LAEL147_000270300

bifunctional aminoacyl-tRNA synthetase, putative

Leishmania aethiopica L147 OG6: OG6_100749 OG7: OG7_0002333 197 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 197 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LAEL147_000551200 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_342110.1 OG7 LdBPK_181230.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_006246	Both
LAEL147_000271200 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_006238 ↔ TCSYLVIO_006246 OG6 LdBPK_181230.1 ↔ LdBPK_181300.1 OG7 LdBPK_181230.1 ↔ LdBPK_181300.1 OG7 TCSYLVIO_006238 ↔ TCSYLVIO_006246	Both
LAEL147_000686600 ⚠ Ribosome assembly protein rrb1, putative	—	OG6 TCSYLVIO_005619 ↔ TCSYLVIO_006246 OG6 LdBPK_181230.1 ↔ LdBPK_332020.1 OG7 LdBPK_181230.1 ↔ LdBPK_332020.1 OG7 TCSYLVIO_005619 ↔ TCSYLVIO_006246	Both
LAEL147_000396000 ⚠ tubulin folding cofactor D, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_242100.1 OG6 LdBPK_181230.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_242100.1 +2 more	Both
LAEL147_000340500 ⚠ guide RNA associated protein, GAP2, putative	—	OG6 LdBPK_181230.1 ↔ LdBPK_220520.1 OG6 TCSYLVIO_001262 ↔ TCSYLVIO_006246 OG7 LdBPK_181230.1 ↔ LdBPK_220520.1 OG7 TCSYLVIO_001262 ↔ TCSYLVIO_006246	Both
LAEL147_000322800 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_342110.1 OG7 LdBPK_181230.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_006246	Both
LAEL147_000725600 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_342110.1 OG6 LdBPK_181230.1 ↔ LdBPK_342110.1 OG7 LdBPK_181220.1 ↔ LdBPK_342110.1 OG7 LdBPK_181230.1 ↔ LdBPK_342110.1 +1 more	Both
LAEL147_000164700 ⚠ cysteinyl-tRNA synthetase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_181220.1 OG6 LdBPK_120255.1 ↔ LdBPK_181230.1 OG6 Tb927.10.12890 ↔ Tb927.6.950 OG7 Tb927.10.12890 ↔ Tb927.6.950 +2 more	Both
LAEL147_000011700 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_180550.1 ↔ LdBPK_181230.1 OG6 TCSYLVIO_006181 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_006181 ↔ TCSYLVIO_006246 OG7 LdBPK_180550.1 ↔ LdBPK_181230.1	Both
LAEL147_000181500 ⚠ N(2), N(2)-dimethylguanosine tRNA methyltrans	—	OG6 TCSYLVIO_002844 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_002844 ↔ TCSYLVIO_006246	Both
LAEL147_000600600 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_002919 ↔ TCSYLVIO_006246	OG7
LAEL147_000559800 ⚠ small nuclear ribonucleoprotein polypeptide e	—	OG7 LdBPK_181230.1 ↔ LdBPK_260010.1	OG7
LAEL147_000590100 ⚠ CRAL/TRIO domain containing protein, putative	—	OG7 LdBPK_181220.1 ↔ LdBPK_310320.1 OG7 LdBPK_181230.1 ↔ LdBPK_310320.1	OG7
LAEL147_000451600 ⚠ phosphatidylinositol-4-phosphate 5-kinase, pu	—	OG7 LdBPK_181220.1 ↔ LdBPK_291830.1 OG7 LdBPK_181230.1 ↔ LdBPK_291830.1	OG7
LAEL147_000418000 ⚠ LSM domain containing protein, putative	—	OG7 LdBPK_181230.1 ↔ LdBPK_260010.1	OG7
LAEL147_000508800 ⚠ eukaryotic translation initiation factor 4e,	—	OG7 LdBPK_181220.1 ↔ LdBPK_300460.1 OG7 LdBPK_181230.1 ↔ LdBPK_300460.1	OG7
LAEL147_000132600 ⚠ MORN repeat, putative	—	OG7 LdBPK_181220.1 ↔ LdBPK_291830.1 OG7 LdBPK_181230.1 ↔ LdBPK_291830.1	OG7
LAEL147_000857100 ⚠ ubiquitin protein ligase, putative	—	OG7 LdBPK_181230.1 ↔ LdBPK_321150.1	OG7
LAEL147_000090000 ⚠ ubiquitin-protein ligase-like, putative	—	OG7 LdBPK_181230.1 ↔ LdBPK_300970.1 OG7 LdBPK_161180.1 ↔ LdBPK_181220.1 OG7 LdBPK_161180.1 ↔ LdBPK_181230.1	OG7
LAEL147_000883800 ⚠ replication factor C, subunit 5, putative	—	OG7 LdBPK_181220.1 ↔ LdBPK_241010.1 OG7 LdBPK_181230.1 ↔ LdBPK_241010.1	OG7
LAEL147_000774900 ⚠ ubiquitin-protein ligase, putative	—	OG7 LdBPK_181230.1 ↔ LdBPK_321150.1	OG7
LAEL147_000471300 ⚠ eukaryotic translation initiation factor eIF-	—	OG7 LdBPK_181220.1 ↔ LdBPK_300460.1 OG7 LdBPK_181230.1 ↔ LdBPK_300460.1	OG7
LAEL147_000800400 ⚠ BRCA1 C Terminus (BRCT) domain containing pro	—	OG6 LdBPK_181220.1 ↔ LdBPK_354870.1 OG6 LdBPK_181230.1 ↔ LdBPK_354870.1 OG7 LdBPK_181220.1 ↔ LdBPK_354870.1 OG7 LdBPK_181230.1 ↔ LdBPK_354870.1	Both
LAEL147_000533600 ⚠ MORN repeat, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_291830.1 OG6 LdBPK_181230.1 ↔ LdBPK_291830.1 OG7 LdBPK_181220.1 ↔ LdBPK_291830.1 OG7 LdBPK_181230.1 ↔ LdBPK_291830.1	Both
LAEL147_000694000 ⚠ aminopeptidase, putative	—	OG7 LdBPK_110640.1 ↔ LdBPK_181220.1 OG7 LdBPK_110640.1 ↔ LdBPK_181230.1	OG7
LAEL147_000067700 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	OG7
LAEL147_000812500 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	OG7
LAEL147_000517500 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	OG7
LAEL147_000258900 ⚠ zinc-finger of a C2HC-type/Double zinc ribbon	—	OG6 TCSYLVIO_006138 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_006138 ↔ TCSYLVIO_006246	Both
LAEL147_000855700 ⚠ paraflagellar rod component, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006246	OG6
LAEL147_000339900 ⚠ Uncharacterised protein family UPF0066, putat	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_006246	Both
LAEL147_000291400 ⚠ inosine-5'-monophosphate dehydrogenase	—	OG6 LdBPK_181220.1 ↔ LdBPK_191590.1 OG6 LdBPK_181230.1 ↔ LdBPK_191590.1 OG7 LdBPK_181220.1 ↔ LdBPK_191590.1 OG7 LdBPK_181230.1 ↔ LdBPK_191590.1	Both
LAEL147_000822100 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_181220.1 ↔ LdBPK_361430.1 OG6 LdBPK_181230.1 ↔ LdBPK_361430.1 OG7 LdBPK_181220.1 ↔ LdBPK_361430.1 OG7 LdBPK_181230.1 ↔ LdBPK_361430.1	Both
LAEL147_000554200 ⚠ heat shock protein grpe	—	OG6 LdBPK_181230.1 ↔ LdBPK_300770.1 OG7 LdBPK_181230.1 ↔ LdBPK_300770.1	Both
LAEL147_000437500 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_181230.1 ↔ LdBPK_261160.1 OG7 LdBPK_181230.1 ↔ LdBPK_261160.1	Both
LAEL147_000018100 ⚠ ATP-dependent RNA helicase, putative	—	OG6 LdBPK_181230.1 ↔ LdBPK_310260.1	OG6
LAEL147_000541800 ⚠ protein kinase, putative	—	OG6 LdBPK_181230.1 ↔ LdBPK_292600.1 OG7 LdBPK_181230.1 ↔ LdBPK_292600.1	Both
LAEL147_000356500 ⚠ 5'-AMP-activated protein kinase beta subunit,	—	OG6 LdBPK_181220.1 ↔ LdBPK_230530.1 OG6 LdBPK_181230.1 ↔ LdBPK_230530.1 OG7 LdBPK_181220.1 ↔ LdBPK_230530.1 OG7 LdBPK_181230.1 ↔ LdBPK_230530.1	Both
LAEL147_000098200 ⚠ Domain of unknown function (DUF3437), putativ	—	OG6 LdBPK_071090.1 ↔ LdBPK_181220.1 OG6 LdBPK_071090.1 ↔ LdBPK_181230.1 OG7 LdBPK_071090.1 ↔ LdBPK_181220.1 OG7 LdBPK_071090.1 ↔ LdBPK_181230.1	Both
LAEL147_000156100 ⚠ PUB domain containing protein, putative	—	OG6 LdBPK_110920.1 ↔ LdBPK_181220.1 OG6 LdBPK_110920.1 ↔ LdBPK_181230.1 OG7 LdBPK_110920.1 ↔ LdBPK_181220.1 OG7 LdBPK_110920.1 ↔ LdBPK_181230.1	Both
LAEL147_000668700 ⚠ DNA mismatch repair protein MSH2, putative	—	OG6 LdBPK_181230.1 ↔ LdBPK_330420.1 OG7 LdBPK_181230.1 ↔ LdBPK_330420.1	Both
LAEL147_000105200 ⚠ WD domain, G-beta repeat, putative	—	OG6 LdBPK_080420.1 ↔ LdBPK_181220.1 OG6 LdBPK_080420.1 ↔ LdBPK_181230.1 OG7 LdBPK_080420.1 ↔ LdBPK_181220.1 OG7 LdBPK_080420.1 ↔ LdBPK_181230.1	Both
LAEL147_000268400 ⚠ 5-oxoprolinase, putative	—	OG6 LdBPK_181050.1 ↔ LdBPK_181220.1 OG6 LdBPK_181050.1 ↔ LdBPK_181230.1 OG7 LdBPK_181050.1 ↔ LdBPK_181220.1 OG7 LdBPK_181050.1 ↔ LdBPK_181230.1	Both
LAEL147_000198800 ⚠ hypothetical protein	—	OG6 TCSYLVIO_002080 ↔ TCSYLVIO_006246	OG6
LAEL147_000440600 ⚠ farnesyltransferase beta subunit	—	OG6 LdBPK_181220.1 ↔ LdBPK_261450.1 OG6 LdBPK_181230.1 ↔ LdBPK_261450.1 OG7 LdBPK_181220.1 ↔ LdBPK_261450.1 OG7 LdBPK_181230.1 ↔ LdBPK_261450.1	Both
LAEL147_000285100 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_181230.1 ↔ LdBPK_191020.1 OG7 LdBPK_181230.1 ↔ LdBPK_191020.1	Both
LAEL147_000560000 ⚠ Zinc finger, C3HC4 type (RING finger) contain	—	OG6 TCSYLVIO_003179 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_003179 ↔ TCSYLVIO_006246	Both
LAEL147_000031000 ⚠ Soluble NSF attachment protein, SNAP, putativ	—	OG6 LdBPK_020280.1 ↔ LdBPK_181220.1 OG6 LdBPK_020280.1 ↔ LdBPK_181230.1 OG7 LdBPK_020280.1 ↔ LdBPK_181220.1 OG7 LdBPK_020280.1 ↔ LdBPK_181230.1	Both
LAEL147_000024900 ⚠ DNA-damage inducible protein DDI1-like protei	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_006246	Both
LAEL147_000155800 ⚠ Leucine Rich repeat, putative	—	OG6 LdBPK_110890.1 ↔ LdBPK_181220.1 OG6 LdBPK_110890.1 ↔ LdBPK_181230.1 OG7 LdBPK_110890.1 ↔ LdBPK_181220.1 OG7 LdBPK_110890.1 ↔ LdBPK_181230.1	Both

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