LAEL147_000706300

RNA polymerase ii largest subunit
Leishmania aethiopica L147 OG6: OG6_100210 OG7: OG7_0001854 168 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 168 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000281800 ⚠
DNA-directed RNA polymerases I and III subuni
— +2 more Both
LAEL147_000111300 ⚠
phosphoribosylpyrophosphate synthetase
— Both
LAEL147_000618400 ⚠
acetyl-CoA carboxylase, putative
— Both
LAEL147_000106200 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
LAEL147_000515800 ⚠
DNA-directed RNA polymerase I-like protein
— +1 more Both
LAEL147_000292700 ⚠
DNA-directed RNA polymerase polypeptide, puta
— +4 more Both
LAEL147_000587800 ⚠
DNA-directed RNA polymerase polypeptide, puta
— +4 more Both
LAEL147_000406100 ⚠
RNA polymerase I second largest subunit, puta
— +1 more OG7
LAEL147_000868200 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LAEL147_000686900 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LAEL147_000535600 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000841200 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LAEL147_000264000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAEL147_000745600 ⚠
GRIP domain containing protein, putative
— OG7
LAEL147_000224500 ⚠
AAA domain containing protein, putative
— OG7
LAEL147_000676900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000263700 ⚠
Flagellar-associated PapD-like, putative
— OG7
LAEL147_000436500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000402600 ⚠
RNA-binding protein, putative
— OG7
LAEL147_000794800 ⚠
predicted zinc finger protein
— OG7
LAEL147_000373200 ⚠
neutral sphingomyelinase activation associate
— OG7
LAEL147_000349700 ⚠
CCR4 associated factor, putative
— OG7
LAEL147_000392200 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAEL147_000801400 ⚠
DNA replication licensing factor MCM9, putati
— OG7
LAEL147_000382900 ⚠
DNA replication licensing factor MCM5, putati
— OG7
LAEL147_000326700 ⚠
adenylate kinase, putative
— OG7
LAEL147_000384900 ⚠
formin, putative
— OG7
LAEL147_000628700 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000884500 ⚠
beta-adaptin, putative
— OG7
LAEL147_000722100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000821900 ⚠
adenylate kinase, putative
— OG7
LAEL147_000056000 ⚠
adenylate kinase, putative
— OG7
LAEL147_000304900 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LAEL147_000029000 ⚠
phosphatidylinositol kinase related protein,
— OG7
LAEL147_000284400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000866800 ⚠
adaptin, putative
— OG7
LAEL147_000398800 ⚠
cullin-like protein-like protein
— OG7
LAEL147_000635700 ⚠
RNA guanylyltransferase, putative
— OG7
LAEL147_000549100 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000463200 ⚠
parallel beta-helix repeat, putative
— OG7
LAEL147_000775200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000724600 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
LAEL147_000357500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000205100 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LAEL147_000614700 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LAEL147_000656300 ⚠
NADH dehydrogenase subunit NI8M, putative
— OG7
LAEL147_000413400 ⚠
PRP38 family, putative
— OG7
LAEL147_000157100 ⚠
adaptin-related protein-like protein
— OG7
LAEL147_000351700 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LAEL147_000141700 ⚠
histone H3, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.