LAEL147_000266700

cyclosporin 16, putative
Leishmania aethiopica L147 OG6: OG6_152675 OG7: OG7_0000556 80 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 80 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000082600
glucosamine-fructose-6-phosphate aminotransfe
— OG6
LAEL147_000346000 ⚠
translation initiation factor IF-2, putative
— OG6
LAEL147_000259100
alpha glucosidase II subunit, putative
— OG6
LAEL147_000258200
kinetoplast polyadenylation/uridylation facto
— OG6
LAEL147_000581700
UV excision repair RAD23-like protein
— OG6
LAEL147_000583300
DNA ligase I, putative
— OG6
LAEL147_000264700
HEAT repeat, putative
— OG6
LAEL147_000337200
hypothetical protein, conserved
— OG6
LAEL147_000155800
Leucine Rich repeat, putative
— OG6
LAEL147_000556500
ubiquitin-protein ligase, putative
— OG6
LAEL147_000345100 ⚠
translation initiation factor IF-2, putative
— OG6
LAEL147_000181300
hypothetical protein, conserved
— OG6
LAEL147_000532400
XPC-binding domain/UBA/TS-N domain containing
— OG6
LAEL147_000014500
calreticulin, putative
— OG6
LAEL147_000741800
hypothetical protein, conserved
— OG6
LAEL147_000007000
hypothetical protein, conserved
— OG6
LAEL147_000536900
serine/threonine protein kinase, putative
— OG6
LAEL147_000725600
asparaginyl-tRNA synthetase, putative
— OG6
LAEL147_000753000
hypothetical protein, conserved
— OG6
LAEL147_000778100
acyl-CoA dehydrogenase, putative
— OG6
LAEL147_000264000
Zn-finger in Ran binding protein and others/F
— OG6
LAEL147_000283400
ABC transport system ATP-binding protein, put
— OG6
LAEL147_000045300 ⚠
inorganic pyrophosphatase, putative
— OG6
LAEL147_000148100 ⚠
acidocalcisomal pyrophosphatase
— OG6
LAEL147_000840000
hypothetical protein, conserved
— OG6
LAEL147_000664000
Gar1/Naf1 RNA binding region containing prote
— OG6
LAEL147_000380100
MCAK-like kinesin, putative
— OG6
LAEL147_000485900
DIS3-like exonuclease, putative
— OG6
LAEL147_000348700
alanyl-tRNA synthetase, putative
— OG6
LAEL147_000401300
cleavage and polyadenylation specificity fact
— OG6
LAEL147_000435600
Glucosidase II beta subunit-like/Glucosidase
— OG6
LAEL147_000870300
isoleucyl-tRNA synthetase, putative
— OG6
LAEL147_000067600
hypothetical protein, conserved
— OG6
LAEL147_000479700 ⚠
TPR-repeat protein, putative
— OG6
LAEL147_000807600 ⚠
stress-inducible protein STI1 homolog
— OG6
LAEL147_000542400 ⚠
NOL1/NOP2/sun family, putative
— OG6
LAEL147_000831700 ⚠
NOL1/NOP2/sun family, putative
— OG6
LAEL147_000438600
Cupin-like domain containing protein, putativ
— OG6
LAEL147_000537900
UDP-glucose:Glycoprotein Glucosyltransferase,
— OG6
LAEL147_000753500
hypothetical protein, conserved
— OG6
LAEL147_000618500
Component of IIS longevity pathway SMK-1, put
— OG6
LAEL147_000257900
Rab-GTPase-TBC domain containing protein, put
— OG6
LAEL147_000428800 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG6
LAEL147_000574000 ⚠
formate--tetrahydrofolate ligase
— OG6
LAEL147_000558800
importin alpha, putative
— OG6
LAEL147_000875300
disgorgin, putative
— OG6
LAEL147_000571000
SET domain containing protein, putative
— OG6
LAEL147_000706000 ⚠
deoxyhypusine synthase
— OG6
LAEL147_000335700
hypothetical protein, conserved
— OG6
LAEL147_000295200 ⚠
deoxyhypusine synthase, putative
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.