LAEL147_000589200

mitotic centromere-associated kinesin (MCAK), putative
Leishmania aethiopica L147 OG6: OG6_139683 OG7: OG7_0003411 158 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 158 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000841100 ⚠
predicted zinc finger protein
— OG7
LAEL147_000327200 ⚠
Ring finger domain containing protein, putati
— OG7
LAEL147_000370700 ⚠
RING-H2 zinc finger containing protein, putat
— OG7
LAEL147_000403200 ⚠
Ring finger domain containing protein, putati
— OG7
LAEL147_000242300 ⚠
Ring finger domain containing protein, putati
— OG7
LAEL147_000429800 ⚠
pseudouridylate synthase-like protein
— OG7
LAEL147_000536100 ⚠
protein farnesyltransferase alpha subunit, pu
— OG7
LAEL147_000337700 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG7
LAEL147_000749500 ⚠
pyruvate kinase
— OG7
LAEL147_000496400 ⚠
hypothetical protein
— OG7
LAEL147_000603400 ⚠
diphthine synthase-like protein
— OG7
LAEL147_000133800 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— OG7
LAEL147_000084600 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000450200 ⚠
Zn-finger in Ran binding protein and others/S
— OG7
LAEL147_000528800 ⚠
carnitine/choline acetyltransferase, putative
— OG7
LAEL147_000631400 ⚠
ubiquitin-conjugating enzyme protein, putativ
— OG7
LAEL147_000428800 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
LAEL147_000318600 ⚠
phosphoglucomutase, putative
— OG7
LAEL147_000313300 ⚠
serine/threonine-protein kinase-like protein
— OG7
LAEL147_000077900 ⚠
U-box domain containing protein, putative
— OG7
LAEL147_000290300 ⚠
eukaryotic translation initiation factor-like
— OG7
LAEL147_000097700 ⚠
serine/threonine kinase, putative
— OG7
LAEL147_000556700 ⚠
conserved hypothetical protein, putative
— OG7
LAEL147_000522700 ⚠
U-box domain protein, putative
— OG7
LAEL147_000010200 ⚠
biotin/lipoate protein ligase-like protein
— OG7
LAEL147_000675200 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
LAEL147_000660800 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LAEL147_000797000 ⚠
CS domain containing protein, putative
— OG7
LAEL147_000742100 ⚠
phosphomannomutase-like protein
— OG7
LAEL147_000254500 ⚠
5'-3' exonuclease, putative
— OG7
LAEL147_000074300 ⚠
5'-3' exonuclease, putative
— OG7
LAEL147_000337600 ⚠
methylenetetrahydrofolate dehydrogenase-like
— OG7
LAEL147_000493900 ⚠
electron-transfer-flavoprotein, alpha polypep
— OG7
LAEL147_000774900 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000448400 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000686600 ⚠
Ribosome assembly protein rrb1, putative
— OG7
LAEL147_000857100 ⚠
ubiquitin protein ligase, putative
— OG7
LAEL147_000699100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000284800 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LAEL147_000632800 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAEL147_000438500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000646700 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000479900 ⚠
aldo-keto reductase-like protein
— OG7
LAEL147_000065500 ⚠
Surp module, putative
— OG7
LAEL147_000231500 ⚠
transaldolase, putative
— OG7
LAEL147_000372000 ⚠
Alanine racemase, N-terminal domain containin
— OG7
LAEL147_000371900 ⚠
alanine racemase, putative
— OG7
LAEL147_000617500 ⚠
aldehyde reductase, putative
— OG7
LAEL147_000337400 ⚠
SEP domain containing protein, putative
— OG7
LAEL147_000356500 ⚠
5'-AMP-activated protein kinase beta subunit,
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.