LAEL147_000706000

deoxyhypusine synthase

Leishmania aethiopica L147 OG6: OG6_101093 OG7: OG7_0005231 135 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 135 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LAEL147_000295200 ⚠ deoxyhypusine synthase, putative	—	OG6 TCSYLVIO_004558 ↔ TCSYLVIO_007258 OG6 Tb927.1.870 ↔ Tb927.10.2750 OG7 Tb927.1.870 ↔ Tb927.10.2750 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007258	Both
LAEL147_000551200 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007258	OG7
LAEL147_000155800 ⚠ Leucine Rich repeat, putative	—	OG6 TCSYLVIO_001642 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001642 ↔ TCSYLVIO_004558	Both
LAEL147_000337200 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001161 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001161 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001161 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001161 ↔ TCSYLVIO_007258	Both
LAEL147_000583300 ⚠ DNA ligase I, putative	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003375 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_007258	Both
LAEL147_000581700 ⚠ UV excision repair RAD23-like protein	—	OG6 TCSYLVIO_003361 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003361 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_007258	Both
LAEL147_000258200 ⚠ kinetoplast polyadenylation/uridylation facto	—	OG6 TCSYLVIO_000834 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_000834 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_007258	Both
LAEL147_000075300 ⚠ serine peptidase, clan SC, family S9A-like pr	—	OG6 TCSYLVIO_006546 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006546 ↔ TCSYLVIO_007258	Both
LAEL147_000075700 ⚠ serine peptidase, clan SC, family S9A-like pr	—	OG6 TCSYLVIO_006546 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006546 ↔ TCSYLVIO_007258	Both
LAEL147_000346000 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007258	Both
LAEL147_000339900 ⚠ Uncharacterised protein family UPF0066, putat	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_007258	Both
LAEL147_000345100 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007258	Both
LAEL147_000537900 ⚠ UDP-glucose:Glycoprotein Glucosyltransferase,	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_004363 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_007258	Both
LAEL147_000438600 ⚠ Cupin-like domain containing protein, putativ	—	OG6 TCSYLVIO_002279 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002279 ↔ TCSYLVIO_004558	Both
LAEL147_000807600 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007258	OG6
LAEL147_000479700 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007258	OG6
LAEL147_000067600 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007258	Both
LAEL147_000348700 ⚠ alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007258	Both
LAEL147_000485900 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007258 +4 more	Both
LAEL147_000664000 ⚠ Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007258	Both
LAEL147_000148100 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
LAEL147_000045300 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
LAEL147_000503400 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LAEL147_000007800 ⚠ serine/threonine protein kinase sos2, putativ	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LAEL147_000816800 ⚠ SNF1-related protein kinases, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LAEL147_000484800 ⚠ rrp44p homologue, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007258	OG7
LAEL147_000684500 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LAEL147_000264500 ⚠ serine/threonine kinase-like protein, putativ	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LAEL147_000313300 ⚠ serine/threonine-protein kinase-like protein	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LAEL147_000097700 ⚠ serine/threonine kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LAEL147_000049200 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007258	OG7
LAEL147_000737800 ⚠ cleavage and polyadenylation specificity fact	—	OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005414	OG7
LAEL147_000037400 ⚠ ATP-binding cassette protein subfamily F, mem	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
LAEL147_000668100 ⚠ ATP-binding cassette sub-family F member 1, p	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
LAEL147_000875400 ⚠ rab-like GTPase activating protein, putative	—	OG7 TCSYLVIO_004663 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_004663	OG7
LAEL147_000235500 ⚠ tyrosyl or methionyl-tRNA synthetase-like pro	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010624	OG7
LAEL147_000786400 ⚠ zinc finger protein, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LAEL147_000354300 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010724 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010724	OG7
LAEL147_000606500 ⚠ dihydrouridine synthase (Dus), putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_009102	OG7
LAEL147_000576500 ⚠ GTPase activator-like protein	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_008881	OG7
LAEL147_000439900 ⚠ MORN repeat/FYVE zinc finger containing prote	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LAEL147_000438300 ⚠ FYVE zinc finger containing protein, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LAEL147_000426600 ⚠ FYVE zinc finger containing protein, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LAEL147_000204100 ⚠ ras-like small GTPases, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LAEL147_000715800 ⚠ Dihydrouridine synthase (Dus), putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_009102	OG7
LAEL147_000338800 ⚠ Putative tRNA binding domain containing prote	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010624	OG7
LAEL147_000681100 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_007401 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007401	OG7
LAEL147_000284400 ⚠ FYVE zinc finger containing protein, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LAEL147_000553700 ⚠ nuclear movement protein, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010327 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010327	OG7
LAEL147_000218600 ⚠ Rad9, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007065	OG7

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