LAEL147_000870300

isoleucyl-tRNA synthetase, putative

Leishmania aethiopica L147 OG6: OG6_100811 OG7: OG7_0003029 202 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 202 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LAEL147_000311000 ⚠ hypothetical protein	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LAEL147_000152900 ⚠ aminopeptidase, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LAEL147_000153000 ⚠ aminopeptidase, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LAEL147_000183200 leucyl-tRNA synthetase, putative	—	OG6 Tb927.10.9190 ↔ Tb927.11.3730 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.11.3730 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004705	Both
LAEL147_000597300 ⚠ hypothetical protein	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LAEL147_000597400 ⚠ Peptidase family M20/M25/M40, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LAEL147_000725600 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 Tb927.10.9190 ↔ Tb927.4.2310 OG6 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 +1 more	Both
LAEL147_000235500 ⚠ tyrosyl or methionyl-tRNA synthetase-like pro	—	OG6 Tb927.10.9190 ↔ Tb927.8.5330 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010624 +1 more	Both
LAEL147_000206000 ⚠ tyrosyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010624 OG7 Tb927.10.9190 ↔ Tb927.8.5330	Both
LAEL147_000338800 ⚠ Putative tRNA binding domain containing prote	—	OG6 Tb927.10.9190 ↔ Tb927.8.5330 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010624 +1 more	Both
LAEL147_000694000 ⚠ aminopeptidase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005560 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LAEL147_000597200 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LAEL147_000561600 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LAEL147_000369600 ⚠ aminoacyclase, putative	—	OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	OG7
LAEL147_000170700 ⚠ N-acyl-L-amino acid amidohydrolase	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LAEL147_000322800 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.4.2310	Both
LAEL147_000551200 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.4.2310	Both
LAEL147_000753500 hypothetical protein, conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005084 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005084	Both
LAEL147_000083200 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_365870.1	OG7
LAEL147_000455900 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_365870.1	OG7
LAEL147_000884700 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_080820.1 ↔ LdBPK_365870.1	OG7
LAEL147_000172500 ⚠ MYND finger/SET domain containing protein, pu	—	OG7 LdBPK_080820.1 ↔ LdBPK_365870.1	OG7
LAEL147_000670000 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_365870.1	OG7
LAEL147_000644100 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_070810.1 ↔ LdBPK_365870.1	OG7
LAEL147_000049200 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004705	OG7
LAEL147_000484800 ⚠ rrp44p homologue, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004705	OG7
LAEL147_000165200 ornithine decarboxylase, putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_365870.1 OG7 LdBPK_120105.1 ↔ LdBPK_365870.1	Both
LAEL147_000403900 Translation initiation factor SUI1, putative	—	OG6 LdBPK_250420.1 ↔ LdBPK_365870.1 OG7 LdBPK_250420.1 ↔ LdBPK_365870.1	Both
LAEL147_000045300 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004705	Both
LAEL147_000148100 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004705	Both
LAEL147_000664000 Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_004705	Both
LAEL147_000554100 ⚠ co-chaperone GrpE, putative	—	OG6 TCSYLVIO_003139 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003139 ↔ TCSYLVIO_004705	Both
LAEL147_000520800 ⚠ NF-X1 type zinc finger containing protein, pu	—	OG6 LdBPK_290620.1 ↔ LdBPK_365870.1 OG7 LdBPK_290620.1 ↔ LdBPK_365870.1	Both
LAEL147_000485900 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004705	Both
LAEL147_000796900 ⚠ sm-f snRNP core complex protein, putative	—	OG6 LdBPK_354530.1 ↔ LdBPK_365870.1 OG7 LdBPK_354530.1 ↔ LdBPK_365870.1 OG7 LdBPK_301270.1 ↔ LdBPK_365870.1	Both
LAEL147_000341300 hypothetical protein, conserved	—	OG6 LdBPK_220710.1 ↔ LdBPK_365870.1 OG7 LdBPK_220710.1 ↔ LdBPK_365870.1	Both
LAEL147_000425700 hypothetical protein, conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010323 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010323	Both
LAEL147_000692300 ⚠ heat shock protein, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005578 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005578	Both
LAEL147_000797800 Cysteine-rich motif following a subset of SET	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005710	Both
LAEL147_000507400 ⚠ serine hydroxymethyltransferase (SHMT-L)	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010621	Both
LAEL147_000422300 hypothetical protein, conserved	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006404 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006404	Both
LAEL147_000515000 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010724 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010724	Both
LAEL147_000266700 cyclosporin 16, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006217	OG6
LAEL147_000753300 Thioredoxin, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005083 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005083	Both
LAEL147_000194900 ⚠ N-terminal conserved domain of Nudc./CS domai	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_010327 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_010327	Both
LAEL147_000542400 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_004998 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_004998	Both
LAEL147_000458000 nucleoporin, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007387 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007387	Both
LAEL147_000283400 ⚠ ABC transport system ATP-binding protein, put	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006012 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006012	Both
LAEL147_000259100 ⚠ alpha glucosidase II subunit, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006140 OG6 TCSYLVIO_004705 ↔ TCSYLVIO_006141 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006140 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_006141	Both
LAEL147_000305200 Pre-mRNA-splicing factor 38, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007337 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007337	Both

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