LAEL147_000450200

Zn-finger in Ran binding protein and others/SPRY domain/HECT-domain (ubiquitin-transferase), putative
Leishmania aethiopica L147 OG6: OG6_146743 OG7: OG7_0043053 201 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 201 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000738100
Zinc finger domain containing protein, putati
— Both
LAEL147_000087400 ⚠
alpha-adaptin-like protein
— OG7
LAEL147_000744400 ⚠
adaptor gamma-1 chain, putative
— OG7
LAEL147_000479900 ⚠
aldo-keto reductase-like protein
— OG7
LAEL147_000617500 ⚠
aldehyde reductase, putative
— OG7
LAEL147_000108900
hypothetical protein, conserved
— OG7
LAEL147_000174400 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000589200 ⚠
mitotic centromere-associated kinesin (MCAK),
— OG7
LAEL147_000188700 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000019200 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000053900
hypothetical protein, conserved
— Both
LAEL147_000045300 ⚠
inorganic pyrophosphatase, putative
— Both
LAEL147_000148100 ⚠
acidocalcisomal pyrophosphatase
— Both
LAEL147_000711900 ⚠
elongation factor 1-beta
— Both
LAEL147_000694800 ⚠
dynein intermediate chain, putative
— Both
LAEL147_000683000
hypothetical protein, conserved
— Both
LAEL147_000652200
CS domain/TPR repeat/Tetratricopeptide repeat
— Both
LAEL147_000886800
elks delta-like protein
— Both
LAEL147_000690700
hypothetical protein, conserved
— Both
LAEL147_000774100
hypothetical protein, conserved
— Both
LAEL147_000887000
eukaryotic translation initiation factor 3 su
— Both
LAEL147_000711600 ⚠
elongation factor 1-beta
— Both
LAEL147_000578900
eukaryotic translation initiation factor 3 su
— Both
LAEL147_000713700 ⚠
myosin IB heavy chain, putative
— Both
LAEL147_000579100
kinesin, putative
— OG6
LAEL147_000596000
hypothetical protein, conserved
— Both
LAEL147_000021100
cyclophilin 12, putative
— OG6
LAEL147_000168700
Tetratricopeptide repeats, putative
— Both
LAEL147_000325700
hypothetical protein, conserved
— Both
LAEL147_000384400
AKAP7 2'5' RNA ligase-like domain containing
— Both
LAEL147_000630800
Alpha/beta hydrolase family, putative
— Both
LAEL147_000214900
hypothetical protein, conserved
— Both
LAEL147_000206800
WD40 repeats, putative
— Both
LAEL147_000742100
phosphomannomutase-like protein
— Both
LAEL147_000587600
ubiquitin hydrolase, putative
— Both
LAEL147_000675200
nicotinate phosphoribosyltransferase, putativ
— Both
LAEL147_000504200
tRNA threonylcarbamoyl adenosine modification
— Both
LAEL147_000696700 ⚠
transcription elongation factor-like protein
— Both
LAEL147_000416900
hypothetical protein, conserved
— Both
LAEL147_000711800 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAEL147_000822800 ⚠
translation elongation factor 1-beta, putativ
— Both
LAEL147_000712200
hypothetical protein, conserved
— Both
LAEL147_000862000
WD domain, G-beta repeat, putative
— Both
LAEL147_000510000
coatomer gamma subunit, putative
— Both
LAEL147_000726600 ⚠
Sec7 domain containing protein, putative
— Both
LAEL147_000526800
hypothetical protein, conserved
— Both
LAEL147_000633200
hypothetical protein, conserved
— Both
LAEL147_000480100
hypothetical protein, conserved
— Both
LAEL147_000311900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000747800
coatomer alpha subunit, putative
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.