CFAC1_290031700

eukaryotic translation initiation factor 5, putative

Crithidia fasciculata strain Cf-Cl OG6: OG6_101859 OG7: OG7_0007078 53 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 53 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
CFAC1_280079400 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
CFAC1_230022800 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	Both
CFAC1_280041700 ⚠ 60S ribosomal protein L10a, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006190 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006190	Both
CFAC1_300088900 ⚠ proteasome beta 2 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	Both
CFAC1_280060700 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	Both
CFAC1_130017500 ⚠ T-complex protein 1, delta subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
CFAC1_300071600 ATP-dependent RNA helicase-like protein	—	OG6 TCSYLVIO_001373 ↔ TCSYLVIO_004556	OG6
CFAC1_260055300 eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_003333 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003333 ↔ TCSYLVIO_004556	Both
CFAC1_270066000 acetyl-CoA carboxylase, putative	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_004556	Both
CFAC1_300006800 proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004556	Both
CFAC1_130007900 ⚠ proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	Both
CFAC1_300089100 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
CFAC1_220046300 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
CFAC1_230037800 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
CFAC1_170009600 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006059 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006059	Both
CFAC1_250032400 ⚠ DEAD box RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
CFAC1_200006600 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
CFAC1_250026200 ⚠ proteasome alpha 1 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
CFAC1_230050900 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
CFAC1_200010900 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	OG7
CFAC1_190010100 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
CFAC1_040007100 ⚠ DEAD/DEAH box helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
CFAC1_130028300 ⚠ proteasome subunit alpha type-5, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
CFAC1_300034600 ⚠ mitochondrial DEAD box protein, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
CFAC1_170009500 ⚠ RNA binding protein, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006059	OG7
CFAC1_110009500 ⚠ proteasome alpha 3 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
CFAC1_250026800 ⚠ proteasome beta 5 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	OG7
CFAC1_060007000 acetyltransferase, putative	—	OG6 TCSYLVIO_004519 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_004556	Both
CFAC1_290056600 RNA recognition motif. (a.k.a. RRM, RBD, or R	—	OG6 TCSYLVIO_003837 ↔ TCSYLVIO_004556	OG6
CFAC1_280055100 hypothetical protein, conserved	—	OG6 Tb927.10.2770 ↔ Tb927.11.11010 OG7 Tb927.10.2770 ↔ Tb927.11.11010	Both
CFAC1_190043700 ⚠ ATP binding protein-like protein	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_004556	Both
CFAC1_210032000 ⚠ Thioredoxin, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_004556	Both
CFAC1_260024200 spliceosome-associated protein, putative	—	OG6 TCSYLVIO_003119 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003119 ↔ TCSYLVIO_004556	Both
CFAC1_290060300 exosome subunit rrp6p homologue, putative	—	OG6 TCSYLVIO_003804 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_004556	Both
CFAC1_070008900 DEAD/DEAH box helicase, putative	—	OG6 TCSYLVIO_004479 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	Both
CFAC1_130008400 hypothetical protein, conserved	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_004556	Both
CFAC1_150026500 ⚠ T-complex protein 1, gamma subunit, putative	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
CFAC1_190019700 ⚠ chaperonin containing t-complex protein, puta	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
CFAC1_240024400 ⚠ exosome complex exonuclease RRP45 homolog, pu	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
CFAC1_300052700 ⚠ exosome-associated protein 2, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
CFAC1_200021500 hypothetical protein, conserved	—	OG6 TCSYLVIO_004312 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004312 ↔ TCSYLVIO_004556	Both
CFAC1_010005800 ⚠ proteasome beta-1 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	Both
CFAC1_090021300 translation initiation factor, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_008900 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008900	Both
CFAC1_110022300 hypothetical protein, conserved	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010606	Both
CFAC1_140014500 ⚠ 60S ribosomal protein L10a, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006190 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006190	Both
CFAC1_130026900 ⚠ proteasome alpha 2 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	Both
CFAC1_280038400 ⚠ 2-oxoglutarate dehydrogenase subunit, putativ	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005469 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005469	Both
CFAC1_080019500 splicing factor ptsr1-like protein	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_009720 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009720	Both
CFAC1_230042500 ⚠ 2-oxoglutarate dehydrogenase subunit, putativ	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005469 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005469	Both
CFAC1_300081300 ⚠ ATP-dependent RNA helicase, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005835 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	Both

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