LAEL147_000485900

DIS3-like exonuclease, putative
Leishmania aethiopica L147 OG6: OG6_102526 OG7: OG7_0002439 240 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 240 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000797800 ⚠
Cysteine-rich motif following a subset of SET
— +1 more Both
LAEL147_000311000 ⚠
hypothetical protein
— Both
LAEL147_000597300 ⚠
hypothetical protein
— Both
LAEL147_000597400 ⚠
Peptidase family M20/M25/M40, putative
— Both
LAEL147_000369600 ⚠
aminoacyclase, putative
— OG7
LAEL147_000214800 ⚠
hypothetical protein, conserved
— Both
LAEL147_000153000 ⚠
aminopeptidase, putative
— OG7
LAEL147_000152900 ⚠
aminopeptidase, putative
— OG7
LAEL147_000597200 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LAEL147_000561600 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LAEL147_000681100 ⚠
protein kinase, putative
— OG7
LAEL147_000408800 ⚠
protein kinase, putative
— +1 more Both
LAEL147_000694000 ⚠
aminopeptidase, putative
— +1 more Both
LAEL147_000170700 ⚠
N-acyl-L-amino acid amidohydrolase
— Both
LAEL147_000877000 ⚠
flagellum transition zone component, putative
— OG7
LAEL147_000719900 ⚠
EAP30/Vps36 family, putative
— OG7
LAEL147_000140400 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAEL147_000284300 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LAEL147_000177500 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
LAEL147_000719100 ⚠
D-isomer specific 2-hydroxyacid dehydrogenase
— OG7
LAEL147_000269100 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LAEL147_000854200 ⚠
glycosyl hydrolase-like protein
— OG7
LAEL147_000097700 ⚠
serine/threonine kinase, putative
— OG7
LAEL147_000058400 ⚠
tRNA nucleotidyltransferase, putative
— OG7
LAEL147_000269000 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeat, pu
— OG7
LAEL147_000313300 ⚠
serine/threonine-protein kinase-like protein
— OG7
LAEL147_000554200 ⚠
heat shock protein grpe
— OG7
LAEL147_000782000 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000284400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000715800 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAEL147_000558500 ⚠
hypothetical protein
— OG7
LAEL147_000271300 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LAEL147_000418300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000739500 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LAEL147_000737800 ⚠
cleavage and polyadenylation specificity fact
— OG7
LAEL147_000204100 ⚠
ras-like small GTPases, putative
— OG7
LAEL147_000426600 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000438300 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000037400 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LAEL147_000816800 ⚠
SNF1-related protein kinases, putative
— OG7
LAEL147_000260500 ⚠
RNA-binding protein 29, putative
— OG7
LAEL147_000665800 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LAEL147_000777400 ⚠
ankyrin repeat protein, putative
— OG7
LAEL147_000007800 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
LAEL147_000439900 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAEL147_000323300 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LAEL147_000878700 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LAEL147_000773700 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LAEL147_000668200 ⚠
heat shock protein 83-17
— OG7
LAEL147_000719000 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.