LAEL147_000246900

ATPase family associated with various cellular activities (AAA), putative
Leishmania aethiopica L147 OG6: OG6_142131 OG7: OG7_0001167 125 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 125 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000109300 ⚠
Beta-lactamase superfamily domain containing
— OG7
LAEL147_000554100 ⚠
co-chaperone GrpE, putative
— OG7
LAEL147_000668700 ⚠
DNA mismatch repair protein MSH2, putative
— OG7
LAEL147_000440600 ⚠
farnesyltransferase beta subunit
— OG7
LAEL147_000270300 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LAEL147_000558500 ⚠
hypothetical protein
— OG7
LAEL147_000628800 ⚠
Leucine rich repeat, putative
— OG7
LAEL147_000772000 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000783900 ⚠
replication factor C, subunit 3, putative
— OG7
LAEL147_000554200 ⚠
heat shock protein grpe
— OG7
LAEL147_000696000 ⚠
translation initiation factor IF-2, putative
— OG7
LAEL147_000437500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000290300 ⚠
eukaryotic translation initiation factor-like
— OG7
LAEL147_000835300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000304700 ⚠
MORN repeat-containing protein
— OG7
LAEL147_000541800 ⚠
protein kinase, putative
— OG7
LAEL147_000020500 ⚠
LSM domain containing protein, putative
— OG7
LAEL147_000413600 ⚠
RNA-binding protein RBP10, putative
— OG7
LAEL147_000442400 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000271200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000723200 ⚠
eukaryotic translation initiation factor 2-al
— OG7
LAEL147_000146600 ⚠
protein kinase, putative
— OG7
LAEL147_000285100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000507700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000254400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000168000 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000026000 ⚠
ubiquitin activating enzyme, putative
— OG7
LAEL147_000103200 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LAEL147_000178200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000221000 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000767200 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000745300 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000042900 ⚠
DEAD/DEAH box helicase, putative
— OG7
LAEL147_000281700 ⚠
Suppressor-of-White-APricot splicing regulato
— OG7
LAEL147_000354500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000156500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000357200 ⚠
5'-3' exonuclease XRNC, putative
— OG7
LAEL147_000164700 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LAEL147_000082500 ⚠
TLD, putative
— OG7
LAEL147_000828800 ⚠
TLD, putative
— OG7
LAEL147_000040100 ⚠
TLD domain protein, conserved
— OG7
LAEL147_000301900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000285000 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LAEL147_000102000 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000105200 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000212800 ⚠
ecotin, putative
— OG7
LAEL147_000212900 ⚠
ecotin, putative
— OG7
LAEL147_000210800 ⚠
ecotin, putative
— OG7
LAEL147_000880100 ⚠
protein transport protein Sec23-like protein
— OG7
LAEL147_000011700 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.