LAEL147_000222500

mismatch repair protein MSH3, putative
Leishmania aethiopica L147 OG6: OG6_105075 OG7: OG7_0001337 17 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 17 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000574300 ⚠
replication factor C, subunit 2, putative
— OG7
LAEL147_000158900 ⚠
eukaryotic release factor 3, putative
— OG7
LAEL147_000200900 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
LAEL147_000429500 ⚠
RET2, RNA editing complex MP57
— OG7
LAEL147_000489600 ⚠
RNA polymerase I
— OG7
LAEL147_000783900 ⚠
replication factor C, subunit 3, putative
— OG7
LAEL147_000460100 ⚠
replication factor C, subunit 4, putative
— OG7
LAEL147_000246900 ⚠
ATPase family associated with various cellula
— OG7
LAEL147_000304600 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000863000 ⚠
Calponin homology (CH) domain containing prot
— Both
LAEL147_000383700 ⚠
replication factor C, subunit 1, putative
— OG7
LAEL147_000883800 ⚠
replication factor C, subunit 5, putative
— OG7
LAEL147_000289500 ⚠
Cid1 family poly A polymerase, putative
— Both
LAEL147_000793700 ⚠
elongation factor 1-alpha, putative
— Both
LAEL147_000668700 ⚠
DNA mismatch repair protein MSH2, putative
— Both
LAEL147_000234600 ⚠
ubiquitin fold modifier protein, putative
— Both
LAEL147_000330400
NIMA-related kinase, putative
— OG6
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.