CFAC1_210016800

malic enzyme, putative

Crithidia fasciculata strain Cf-Cl OG6: OG6_100205 OG7: OG7_0002857 61 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 61 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
CFAC1_290016600 ⚠ heat shock 70 protein-like protein	—	OG7 TCSYLVIO_001501 ↔ TCSYLVIO_002194	OG7
CFAC1_100017500 ⚠ guanine deaminase, putative	—	OG6 TCSYLVIO_001501 ↔ TCSYLVIO_007737 OG7 TCSYLVIO_001501 ↔ TCSYLVIO_007737	Both
CFAC1_280039500 ⚠ cysteine synthase	—	OG6 TCSYLVIO_001501 ↔ TCSYLVIO_008128 OG7 TCSYLVIO_001501 ↔ TCSYLVIO_008128	Both
CFAC1_050016800 ⚠ Uncharacterised protein family (UPF0160), put	—	OG6 TCSYLVIO_001501 ↔ TCSYLVIO_006555 OG7 TCSYLVIO_001501 ↔ TCSYLVIO_006555	Both
CFAC1_300045200 ⚠ heat shock 70-related protein 1, mitochondria	—	OG6 TCSYLVIO_001501 ↔ TCSYLVIO_002194	OG6
CFAC1_010013500 ⚠ alanine aminotransferase	—	OG6 Tb927.1.3950 ↔ Tb927.11.5450 OG6 Tb927.1.3950 ↔ Tb927.11.5440 OG7 Tb927.1.3950 ↔ Tb927.11.5450 OG7 Tb927.1.3950 ↔ Tb927.11.5440	Both
CFAC1_010013300 ⚠ alanine aminotransferase	—	OG6 Tb927.1.3950 ↔ Tb927.11.5450 OG6 Tb927.1.3950 ↔ Tb927.11.5440 OG7 Tb927.1.3950 ↔ Tb927.11.5450 OG7 Tb927.1.3950 ↔ Tb927.11.5440	Both
CFAC1_010013400 ⚠ alanine aminotransferase	—	OG6 Tb927.1.3950 ↔ Tb927.11.5450 OG6 Tb927.1.3950 ↔ Tb927.11.5440 OG7 Tb927.1.3950 ↔ Tb927.11.5450 OG7 Tb927.1.3950 ↔ Tb927.11.5440	Both
CFAC1_150018300 ⚠ acetyl-CoA synthetase, putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_001501 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_001501	Both
CFAC1_150013700 ⚠ acetyl-CoA synthetase, putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_001501 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_001501	Both
CFAC1_270068200 ⚠ phosphoglycan beta 1,3 galactosyltransferase	—	OG6 LdBPK_240780.1 ↔ LdBPK_313210.1 OG7 LdBPK_240780.1 ↔ LdBPK_313210.1	Both
CFAC1_260037900 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_240780.1 ↔ LdBPK_301690.1 OG7 LdBPK_240780.1 ↔ LdBPK_301690.1	Both
CFAC1_210035400 ⚠ trypanothione synthetase, putative	—	OG6 TCSYLVIO_000427 ↔ TCSYLVIO_001501 OG7 TCSYLVIO_000427 ↔ TCSYLVIO_001501	Both
CFAC1_280076400 ⚠ 2,3-bisphosphoglycerate-independent phosphogl	—	OG6 Tb927.10.7930 ↔ Tb927.11.5450 OG7 Tb927.10.7930 ↔ Tb927.11.5450	Both
CFAC1_050012600 ⚠ HSP70-like protein	—	OG7 TCSYLVIO_001501 ↔ TCSYLVIO_002194	OG7
CFAC1_140023200 ⚠ heat shock protein 110, putative	—	OG7 TCSYLVIO_001501 ↔ TCSYLVIO_002194	OG7
CFAC1_300021300 ⚠ heat shock 70-related protein 1, mitochondria	—	OG6 TCSYLVIO_001501 ↔ TCSYLVIO_002194 OG7 TCSYLVIO_001501 ↔ TCSYLVIO_002194	Both
CFAC1_070011900 ⚠ aminopeptidase, putative	—	OG7 TCSYLVIO_001500 ↔ TCSYLVIO_005560	OG7
CFAC1_300098600 ⚠ Hsp70 protein, putative	—	OG7 TCSYLVIO_001501 ↔ TCSYLVIO_002194	OG7
CFAC1_070012000 ⚠ aminopeptidase, putative	—	OG7 TCSYLVIO_001500 ↔ TCSYLVIO_005560	OG7
CFAC1_210040100 ⚠ D-alanyl-glycyl endopeptidase-like protein	—	OG7 TCSYLVIO_000427 ↔ TCSYLVIO_001501	OG7
CFAC1_230008300 ⚠ glutathionylspermidine synthase, putative	—	OG7 TCSYLVIO_000427 ↔ TCSYLVIO_001501	OG7
CFAC1_210039300 ⚠ D-alanyl-glycyl endopeptidase-like protein	—	OG7 TCSYLVIO_000427 ↔ TCSYLVIO_001501	OG7
CFAC1_150012500 ⚠ trypanothione synthetase, putative	—	OG7 TCSYLVIO_000427 ↔ TCSYLVIO_001501	OG7
CFAC1_200024800 ⚠ paraflagellar rod protein 2C	—	OG7 TCSYLVIO_000425 ↔ TCSYLVIO_001501	OG7
CFAC1_120025400 ⚠ paraflagellar rod protein 2C	—	OG7 TCSYLVIO_000425 ↔ TCSYLVIO_001501	OG7
CFAC1_280062500 ⚠ aminopeptidase P1, putative	—	OG7 TCSYLVIO_001380 ↔ TCSYLVIO_001501	OG7
CFAC1_230012000 ⚠ elongation factor 2-like protein	—	OG7 Tb927.10.4560 ↔ Tb927.11.5450 OG7 Tb927.10.4560 ↔ Tb927.11.5440	OG7
CFAC1_190035000 ⚠ small nuclear ribonucleoprotein component-lik	—	OG7 Tb927.10.4560 ↔ Tb927.11.5450 OG7 Tb927.10.4560 ↔ Tb927.11.5440	OG7
CFAC1_060007300 ⚠ ATP-binding cassette protein subfamily F, mem	—	OG7 LdBPK_240780.1 ↔ LdBPK_330340.1	OG7
CFAC1_170016800 ⚠ ABC transport system ATP-binding protein, put	—	OG7 LdBPK_240780.1 ↔ LdBPK_330340.1	OG7
CFAC1_110023900 ⚠ enolase	—	OG6 Tb927.10.2890 ↔ Tb927.11.5450 OG6 Tb927.10.2890 ↔ Tb927.11.5440 OG7 Tb927.10.2890 ↔ Tb927.11.5450 OG7 Tb927.10.2890 ↔ Tb927.11.5440	Both
CFAC1_140015100 ⚠ citrate synthase, putative	—	OG6 Tb927.10.13430 ↔ Tb927.11.5450 OG6 Tb927.10.13430 ↔ Tb927.11.5440 OG7 Tb927.10.13430 ↔ Tb927.11.5450 OG7 Tb927.10.13430 ↔ Tb927.11.5440	Both
CFAC1_210016900 ⚠ malic enzyme, putative	—	OG6 Tb927.11.5440 ↔ Tb927.11.5450 OG7 Tb927.11.5440 ↔ Tb927.11.5450	Both
CFAC1_300083800 ⚠ 6-phosphogluconate dehydrogenase, decarboxyla	—	OG6 Tb927.11.5440 ↔ Tb927.9.12110 OG6 Tb927.11.5450 ↔ Tb927.9.12110 OG7 Tb927.11.5440 ↔ Tb927.9.12110 OG7 Tb927.11.5450 ↔ Tb927.9.12110	Both
CFAC1_210011400 ⚠ fumarate hydratase, putative	—	OG6 Tb927.11.5440 ↔ Tb927.3.4500 OG6 Tb927.11.5050 ↔ Tb927.11.5440 OG7 Tb927.11.5440 ↔ Tb927.3.4500 OG7 Tb927.11.5050 ↔ Tb927.11.5440	Both
CFAC1_230011200 ⚠ succinyl-CoA synthetase alpha subunit, putati	—	OG6 Tb927.11.5450 ↔ Tb927.3.2230 OG7 Tb927.11.5450 ↔ Tb927.3.2230	Both
CFAC1_200027300 ⚠ fumarate hydratase, putative	—	OG6 Tb927.11.5440 ↔ Tb927.3.4500 OG6 Tb927.11.5050 ↔ Tb927.11.5440 OG7 Tb927.11.5440 ↔ Tb927.3.4500 OG7 Tb927.11.5050 ↔ Tb927.11.5440	Both
CFAC1_230011300 ⚠ succinyl-CoA synthetase alpha subunit, putati	—	OG6 Tb927.11.5450 ↔ Tb927.3.2230 OG7 Tb927.11.5450 ↔ Tb927.3.2230	Both
CFAC1_030019800 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_041000.1 ↔ LdBPK_240780.1 OG7 LdBPK_041000.1 ↔ LdBPK_240780.1	Both
CFAC1_110022700 ⚠ enolase	—	OG6 Tb927.10.2890 ↔ Tb927.11.5450 OG6 Tb927.10.2890 ↔ Tb927.11.5440 OG7 Tb927.10.2890 ↔ Tb927.11.5450 OG7 Tb927.10.2890 ↔ Tb927.11.5440	Both
CFAC1_110022600 ⚠ enolase	—	OG6 Tb927.10.2890 ↔ Tb927.11.5450 OG6 Tb927.10.2890 ↔ Tb927.11.5440 OG7 Tb927.10.2890 ↔ Tb927.11.5450 OG7 Tb927.10.2890 ↔ Tb927.11.5440	Both
CFAC1_110024200 ⚠ enolase	—	OG6 Tb927.10.2890 ↔ Tb927.11.5450 OG6 Tb927.10.2890 ↔ Tb927.11.5440 OG7 Tb927.10.2890 ↔ Tb927.11.5450 OG7 Tb927.10.2890 ↔ Tb927.11.5440	Both
CFAC1_110023600 ⚠ enolase	—	OG6 Tb927.10.2890 ↔ Tb927.11.5450 OG6 Tb927.10.2890 ↔ Tb927.11.5440 OG7 Tb927.10.2890 ↔ Tb927.11.5450 OG7 Tb927.10.2890 ↔ Tb927.11.5440	Both
CFAC1_110024100 ⚠ enolase	—	OG6 Tb927.10.2890 ↔ Tb927.11.5450 OG6 Tb927.10.2890 ↔ Tb927.11.5440 OG7 Tb927.10.2890 ↔ Tb927.11.5450 OG7 Tb927.10.2890 ↔ Tb927.11.5440	Both
CFAC1_110024000 ⚠ enolase	—	OG6 Tb927.10.2890 ↔ Tb927.11.5450 OG6 Tb927.10.2890 ↔ Tb927.11.5440 OG7 Tb927.10.2890 ↔ Tb927.11.5450 OG7 Tb927.10.2890 ↔ Tb927.11.5440	Both
CFAC1_040009000 ⚠ isocitrate dehydrogenase [NADP], mitochondria	—	OG6 Tb927.11.5440 ↔ Tb927.8.3690 OG6 Tb927.11.5440 ↔ Tb927.11.900 OG6 Tb927.11.5450 ↔ Tb927.11.900 OG7 Tb927.11.5440 ↔ Tb927.8.3690 +2 more	Both
CFAC1_210035600 ⚠ paraflagellar rod protein-like protein	—	OG6 TCSYLVIO_000425 ↔ TCSYLVIO_001501 OG7 TCSYLVIO_000425 ↔ TCSYLVIO_001501	Both
CFAC1_300072400 ⚠ aminopeptidase P, putative	—	OG6 TCSYLVIO_001380 ↔ TCSYLVIO_001501 OG7 TCSYLVIO_001380 ↔ TCSYLVIO_001501	Both
CFAC1_250008600 ⚠ elongation factor 2	—	OG6 Tb927.10.4560 ↔ Tb927.11.5450 OG6 Tb927.10.4560 ↔ Tb927.11.5440 OG7 Tb927.10.4560 ↔ Tb927.11.5450 OG7 Tb927.10.4560 ↔ Tb927.11.5440	Both

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