LAEL147_000797800

Cysteine-rich motif following a subset of SET domains/SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain containing protein, putative

Leishmania aethiopica L147 OG6: OG6_108008 OG7: OG7_0013020 194 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 194 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LAEL147_000049200 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005710 OG7 LdBPK_280470.1 ↔ LdBPK_354620.1	OG7
LAEL147_000681100 ⚠ protein kinase, putative	—	OG6 LdBPK_331490.1 ↔ LdBPK_354620.1 OG7 TCSYLVIO_005710 ↔ TCSYLVIO_007401 OG7 LdBPK_331490.1 ↔ LdBPK_354620.1	Both
LAEL147_000484800 ⚠ rrp44p homologue, putative	—	OG6 LdBPK_280470.1 ↔ LdBPK_354620.1 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005710 OG7 LdBPK_280470.1 ↔ LdBPK_354620.1	Both
LAEL147_000485900 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_005710 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005710 +1 more	Both
LAEL147_000408800 ⚠ protein kinase, putative	—	OG6 TCSYLVIO_005710 ↔ TCSYLVIO_007401 OG7 TCSYLVIO_005710 ↔ TCSYLVIO_007401 OG7 LdBPK_331490.1 ↔ LdBPK_354620.1	Both
LAEL147_000597400 ⚠ Peptidase family M20/M25/M40, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_354620.1 OG6 LdBPK_201740.1 ↔ LdBPK_354620.1 OG7 LdBPK_201720.1 ↔ LdBPK_354620.1 OG7 LdBPK_201740.1 ↔ LdBPK_354620.1	Both
LAEL147_000831400 ⚠ DEAD box RNA helicase, putative	—	OG7 LdBPK_353150.1 ↔ LdBPK_354620.1 OG7 LdBPK_282220.1 ↔ LdBPK_354620.1	OG7
LAEL147_000064000 ⚠ GTPase, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_354620.1	OG7
LAEL147_000439400 ⚠ guanine nucleotide-binding protein-like prote	—	OG7 LdBPK_050200.1 ↔ LdBPK_354620.1	OG7
LAEL147_000692400 ⚠ ras-like small GTPases, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_354620.1	OG7
LAEL147_000472400 ⚠ zinc finger containing protein, putative	—	OG7 LdBPK_271580.1 ↔ LdBPK_354620.1	OG7
LAEL147_000737800 ⚠ cleavage and polyadenylation specificity fact	—	OG7 TCSYLVIO_005414 ↔ TCSYLVIO_005710	OG7
LAEL147_000247800 ⚠ Acyl CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_354620.1	OG7
LAEL147_000728700 ⚠ acyl-CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_354620.1	OG7
LAEL147_000248000 ⚠ Acyl CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_354620.1	OG7
LAEL147_000158900 ⚠ eukaryotic release factor 3, putative	—	OG7 LdBPK_354220.1 ↔ LdBPK_354620.1	OG7
LAEL147_000537400 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_130530.1 ↔ LdBPK_354620.1	OG7
LAEL147_000330400 NIMA-related kinase, putative	—	OG6 LdBPK_211870.1 ↔ LdBPK_354620.1	OG6
LAEL147_000165200 ornithine decarboxylase, putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_354620.1 OG7 LdBPK_120105.1 ↔ LdBPK_354620.1	Both
LAEL147_000301000 conserved protein, unknown function	—	OG6 LdBPK_200770.1 ↔ LdBPK_354620.1 OG7 LdBPK_200770.1 ↔ LdBPK_354620.1	Both
LAEL147_000045300 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_005710	Both
LAEL147_000148100 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_005710	Both
LAEL147_000877000 flagellum transition zone component, putative	—	OG6 LdBPK_354620.1 ↔ LdBPK_366480.1 OG7 LdBPK_354620.1 ↔ LdBPK_366480.1	Both
LAEL147_000664000 Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_005710	Both
LAEL147_000170700 ⚠ N-acyl-L-amino acid amidohydrolase	—	OG6 LdBPK_201720.1 ↔ LdBPK_354620.1 OG6 LdBPK_201740.1 ↔ LdBPK_354620.1 OG7 LdBPK_201720.1 ↔ LdBPK_354620.1 OG7 LdBPK_201740.1 ↔ LdBPK_354620.1	Both
LAEL147_000561600 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_354620.1 OG6 LdBPK_201740.1 ↔ LdBPK_354620.1 OG7 LdBPK_201720.1 ↔ LdBPK_354620.1 OG7 LdBPK_201740.1 ↔ LdBPK_354620.1	Both
LAEL147_000476200 ⚠ ribonucleoside-diphosphate reductase small ch	—	OG6 LdBPK_221110.1 ↔ LdBPK_354620.1 OG7 LdBPK_221110.1 ↔ LdBPK_354620.1	Both
LAEL147_000753500 hypothetical protein, conserved	—	OG6 TCSYLVIO_005084 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_005084 ↔ TCSYLVIO_005710	Both
LAEL147_000690900 glycosyl hydrolase-like protein	—	OG6 LdBPK_332390.1 ↔ LdBPK_354620.1 OG7 LdBPK_332390.1 ↔ LdBPK_354620.1	Both
LAEL147_000537900 UDP-glucose:Glycoprotein Glucosyltransferase,	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_005710	Both
LAEL147_000831700 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_005710	Both
LAEL147_000542400 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_005710	Both
LAEL147_000719900 EAP30/Vps36 family, putative	—	OG6 LdBPK_341570.1 ↔ LdBPK_354620.1 OG7 LdBPK_341570.1 ↔ LdBPK_354620.1	Both
LAEL147_000839900 ⚠ pre-mRNA splicing factor ATP-dependent RNA he	—	OG6 LdBPK_241120.1 ↔ LdBPK_354620.1	OG6
LAEL147_000227600 ⚠ Met-10+ like-protein, putative	—	OG6 LdBPK_160320.1 ↔ LdBPK_354620.1 OG7 LdBPK_160320.1 ↔ LdBPK_354620.1	Both
LAEL147_000384800 ⚠ pre-mRNA splicing factor, putative	—	OG6 LdBPK_241120.1 ↔ LdBPK_354620.1	OG6
LAEL147_000761600 ⚠ pre-mRNA splicing factor ATP-dependent RNA he	—	OG6 LdBPK_241120.1 ↔ LdBPK_354620.1	OG6
LAEL147_000345600 ⚠ ribonucleoside-diphosphate reductase small ch	—	OG6 LdBPK_221110.1 ↔ LdBPK_354620.1 OG7 LdBPK_221110.1 ↔ LdBPK_354620.1	Both
LAEL147_000870300 isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005710	Both
LAEL147_000090900 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 LdBPK_353150.1 ↔ LdBPK_354620.1 OG7 LdBPK_282220.1 ↔ LdBPK_354620.1	OG7
LAEL147_000597300 ⚠ hypothetical protein	—	OG6 LdBPK_201720.1 ↔ LdBPK_354620.1 OG6 LdBPK_201740.1 ↔ LdBPK_354620.1 OG7 LdBPK_201720.1 ↔ LdBPK_354620.1 OG7 LdBPK_201740.1 ↔ LdBPK_354620.1	Both
LAEL147_000311000 ⚠ hypothetical protein	—	OG6 LdBPK_201720.1 ↔ LdBPK_354620.1 OG6 LdBPK_201740.1 ↔ LdBPK_354620.1 OG7 LdBPK_201720.1 ↔ LdBPK_354620.1 OG7 LdBPK_201740.1 ↔ LdBPK_354620.1	Both
LAEL147_000348700 alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_005710	Both
LAEL147_000401300 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_005414 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_005710	Both
LAEL147_000067600 hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_005710 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_005710	Both
LAEL147_000807600 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_005710	OG6
LAEL147_000479700 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_005710	OG6
LAEL147_000597200 ⚠ N-acyl-L-amino acid amidohydrolase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_354620.1 OG6 LdBPK_201740.1 ↔ LdBPK_354620.1 OG7 LdBPK_201720.1 ↔ LdBPK_354620.1 OG7 LdBPK_201740.1 ↔ LdBPK_354620.1	Both
LAEL147_000408000 DNL zinc finger containing protein, putative	—	OG6 LdBPK_250830.1 ↔ LdBPK_354620.1 OG7 LdBPK_250830.1 ↔ LdBPK_354620.1	Both
LAEL147_000277200 polyprenyl synthase, putative	—	OG6 LdBPK_190210.1 ↔ LdBPK_354620.1 OG7 LdBPK_190210.1 ↔ LdBPK_354620.1	Both

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