LAEL147_000396000

tubulin folding cofactor D, putative

Leishmania aethiopica L147 OG6: OG6_102599 OG7: OG7_0006853 211 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 211 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LAEL147_000358000 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 LdBPK_230660.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_000055 ↔ TCSYLVIO_001302 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_001302 OG7 LdBPK_230660.1 ↔ LdBPK_242100.1	Both
LAEL147_000878700 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 LdBPK_230660.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_000055 ↔ TCSYLVIO_001302 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_001302 OG7 LdBPK_230660.1 ↔ LdBPK_242100.1	Both
LAEL147_000164700 cysteinyl-tRNA synthetase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_006977	Both
LAEL147_000295600 ⚠ developmentally regulated phosphoprotein-like	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_007262	Both
LAEL147_000105200 WD domain, G-beta repeat, putative	—	OG6 LdBPK_080420.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_010560	Both
LAEL147_000552200 hypothetical protein, conserved	—	OG6 LdBPK_242100.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003118 OG7 LdBPK_242100.1 ↔ LdBPK_300580.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003118	Both
LAEL147_000270300 ⚠ bifunctional aminoacyl-tRNA synthetase, putat	—	OG6 LdBPK_181220.1 ↔ LdBPK_242100.1 OG6 LdBPK_181230.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_242100.1 +2 more	Both
LAEL147_000725600 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 LdBPK_242100.1 ↔ LdBPK_342110.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003867 OG7 LdBPK_242100.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003867 +1 more	Both
LAEL147_000270500 ⚠ bifunctional aminoacyl-tRNA synthetase, putat	—	OG6 LdBPK_181220.1 ↔ LdBPK_242100.1 OG6 LdBPK_181230.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_242100.1 +2 more	Both
LAEL147_000270400 ⚠ Prolyl-tRNA synthetase, C-terminal, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_242100.1 OG6 LdBPK_181230.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_006246 OG7 LdBPK_181220.1 ↔ LdBPK_242100.1 +2 more	Both
LAEL147_000773700 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_001302 OG7 LdBPK_230660.1 ↔ LdBPK_242100.1	OG7
LAEL147_000322800 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003107 OG7 LdBPK_242100.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003867 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003107	Both
LAEL147_000285000 phenylalanyl-tRNA synthetase, putative	—	OG6 LdBPK_191010.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_005548	Both
LAEL147_000373600 ⚠ pyruvate dehydrogenase (lipoamide) kinase, pu	—	OG6 LdBPK_240010.1 ↔ LdBPK_242100.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_001571 OG7 LdBPK_240010.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_001571 +1 more	Both
LAEL147_000743400 ⚠ Histidine kinase-, DNA gyrase B-, and HSP90-l	—	OG7 LdBPK_240010.1 ↔ LdBPK_242100.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_001571 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_007262	OG7
LAEL147_000551200 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003107 OG7 LdBPK_242100.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003867 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003107	Both
LAEL147_000426600 ⚠ FYVE zinc finger containing protein, putative	—	OG7 LdBPK_242100.1 ↔ LdBPK_353550.1	OG7
LAEL147_000884500 ⚠ beta-adaptin, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_004597 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_004597	Both
LAEL147_000438300 ⚠ FYVE zinc finger containing protein, putative	—	OG7 LdBPK_242100.1 ↔ LdBPK_353550.1	OG7
LAEL147_000451600 ⚠ phosphatidylinositol-4-phosphate 5-kinase, pu	—	OG7 LdBPK_242100.1 ↔ LdBPK_291830.1	OG7
LAEL147_000508800 ⚠ eukaryotic translation initiation factor 4e,	—	OG7 LdBPK_242100.1 ↔ LdBPK_300460.1	OG7
LAEL147_000439900 ⚠ MORN repeat/FYVE zinc finger containing prote	—	OG7 LdBPK_242100.1 ↔ LdBPK_353550.1	OG7
LAEL147_000132600 ⚠ MORN repeat, putative	—	OG7 LdBPK_242100.1 ↔ LdBPK_291830.1	OG7
LAEL147_000471300 ⚠ eukaryotic translation initiation factor eIF-	—	OG7 LdBPK_242100.1 ↔ LdBPK_300460.1	OG7
LAEL147_000558500 ⚠ hypothetical protein	—	OG7 LdBPK_161180.1 ↔ LdBPK_242100.1	OG7
LAEL147_000558400 ⚠ WW domain containing protein, putative	—	OG7 LdBPK_161180.1 ↔ LdBPK_242100.1	OG7
LAEL147_000090000 ⚠ ubiquitin-protein ligase-like, putative	—	OG7 LdBPK_161180.1 ↔ LdBPK_242100.1	OG7
LAEL147_000556500 ⚠ ubiquitin-protein ligase, putative	—	OG7 LdBPK_161180.1 ↔ LdBPK_242100.1	OG7
LAEL147_000783900 ⚠ replication factor C, subunit 3, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_242100.1	OG7
LAEL147_000460100 ⚠ replication factor C, subunit 4, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_242100.1	OG7
LAEL147_000246900 ⚠ ATPase family associated with various cellula	—	OG7 LdBPK_241010.1 ↔ LdBPK_242100.1	OG7
LAEL147_000304600 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_241010.1 ↔ LdBPK_242100.1	OG7
LAEL147_000574300 ⚠ replication factor C, subunit 2, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_242100.1	OG7
LAEL147_000883800 ⚠ replication factor C, subunit 5, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_242100.1	OG7
LAEL147_000428700 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_002376 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_004468 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_002376	Both
LAEL147_000747600 nucleolar protein family a, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003690 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003690	Both
LAEL147_000560000 Zinc finger, C3HC4 type (RING finger) contain	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003179 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003179	Both
LAEL147_000761400 ⚠ NADH-dependent fumarate reductase, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_005116 +2 more	Both
LAEL147_000842900 ATP synthase, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_009199 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_009199	Both
LAEL147_000740900 vacuolar ATP synthase catalytic subunit A, pu	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003744 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003744	Both
LAEL147_000855700 paraflagellar rod component, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_004736	OG6
LAEL147_000044000 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_004468 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_004468 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_002376	Both
LAEL147_000103200 ⚠ ubiquitin-activating enzyme-like protein	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_010542	Both
LAEL147_000511500 ⚠ Hsp70 protein, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_002696	OG6
LAEL147_000202300 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_001302 ↔ TCSYLVIO_009362	OG7
LAEL147_000445100 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003586 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003586	Both
LAEL147_000705700 ⚠ tRNA pseudouridine synthase, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_004376 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_004376	Both
LAEL147_000834900 dipeptidyl-peptidase 8-like serine peptidase,	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_007536 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_007536	Both
LAEL147_000756200 vacuolar ATP synthase subunit d, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_005104 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_005104	Both
LAEL147_000550000 kinesin, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003093	OG6

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