LAEL147_000476200

ribonucleoside-diphosphate reductase small chain, putative
Leishmania aethiopica L147 OG6: OG6_100537 OG7: OG7_0003661 98 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 98 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000165200 ⚠
ornithine decarboxylase, putative
— Both
LAEL147_000432900 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000354300 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LAEL147_000090900 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LAEL147_000140400 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAEL147_000782300 ⚠
ATP-dependent RNA helicase, putative
— OG7
LAEL147_000831400 ⚠
DEAD box RNA helicase, putative
— OG7
LAEL147_000284300 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LAEL147_000467600 ⚠
Carboxypeptidase Taq (M32) metallopeptidase,
— OG7
LAEL147_000467500 ⚠
hypothetical protein
— OG7
LAEL147_000369600 ⚠
aminoacyclase, putative
— OG7
LAEL147_000016600 ⚠
heat shock protein HslVU, ATPase subunit HslU
— Both
LAEL147_000883100 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
LAEL147_000243900 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000301000 ⚠
conserved protein, unknown function
— Both
LAEL147_000170700 ⚠
N-acyl-L-amino acid amidohydrolase
— Both
LAEL147_000561600 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LAEL147_000597200 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LAEL147_000597400 ⚠
Peptidase family M20/M25/M40, putative
— Both
LAEL147_000597300 ⚠
hypothetical protein
— Both
LAEL147_000311000 ⚠
hypothetical protein
— Both
LAEL147_000848300 ⚠
cysteine synthase
— OG6
LAEL147_000244000 ⚠
cystathionine beta-synthase
— Both
LAEL147_000538900 ⚠
Leucine-rich repeat, putative
— Both
LAEL147_000835100 ⚠
FYVE zinc finger containing protein, putative
— Both
LAEL147_000090800 ⚠
hypothetical protein
— OG7
LAEL147_000356100 ⚠
trypanothione synthetase, putative
— OG7
LAEL147_000425300 ⚠
glutathionylspermidine synthase, putative
— OG7
LAEL147_000222700 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
LAEL147_000696900 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LAEL147_000425500 ⚠
hypothetical protein
— OG7
LAEL147_000425400 ⚠
glutathionylspermidine synthase, putative
— OG7
LAEL147_000016300 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
LAEL147_000697300 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LAEL147_000880100 ⚠
protein transport protein Sec23-like protein
— OG7
LAEL147_000347400 ⚠
fk506-binding protein 1-like protein
— OG7
LAEL147_000290800 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LAEL147_000433000 ⚠
Regulator of chromosome condensation (RCC1) r
— Both
LAEL147_000628800 ⚠
Leucine rich repeat, putative
— OG7
LAEL147_000721600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000625000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LAEL147_000809800 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LAEL147_000150200 ⚠
chromatin binding protein, putative
— OG7
LAEL147_000837100 ⚠
cyclin-e binding protein 1-like protein
— OG7
LAEL147_000131900 ⚠
DEAD/DEAH box helicase, putative
— OG7
LAEL147_000862600 ⚠
Leucine rich repeat, putative
— OG7
LAEL147_000853800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000101700 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LAEL147_000005500 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000339300 ⚠
Rab-GTPase-TBC domain containing protein, put
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.