 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005509	Both
CFAC1_220017400 protein kinase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007401 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007401	Both

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