CFAC1_240024400

exosome complex exonuclease RRP45 homolog, putative

Crithidia fasciculata strain Cf-Cl OG6: OG6_100420 OG7: OG7_0002825 70 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 70 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
CFAC1_110005300 ⚠ exosome complex exonuclease, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010369 OG6 Tb927.6.670 ↔ Tb927.7.4670 OG6 Tb927.11.16600 ↔ Tb927.7.4670 OG6 LdBPK_140010.1 ↔ LdBPK_221430.1 +4 more	Both
CFAC1_290060300 ⚠ exosome subunit rrp6p homologue, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_003804 OG6 LdBPK_044330.1 ↔ LdBPK_221430.1 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_003804 OG7 LdBPK_044330.1 ↔ LdBPK_221430.1	Both
CFAC1_160013900 ⚠ ribosomal RNA processing protein, putative	—	OG6 LdBPK_020290.1 ↔ LdBPK_221430.1 OG6 Tb927.11.16600 ↔ Tb927.2.2180 OG7 Tb927.11.16600 ↔ Tb927.2.2180 OG7 Tb927.10.7450 ↔ Tb927.6.670 +2 more	Both
CFAC1_030007200 ⚠ exosome complex exonuclease RRP40, putative	—	OG6 LdBPK_040130.1 ↔ LdBPK_221430.1 OG6 Tb927.6.670 ↔ Tb927.9.7070 OG6 Tb927.11.16600 ↔ Tb927.9.7070 OG7 Tb927.6.670 ↔ Tb927.9.7070 +2 more	Both
CFAC1_280054900 ⚠ exosome-associated protein 4, putative	—	OG7 Tb927.11.16600 ↔ Tb927.2.2180 OG7 Tb927.10.7450 ↔ Tb927.6.670 OG7 Tb927.10.7450 ↔ Tb927.11.16600 OG7 LdBPK_020290.1 ↔ LdBPK_221430.1	OG7
CFAC1_280032800 ⚠ exosome complex exonuclease RRP41, putative	—	OG6 Tb927.10.7450 ↔ Tb927.6.670 OG6 Tb927.10.7450 ↔ Tb927.11.16600 OG7 Tb927.11.16600 ↔ Tb927.2.2180 OG7 Tb927.10.7450 ↔ Tb927.6.670 +2 more	Both
CFAC1_290020800 ⚠ heat shock 70-related protein 1, mitochondria	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
CFAC1_300045200 ⚠ heat shock 70-related protein 1, mitochondria	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710	OG6
CFAC1_300021300 ⚠ heat shock 70-related protein 1, mitochondria	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
CFAC1_150031200 ⚠ Csl4p homologue, putative	—	OG6 Tb927.11.16600 ↔ Tb927.5.1200 OG6 Tb927.5.1200 ↔ Tb927.6.670 OG7 Tb927.11.16600 ↔ Tb927.5.1200 OG7 Tb927.5.1200 ↔ Tb927.6.670	Both
CFAC1_300052700 ⚠ exosome-associated protein 2, putative	—	OG6 Tb927.11.16600 ↔ Tb927.6.670 OG7 Tb927.11.16600 ↔ Tb927.6.670	Both
CFAC1_300044700 ⚠ heat shock 70-related protein 1, mitochondria	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
CFAC1_300044800 ⚠ heat shock 70-related protein 1, mitochondria	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
CFAC1_050012600 ⚠ HSP70-like protein	—	OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.10.12710 ↔ Tb927.6.670	OG7
CFAC1_300006800 ⚠ proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_001893	Both
CFAC1_250024100 ⚠ translation elongation factor 1-beta, putativ	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
CFAC1_290038100 ⚠ translation elongation factor 1-beta, putativ	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
CFAC1_300071600 ⚠ ATP-dependent RNA helicase-like protein	—	OG6 TCSYLVIO_001373 ↔ TCSYLVIO_001893	OG6
CFAC1_130017500 ⚠ T-complex protein 1, delta subunit, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	Both
CFAC1_280060700 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004731	Both
CFAC1_170013400 ⚠ DNA-directed RNA polymerases I and III subuni	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010718	OG7
CFAC1_110009500 ⚠ proteasome alpha 3 subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
CFAC1_280079400 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
CFAC1_230037800 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
CFAC1_130028300 ⚠ proteasome subunit alpha type-5, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
CFAC1_200010900 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004731	OG7
CFAC1_230050900 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
CFAC1_250026200 ⚠ proteasome alpha 1 subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
CFAC1_220046300 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
CFAC1_130007900 ⚠ proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	Both
CFAC1_300089100 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
CFAC1_180005900 ⚠ DNA-directed RNA polymerase II subunit 2, put	—	OG7 Tb927.11.16600 ↔ Tb927.11.630 OG7 Tb927.11.630 ↔ Tb927.6.670	OG7
CFAC1_290010600 ⚠ Conserved hypothetical ATP binding protein, p	—	OG7 Tb927.11.16600 ↔ Tb927.3.1150 OG7 Tb927.3.1150 ↔ Tb927.6.670	OG7
CFAC1_300098600 ⚠ Hsp70 protein, putative	—	OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.10.12710 ↔ Tb927.6.670	OG7
CFAC1_270007700 ⚠ DNA-directed RNA polymerase II subunit 2, put	—	OG7 Tb927.11.16600 ↔ Tb927.11.630 OG7 Tb927.11.630 ↔ Tb927.6.670	OG7
CFAC1_290016600 ⚠ heat shock 70 protein-like protein	—	OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.10.12710 ↔ Tb927.6.670	OG7
CFAC1_250026800 ⚠ proteasome beta 5 subunit, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006999	Both
CFAC1_130008400 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_001893	Both
CFAC1_130026900 ⚠ proteasome alpha 2 subunit, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	Both
CFAC1_110022300 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010606	Both
CFAC1_290031700 ⚠ eukaryotic translation initiation factor 5, p	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
CFAC1_010005800 ⚠ proteasome beta-1 subunit, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006999	Both
CFAC1_200006700 ⚠ adaptor complex protein (AP) 3 delta subunit	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010530 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010530	Both
CFAC1_100025500 ⚠ DNA-directed RNA polymerase I-like protein	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010718 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010718	Both
CFAC1_190019700 ⚠ chaperonin containing t-complex protein, puta	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	Both
CFAC1_150026500 ⚠ T-complex protein 1, gamma subunit, putative	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	Both
CFAC1_050024200 ⚠ paraflagellar rod component, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_006797 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006797	Both
CFAC1_170027500 ⚠ RNasePH-like protein	—	OG6 Tb927.1.2580 ↔ Tb927.6.670 OG6 Tb927.1.2580 ↔ Tb927.11.16600 OG7 Tb927.1.2580 ↔ Tb927.6.670 OG7 Tb927.1.2580 ↔ Tb927.11.16600	Both
CFAC1_220023400 ⚠ Conserved hypothetical ATP binding protein, p	—	OG6 Tb927.3.1150 ↔ Tb927.6.670 OG6 Tb927.11.16600 ↔ Tb927.3.1150 OG7 Tb927.11.16600 ↔ Tb927.3.1150 OG7 Tb927.3.1150 ↔ Tb927.6.670	Both
CFAC1_220022000 ⚠ hypothetical protein, conserved	—	OG6 Tb927.3.1300 ↔ Tb927.6.670 OG6 Tb927.11.16600 ↔ Tb927.3.1300 OG7 Tb927.11.16600 ↔ Tb927.3.1300 OG7 Tb927.3.1300 ↔ Tb927.6.670	Both

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