LAEL147_000652200

CS domain/TPR repeat/Tetratricopeptide repeat, putative
Leishmania aethiopica L147 OG6: OG6_105298 OG7: OG7_0010785 59 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 59 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000270700 ⚠
pre-RNA processing PIH1/Nop17, putative
— Both
LAEL147_000748300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LAEL147_000636700 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LAEL147_000841200 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LAEL147_000304900 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LAEL147_000029000 ⚠
phosphatidylinositol kinase related protein,
— OG7
LAEL147_000878100 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LAEL147_000743800 ⚠
target of rapamycin kinase (TOR) kinase 3
— Both
LAEL147_000795500 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
LAEL147_000665700
trans-splicing factor, putative
— Both
LAEL147_000579100
kinesin, putative
— OG6
LAEL147_000402900
hypothetical protein, conserved
— Both
LAEL147_000614600 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— Both
LAEL147_000596000
hypothetical protein, conserved
— Both
LAEL147_000051300 ⚠
Nucleotidyltransferase domain containing prot
— Both
LAEL147_000214900
hypothetical protein, conserved
— Both
LAEL147_000526800
hypothetical protein, conserved
— Both
LAEL147_000416900
hypothetical protein, conserved
— Both
LAEL147_000432800
hypothetical protein, conserved
— Both
LAEL147_000450200
Zn-finger in Ran binding protein and others/S
— Both
LAEL147_000561800 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000727700 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAEL147_000511300 ⚠
receptor for activated C kinase 1
— OG7
LAEL147_000511200 ⚠
receptor for activated C kinase 1
— OG7
LAEL147_000813500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000534700 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LAEL147_000088000 ⚠
Sec7 domain containing protein, putative
— OG7
LAEL147_000309100 ⚠
zinc-binding phosphatase, putative
— OG7
LAEL147_000430500 ⚠
DNA polymerase sigma-like protein
— OG7
LAEL147_000853100 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LAEL147_000095200 ⚠
topoisomerase-related function protein-like p
— OG7
LAEL147_000866500
glycosyl hydrolase, putative
— Both
LAEL147_000075500 ⚠
hypothetical protein, conserved
— Both
LAEL147_000510000
coatomer gamma subunit, putative
— Both
LAEL147_000075900 ⚠
hypothetical protein, conserved
— Both
LAEL147_000165800 ⚠
Myotubularin-like phosphatase domain containi
— Both
LAEL147_000051600
hypothetical protein, conserved
— Both
LAEL147_000578900
eukaryotic translation initiation factor 3 su
— Both
LAEL147_000601000
hypothetical protein, conserved
— Both
LAEL147_000055300
hypothetical protein, conserved
— Both
LAEL147_000175100
Lipase (class 3), putative
— Both
LAEL147_000671900
hypothetical protein, conserved
— Both
LAEL147_000614700 ⚠
acetoin dehydrogenase e3 component-like prote
— Both
LAEL147_000105300
hypothetical protein, conserved
— Both
LAEL147_000273200
NADH-ubiquinone oxidoreductase complex I subu
— Both
LAEL147_000318100
RNA helicase, putative
— Both
LAEL147_000325400
U4/U6 small nuclear ribonuclear protein, puta
— OG6
LAEL147_000194700
mRNA capping enzyme, beta chain, putative
— Both
LAEL147_000193100
hypothetical protein, conserved
— Both
LAEL147_000723500
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.