LAEL147_000270700

pre-RNA processing PIH1/Nop17, putative
Leishmania aethiopica L147 OG6: OG6_105060 OG7: OG7_0006226 68 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 68 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000652200 ⚠
CS domain/TPR repeat/Tetratricopeptide repeat
— Both
LAEL147_000304900 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LAEL147_000853100 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LAEL147_000813500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000106700 ⚠
eukaryotic translation initiation factor 2 be
— OG7
LAEL147_000051300 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LAEL147_000430500 ⚠
DNA polymerase sigma-like protein
— OG7
LAEL147_000878100 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LAEL147_000029000 ⚠
phosphatidylinositol kinase related protein,
— OG7
LAEL147_000511200 ⚠
receptor for activated C kinase 1
— OG7
LAEL147_000841200 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LAEL147_000636700 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LAEL147_000748300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LAEL147_000193100 ⚠
hypothetical protein, conserved
— Both
LAEL147_000194700 ⚠
mRNA capping enzyme, beta chain, putative
— Both
LAEL147_000325400
U4/U6 small nuclear ribonuclear protein, puta
— OG6
LAEL147_000866500 ⚠
glycosyl hydrolase, putative
— Both
LAEL147_000273200 ⚠
NADH-ubiquinone oxidoreductase complex I subu
— Both
LAEL147_000237600 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LAEL147_000376200 ⚠
dynein intermediate-chain-like protein
— OG7
LAEL147_000088000 ⚠
Sec7 domain containing protein, putative
— OG7
LAEL147_000515400 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000203600 ⚠
WD40 repeats, putative
— OG7
LAEL147_000727700 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAEL147_000662900 ⚠
myosin XXI
— OG7
LAEL147_000706300 ⚠
RNA polymerase ii largest subunit
— OG7
LAEL147_000014400 ⚠
RNA polymerase ii largest subunit
— OG7
LAEL147_000361900 ⚠
mitochondrial RNA binding protein, putative
— Both
LAEL147_000614300 ⚠
RNA polymerase ii largest subunit
— OG7
LAEL147_000166200 ⚠
Glutathione S-transferase, N-terminal domain
— OG7
LAEL147_000682500 ⚠
elongation factor 1-gamma, putative
— OG7
LAEL147_000534700 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LAEL147_000095200 ⚠
topoisomerase-related function protein-like p
— OG7
LAEL147_000561800 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000511300 ⚠
receptor for activated C kinase 1
— OG7
LAEL147_000345400 ⚠
MORN repeat, putative
— Both
LAEL147_000579100
kinesin, putative
— OG6
LAEL147_000596000 ⚠
hypothetical protein, conserved
— Both
LAEL147_000416900 ⚠
hypothetical protein, conserved
— Both
LAEL147_000712200 ⚠
hypothetical protein, conserved
— Both
LAEL147_000510000 ⚠
coatomer gamma subunit, putative
— Both
LAEL147_000447900 ⚠
hypothetical protein, conserved
— Both
LAEL147_000726600 ⚠
Sec7 domain containing protein, putative
— Both
LAEL147_000285800 ⚠
hypothetical protein, conserved
— Both
LAEL147_000713700 ⚠
myosin IB heavy chain, putative
— Both
LAEL147_000384400 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— Both
LAEL147_000755400 ⚠
hypothetical protein, conserved
— Both
LAEL147_000747800 ⚠
coatomer alpha subunit, putative
— Both
LAEL147_000526800 ⚠
hypothetical protein, conserved
— Both
LAEL147_000402900 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.