LAEL147_000522500

heat shock protein 90, putative

Leishmania aethiopica L147 OG6: OG6_100204 OG7: OG7_0001978 167 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 167 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LAEL147_000011700 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_006181 ↔ TCSYLVIO_010666 OG7 Tb927.10.14030 ↔ Tb927.3.3580	OG7
LAEL147_000692300 ⚠ heat shock protein, putative	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
LAEL147_000206000 ⚠ tyrosyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	OG7
LAEL147_000218900 ⚠ glutamate dehydrogenase	—	OG6 LdBPK_151070.1 ↔ LdBPK_330360.1 OG6 TCSYLVIO_002205 ↔ TCSYLVIO_007064 OG6 TCSYLVIO_007064 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007064 ↔ TCSYLVIO_009400 +6 more	Both
LAEL147_000366700 ⚠ coronin, putative	—	OG6 TCSYLVIO_000174 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_000174 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_000174 ↔ TCSYLVIO_009151 OG6 Tb927.10.10960 ↔ Tb927.8.3100 +4 more	Both
LAEL147_000235500 ⚠ tyrosyl or methionyl-tRNA synthetase-like pro	—	OG6 LdBPK_161170.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	Both
LAEL147_000338800 ⚠ Putative tRNA binding domain containing prote	—	OG6 LdBPK_161170.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	Both
LAEL147_000668200 ⚠ heat shock protein 83-17	—	OG6 LdBPK_290790.1 ↔ LdBPK_330360.1 OG6 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +12 more	Both
LAEL147_000105200 ⚠ WD domain, G-beta repeat, putative	—	OG6 TCSYLVIO_009151 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_009400 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_008621 ↔ TCSYLVIO_010560 OG7 Tb927.3.3580 ↔ Tb927.5.3260 +3 more	Both
LAEL147_000316500 ⚠ vacuolar sorting-associated-like protein	—	OG7 LdBPK_210530.1 ↔ LdBPK_332520.1	OG7
LAEL147_000808700 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-bisphos	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009151	OG7
LAEL147_000044000 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009151	OG7
LAEL147_000096100 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009151	OG7
LAEL147_000147300 ⚠ NGG1 interacting factor 3-like protein	—	OG7 TCSYLVIO_001715 ↔ TCSYLVIO_005578	OG7
LAEL147_000677000 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004910 ↔ TCSYLVIO_005578	OG7
LAEL147_000717000 ⚠ inositol 5-phosphatase-like protein	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
LAEL147_000382000 ⚠ inositol polyphosphate phosphatase, putative	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
LAEL147_000819600 ⚠ endonuclease/exonuclease/phosphatase, putativ	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
LAEL147_000794500 ⚠ synaptojanin (N-terminal domain), putative	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
LAEL147_000220100 ⚠ inositol/phosphatidylinositol phosphatase, pu	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
LAEL147_000773700 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_009151	OG7
LAEL147_000726700 ⚠ Elongation factor Tu GTP binding domain conta	—	OG7 LdBPK_330360.1 ↔ LdBPK_332930.1	OG7
LAEL147_000768800 ⚠ 60S ribosomal protein L5, putative	—	OG7 TCSYLVIO_001078 ↔ TCSYLVIO_010666	OG7
LAEL147_000763800 ⚠ peroxisome targeting signal 1 receptor, putat	—	OG7 TCSYLVIO_005361 ↔ TCSYLVIO_005578	OG7
LAEL147_000870300 ⚠ isoleucyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005578	OG7
LAEL147_000038100 ⚠ fatty acyl CoA syntetase 1, putative	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
LAEL147_000023800 ⚠ fatty acyl CoA syntetase 1, putative	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
LAEL147_000023900 ⚠ fatty acyl CoA syntetase 1, putative	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
LAEL147_000024100 ⚠ long-chain-fatty-acid-CoA ligase, putative	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
LAEL147_000023600 ⚠ fatty acyl CoA syntetase 1, putative	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
LAEL147_000024000 ⚠ fatty acyl CoA syntetase 1, putative	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
LAEL147_000641700 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004111 ↔ TCSYLVIO_011092	OG7
LAEL147_000132100 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_008446 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008446 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_008446 ↔ TCSYLVIO_009151	OG7
LAEL147_000631300 ⚠ Staphylococcal nuclease homologue/Tudor domai	—	OG7 Tb927.11.14190 ↔ Tb927.11.2650	OG7
LAEL147_000434600 ⚠ heat shock 70 protein-like protein	—	OG7 Tb927.3.3580 ↔ Tb927.9.9860 OG7 Tb927.11.7460 ↔ Tb927.3.3580	OG7
LAEL147_000511600 ⚠ heat-shock protein hsp70, putative	—	OG7 Tb927.3.3580 ↔ Tb927.9.9860 OG7 Tb927.11.7460 ↔ Tb927.3.3580	OG7
LAEL147_000494700 ⚠ heat-shock protein hsp70, putative	—	OG7 Tb927.3.3580 ↔ Tb927.9.9860 OG7 Tb927.11.7460 ↔ Tb927.3.3580	OG7
LAEL147_000511500 ⚠ Hsp70 protein, putative	—	OG7 Tb927.3.3580 ↔ Tb927.9.9860 OG7 Tb927.11.7460 ↔ Tb927.3.3580	OG7
LAEL147_000271700 ⚠ heat shock protein 110, putative	—	OG7 Tb927.3.3580 ↔ Tb927.9.9860 OG7 Tb927.11.7460 ↔ Tb927.3.3580	OG7
LAEL147_000025300 ⚠ HSP70-like protein	—	OG7 Tb927.3.3580 ↔ Tb927.9.9860 OG7 Tb927.11.7460 ↔ Tb927.3.3580	OG7
LAEL147_000799400 ⚠ Hsp70 protein, putative	—	OG7 Tb927.3.3580 ↔ Tb927.9.9860 OG7 Tb927.11.7460 ↔ Tb927.3.3580	OG7
LAEL147_000438100 ⚠ heat-shock protein hsp70, putative	—	OG7 Tb927.3.3580 ↔ Tb927.9.9860 OG7 Tb927.11.7460 ↔ Tb927.3.3580	OG7
LAEL147_000551200 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005578	OG7
LAEL147_000774500 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009151	OG7
LAEL147_000468000 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009151	OG7
LAEL147_000164100 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009151	OG7
LAEL147_000597200 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_008414	OG7
LAEL147_000026000 ⚠ ubiquitin activating enzyme, putative	—	OG7 TCSYLVIO_009151 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_009400 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_008621 ↔ TCSYLVIO_010542	OG7
LAEL147_000194900 ⚠ N-terminal conserved domain of Nudc./CS domai	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_010327	OG7
LAEL147_000597400 ⚠ Peptidase family M20/M25/M40, putative	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_008414	OG7

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