LAEL147_000743400

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative
Leishmania aethiopica L147 OG6: OG6_146732 OG7: OG7_0002830 155 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 155 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000285000 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LAEL147_000164700 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LAEL147_000540600 ⚠
aspartyl aminopeptidase, putative
— OG7
LAEL147_000373600 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LAEL147_000295600 ⚠
developmentally regulated phosphoprotein-like
— OG7
LAEL147_000358000 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LAEL147_000878700 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LAEL147_000773700 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LAEL147_000396000 ⚠
tubulin folding cofactor D, putative
— OG7
LAEL147_000322800 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LAEL147_000551200 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LAEL147_000725600 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LAEL147_000026000 ⚠
ubiquitin activating enzyme, putative
— OG7
LAEL147_000761500 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LAEL147_000757700 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LAEL147_000761400 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LAEL147_000096500 ⚠
flavoprotein subunit-like protein
— OG7
LAEL147_000468700 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000284300 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LAEL147_000417900 ⚠
Leucine-rich repeat, putative
— OG7
LAEL147_000210500 ⚠
ribonucleoprotein p18, mitochondrial precurso
— OG7
LAEL147_000613000 ⚠
uridine kinase-like protein
— OG7
LAEL147_000140400 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAEL147_000172200 ⚠
arginine N-methyltransferase-like protein
— OG7
LAEL147_000522500 ⚠
heat shock protein 90, putative
— +2 more OG7
LAEL147_000434600 ⚠
heat shock 70 protein-like protein
— OG7
LAEL147_000333100 ⚠
ATP synthase F1 subunit gamma protein, putati
— OG7
LAEL147_000144300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000081700 ⚠
arginine N-methyltransferase, type III, putat
— OG7
LAEL147_000351600 ⚠
GDP-mannose pyrophosphorylase
— OG7
LAEL147_000622600 ⚠
U2 small nuclear ribonucleoprotein 40K, putat
— OG7
LAEL147_000717000 ⚠
inositol 5-phosphatase-like protein
— OG7
LAEL147_000133600 ⚠
Exonuclease, putative
— OG7
LAEL147_000511600 ⚠
heat-shock protein hsp70, putative
— OG7
LAEL147_000354000 ⚠
pteridine reductase 1
— OG7
LAEL147_000692300 ⚠
heat shock protein, putative
— +2 more OG7
LAEL147_000668200 ⚠
heat shock protein 83-17
— +2 more OG7
LAEL147_000528100 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LAEL147_000514600 ⚠
transcription factor-like protein
— OG7
LAEL147_000382000 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LAEL147_000090300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000494700 ⚠
heat-shock protein hsp70, putative
— OG7
LAEL147_000870000 ⚠
beta-adaptin protein, putative
— OG7
LAEL147_000745600 ⚠
GRIP domain containing protein, putative
— OG7
LAEL147_000491500 ⚠
oxidoreductase-like protein
— OG7
LAEL147_000078200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000347400 ⚠
fk506-binding protein 1-like protein
— OG7
LAEL147_000158800 ⚠
protein transport protein SEC31, putative
— OG7
LAEL147_000037000 ⚠
Leucine Rich repeats (2 copies), putative
— OG7
LAEL147_000041700 ⚠
arginine N-methyltransferase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.