CFAC1_210011400

fumarate hydratase, putative

Crithidia fasciculata strain Cf-Cl OG6: OG6_102839 OG7: OG7_0008166 44 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 44 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
CFAC1_260060800 ⚠ S-adenosylmethionine synthetase	—	OG6 Tb927.3.4500 ↔ Tb927.6.4840 OG7 Tb927.3.4500 ↔ Tb927.6.4840	Both
CFAC1_010013400 ⚠ alanine aminotransferase	—	OG6 Tb927.1.3950 ↔ Tb927.11.5050 OG6 Tb927.1.3950 ↔ Tb927.3.4500 OG7 Tb927.1.3950 ↔ Tb927.11.5050 OG7 Tb927.1.3950 ↔ Tb927.3.4500	Both
CFAC1_200029100 ⚠ C-8 sterol isomerase-like protein	—	OG6 Tb927.3.4500 ↔ Tb927.3.4650 OG7 Tb927.3.4500 ↔ Tb927.3.4650	Both
CFAC1_140027800 ⚠ Inosine-uridine preferring nucleoside hydrola	—	OG6 Tb927.3.4500 ↔ Tb927.7.4570 OG7 Tb927.3.4500 ↔ Tb927.7.4570	Both
CFAC1_140027700 ⚠ nonspecific nucleoside hydrolase	—	OG6 Tb927.3.4500 ↔ Tb927.7.4570 OG7 Tb927.3.4500 ↔ Tb927.7.4570	Both
CFAC1_240042700 ⚠ glutamate dehydrogenase	—	OG6 Tb927.3.4500 ↔ Tb927.9.5900 OG7 Tb927.3.4500 ↔ Tb927.9.5900	Both
CFAC1_020015900 ⚠ methylthioadenosine phosphorylase, putative	—	OG6 Tb927.3.4500 ↔ Tb927.7.7040 OG6 Tb927.11.5050 ↔ Tb927.7.7040 OG7 Tb927.3.4500 ↔ Tb927.7.7040 OG7 Tb927.11.5050 ↔ Tb927.7.7040	Both
CFAC1_250051200 ⚠ transketolase	—	OG6 Tb927.3.4500 ↔ Tb927.8.6170 OG7 Tb927.3.4500 ↔ Tb927.8.6170	Both
CFAC1_300081100 ⚠ glycerol kinase, glycosomal, putative	—	OG6 Tb927.3.4500 ↔ Tb927.9.12570 OG6 Tb927.11.5050 ↔ Tb927.9.12570 OG7 Tb927.3.4500 ↔ Tb927.9.12570 OG7 Tb927.11.5050 ↔ Tb927.9.12570	Both
CFAC1_260060700 ⚠ S-adenosylmethionine synthetase	—	OG6 Tb927.3.4500 ↔ Tb927.6.4840 OG7 Tb927.3.4500 ↔ Tb927.6.4840	Both
CFAC1_250051100 ⚠ transketolase	—	OG6 Tb927.3.4500 ↔ Tb927.8.6170 OG7 Tb927.3.4500 ↔ Tb927.8.6170	Both
CFAC1_010013300 ⚠ alanine aminotransferase	—	OG6 Tb927.1.3950 ↔ Tb927.11.5050 OG6 Tb927.1.3950 ↔ Tb927.3.4500 OG7 Tb927.1.3950 ↔ Tb927.11.5050 OG7 Tb927.1.3950 ↔ Tb927.3.4500	Both
CFAC1_300083800 ⚠ 6-phosphogluconate dehydrogenase, decarboxyla	—	OG6 Tb927.11.5050 ↔ Tb927.9.12110 OG7 Tb927.11.5050 ↔ Tb927.9.12110	Both
CFAC1_250051700 ⚠ 3-hydroxy-3-methylglutaryl-CoA synthase, puta	—	OG6 Tb927.3.4500 ↔ Tb927.8.6110 OG6 Tb927.11.5050 ↔ Tb927.8.6110 OG7 Tb927.3.4500 ↔ Tb927.8.6110 OG7 Tb927.11.5050 ↔ Tb927.8.6110	Both
CFAC1_260053600 ⚠ aldehyde dehydrogenase, putative	—	OG6 Tb927.3.4500 ↔ Tb927.6.4210 OG7 Tb927.3.4500 ↔ Tb927.6.4210	Both
CFAC1_030012800 ⚠ adenylosuccinate lyase, putative	—	OG6 Tb927.11.5050 ↔ Tb927.9.7550 OG7 Tb927.11.5050 ↔ Tb927.9.7550	Both
CFAC1_100017500 ⚠ guanine deaminase, putative	—	OG6 Tb927.3.4500 ↔ Tb927.5.4560 OG7 Tb927.3.4500 ↔ Tb927.5.4560	Both
CFAC1_110006500 ⚠ inosine-guanine nucleoside hydrolase, putativ	—	OG6 Tb927.3.4500 ↔ Tb927.7.4570 OG7 Tb927.3.4500 ↔ Tb927.7.4570	Both
CFAC1_200027300 ⚠ fumarate hydratase, putative	—	OG6 Tb927.11.5050 ↔ Tb927.3.4500 OG7 Tb927.11.5050 ↔ Tb927.3.4500	Both
CFAC1_190043400 ⚠ nucleoside diphosphate kinase b	—	OG6 Tb927.11.16130 ↔ Tb927.11.5050 OG6 Tb927.11.16130 ↔ Tb927.3.4500 OG7 Tb927.11.16130 ↔ Tb927.11.5050 OG7 Tb927.11.16130 ↔ Tb927.3.4500	Both
CFAC1_190043300 ⚠ nucleoside diphosphate kinase b	—	OG6 Tb927.11.16130 ↔ Tb927.11.5050 OG6 Tb927.11.16130 ↔ Tb927.3.4500 OG7 Tb927.11.16130 ↔ Tb927.11.5050 OG7 Tb927.11.16130 ↔ Tb927.3.4500	Both
CFAC1_280058200 ⚠ aldehyde dehydrogenase, putative	—	OG7 Tb927.3.4500 ↔ Tb927.6.4210	OG7
CFAC1_250034900 ⚠ glyceraldehyde 3-phosphate dehydrogenase, cyt	—	OG6 Tb927.10.6880 ↔ Tb927.3.4500 OG7 Tb927.10.6880 ↔ Tb927.3.4500 OG7 Tb927.3.4500 ↔ Tb927.9.9820	Both
CFAC1_210016800 ⚠ malic enzyme, putative	—	OG6 Tb927.11.5440 ↔ Tb927.3.4500 OG6 Tb927.11.5050 ↔ Tb927.11.5440 OG7 Tb927.11.5440 ↔ Tb927.3.4500 OG7 Tb927.11.5050 ↔ Tb927.11.5440	Both
CFAC1_210016900 ⚠ malic enzyme, putative	—	OG6 Tb927.11.5440 ↔ Tb927.3.4500 OG6 Tb927.11.5050 ↔ Tb927.11.5440 OG7 Tb927.11.5440 ↔ Tb927.3.4500 OG7 Tb927.11.5050 ↔ Tb927.11.5440	Both
CFAC1_140015100 ⚠ citrate synthase, putative	—	OG6 Tb927.10.13430 ↔ Tb927.11.5050 OG7 Tb927.10.13430 ↔ Tb927.11.5050	Both
CFAC1_300082700 ⚠ cystathione gamma lyase, putative	—	OG6 TCSYLVIO_004350 ↔ TCSYLVIO_005821 OG7 TCSYLVIO_004350 ↔ TCSYLVIO_005821	Both
CFAC1_110012700 ⚠ cystathionine beta-lyase-like protein	—	OG6 TCSYLVIO_004350 ↔ TCSYLVIO_005821 OG7 TCSYLVIO_004350 ↔ TCSYLVIO_005821	Both
CFAC1_300057500 ⚠ protein phosphatase 2A catalytic subunit, put	—	OG6 TCSYLVIO_004350 ↔ TCSYLVIO_005289	OG6
CFAC1_250027900 ⚠ aldehyde dehydrogenase, putative	—	OG6 TCSYLVIO_004350 ↔ TCSYLVIO_004949 OG7 TCSYLVIO_004350 ↔ TCSYLVIO_004949	Both
CFAC1_300043700 ⚠ protein phosphatase 4 catalytic subunit, puta	—	OG6 TCSYLVIO_004350 ↔ TCSYLVIO_005289	OG6
CFAC1_260054400 ⚠ glyceraldehyde 3-phosphate dehydrogenase, gly	—	OG6 Tb927.10.6880 ↔ Tb927.3.4500 OG7 Tb927.10.6880 ↔ Tb927.3.4500 OG7 Tb927.3.4500 ↔ Tb927.9.9820	Both
CFAC1_260054300 ⚠ glyceraldehyde 3-phosphate dehydrogenase, gly	—	OG6 Tb927.10.6880 ↔ Tb927.3.4500 OG7 Tb927.10.6880 ↔ Tb927.3.4500 OG7 Tb927.3.4500 ↔ Tb927.9.9820	Both
CFAC1_220040800 ⚠ adenylosuccinate synthetase, putative	—	OG6 Tb927.11.3650 ↔ Tb927.3.4500 OG7 Tb927.11.3650 ↔ Tb927.3.4500	Both
CFAC1_110022700 ⚠ enolase	—	OG6 Tb927.10.2890 ↔ Tb927.11.5050 OG6 Tb927.10.2890 ↔ Tb927.3.4500 OG7 Tb927.10.2890 ↔ Tb927.11.5050 OG7 Tb927.10.2890 ↔ Tb927.3.4500	Both
CFAC1_110022600 ⚠ enolase	—	OG6 Tb927.10.2890 ↔ Tb927.11.5050 OG6 Tb927.10.2890 ↔ Tb927.3.4500 OG7 Tb927.10.2890 ↔ Tb927.11.5050 OG7 Tb927.10.2890 ↔ Tb927.3.4500	Both
CFAC1_110024200 ⚠ enolase	—	OG6 Tb927.10.2890 ↔ Tb927.11.5050 OG6 Tb927.10.2890 ↔ Tb927.3.4500 OG7 Tb927.10.2890 ↔ Tb927.11.5050 OG7 Tb927.10.2890 ↔ Tb927.3.4500	Both
CFAC1_110023600 ⚠ enolase	—	OG6 Tb927.10.2890 ↔ Tb927.11.5050 OG6 Tb927.10.2890 ↔ Tb927.3.4500 OG7 Tb927.10.2890 ↔ Tb927.11.5050 OG7 Tb927.10.2890 ↔ Tb927.3.4500	Both
CFAC1_110024100 ⚠ enolase	—	OG6 Tb927.10.2890 ↔ Tb927.11.5050 OG6 Tb927.10.2890 ↔ Tb927.3.4500 OG7 Tb927.10.2890 ↔ Tb927.11.5050 OG7 Tb927.10.2890 ↔ Tb927.3.4500	Both
CFAC1_110024000 ⚠ enolase	—	OG6 Tb927.10.2890 ↔ Tb927.11.5050 OG6 Tb927.10.2890 ↔ Tb927.3.4500 OG7 Tb927.10.2890 ↔ Tb927.11.5050 OG7 Tb927.10.2890 ↔ Tb927.3.4500	Both
CFAC1_110023900 ⚠ enolase	—	OG6 Tb927.10.2890 ↔ Tb927.11.5050 OG6 Tb927.10.2890 ↔ Tb927.3.4500 OG7 Tb927.10.2890 ↔ Tb927.11.5050 OG7 Tb927.10.2890 ↔ Tb927.3.4500	Both
CFAC1_020010000 ⚠ trypanothione reductase	—	OG6 Tb927.10.10390 ↔ Tb927.3.4500 OG7 Tb927.10.10390 ↔ Tb927.3.4500	Both
CFAC1_140013000 ⚠ aconitase, putative	—	OG6 Tb927.10.14000 ↔ Tb927.11.5050 OG6 Tb927.10.14000 ↔ Tb927.3.4500 OG7 Tb927.10.14000 ↔ Tb927.11.5050 OG7 Tb927.10.14000 ↔ Tb927.3.4500	Both
CFAC1_010013500 ⚠ alanine aminotransferase	—	OG6 Tb927.1.3950 ↔ Tb927.11.5050 OG6 Tb927.1.3950 ↔ Tb927.3.4500 OG7 Tb927.1.3950 ↔ Tb927.11.5050 OG7 Tb927.1.3950 ↔ Tb927.3.4500	Both