LAEL147_000883100

2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Leishmania aethiopica L147 OG6: OG6_103540 OG7: OG7_0008253 165 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 165 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000617500 ⚠
aldehyde reductase, putative
— OG7
LAEL147_000757500 ⚠
aspartate aminotransferase, putative
— Both
LAEL147_000261200 ⚠
Dephospho-CoA kinase, putative
— Both
LAEL147_000493500
WD domain, G-beta repeat, putative
— Both
LAEL147_000643300 ⚠
cytidyltransferase-like domain containing pro
— Both
LAEL147_000493900
electron-transfer-flavoprotein, alpha polypep
— Both
LAEL147_000371900 ⚠
alanine racemase, putative
— Both
LAEL147_000337400
SEP domain containing protein, putative
— Both
LAEL147_000372000 ⚠
Alanine racemase, N-terminal domain containin
— Both
LAEL147_000630800
Alpha/beta hydrolase family, putative
— Both
LAEL147_000742100
phosphomannomutase-like protein
— Both
LAEL147_000244000 ⚠
cystathionine beta-synthase
— Both
LAEL147_000848300 ⚠
cysteine synthase
— OG6
LAEL147_000587600
ubiquitin hydrolase, putative
— Both
LAEL147_000504200
tRNA threonylcarbamoyl adenosine modification
— Both
LAEL147_000696700 ⚠
transcription elongation factor-like protein
— Both
LAEL147_000021100
cyclophilin 12, putative
— OG6
LAEL147_000148100 ⚠
acidocalcisomal pyrophosphatase
— Both
LAEL147_000045300 ⚠
inorganic pyrophosphatase, putative
— Both
LAEL147_000345600 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LAEL147_000381500 ⚠
malic enzyme, putative
— Both
LAEL147_000474200 ⚠
trypanothione synthetase, putative
— Both
LAEL147_000613000 ⚠
uridine kinase-like protein
— Both
LAEL147_000560200
pyridoxal kinase, putative
— Both
LAEL147_000193600
threonine synthase, putative
— Both
LAEL147_000476200 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LAEL147_000502900
ribose 5-phosphate isomerase, putative
— Both
LAEL147_000382300
triosephosphate isomerase
— Both
LAEL147_000433800
aspartate--ammonia ligase, putative
— Both
LAEL147_000545100
inosine-adenosine-guanosine-nucleoside hydrol
— Both
LAEL147_000052100
spermidine synthase
— Both
LAEL147_000512400
cytosolic malate dehydrogenase
— Both
LAEL147_000714100 ⚠
uracil phosphoribosyltransferase, putative
— Both
LAEL147_000381400 ⚠
malic enzyme, putative
— Both
LAEL147_000703800 ⚠
malate dehydrogenase, putative
— OG7
LAEL147_000019200 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000704000 ⚠
malate dehydrogenase, putative
— OG7
LAEL147_000282400 ⚠
glycosomal malate dehydrogenase
— OG7
LAEL147_000188700 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000589200 ⚠
mitotic centromere-associated kinesin (MCAK),
— OG7
LAEL147_000174400 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000108900
hypothetical protein, conserved
— OG7
LAEL147_000007800 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
LAEL147_000813100 ⚠
ubiquitin-like protein, putative
— OG7
LAEL147_000536900 ⚠
serine/threonine protein kinase, putative
— OG7
LAEL147_000816800 ⚠
SNF1-related protein kinases, putative
— OG7
LAEL147_000508800 ⚠
eukaryotic translation initiation factor 4e,
— OG7
LAEL147_000332800 ⚠
RNA polymerase II, putative
— OG7
LAEL147_000660700 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LAEL147_000337600 ⚠
methylenetetrahydrofolate dehydrogenase-like
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.